2-Thiophenesulfonyl chloride
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Basic information
- CAS
16629-19-9- Standard SMILES
O=S(=O)(Cl)c1cccs1- InChIKey
VNNLHYZDXIBHKZ-UHFFFAOYSA-N- Molecular formula
- C4H3ClO2S2
- Average molar mass
- 182.7 g/mol
- Monoisotopic mass
- 181.92629902
Names & identifiers
- Preferred name
- 2-Thiophenesulfonyl chloride
- IUPAC
- thiophene-2-sulfonyl chloride
- English name
- 2-Thiophenesulfonyl chloride
- Molecular formula
- C4H3ClO2S2
- Molecular weight
- 182.65
Names & synonyms
2-Thiophenesulfonyl chloride16629-19-9Thiophene-2-sulphonyl chlorideEINECS 240-677-1DTXSID9066093RefChem:483802DTXCID9035339240-677-1Thiophene-2-sulfonyl chloride2-Thienylsulfonyl chlorideMFCD00005426thiophene-2-sulfonylchloride
Show more names
AKOS B0193972-ThiophenesuL2-Thienylsulfonyl2-ThiophenesulfonylART-CHEM-BB B019397TIMTEC-BB SBB003729OTAVA-BB BB7020430954LABOTEST-BB LT00112344
2-thiophene sulfonyl chloridechloro-2-thienylsulfone2-thiophenesulfonylchloride2-thiophenesulphonyl chloridethiophenesulfonyl chloride2-thienylsulphonylchloride2-chlorosulfonyl thiophene2-chlorosulfonyl-thiophene
Database identifiers
- CAS
16629-19-9- PubChem CID
- 85518
- DTXSID
DTXSID9066093- EC Number
- 240-677-1
- Nikkaji
- J151.061D
Properties
Computed structural propertiesFilling in
- XLogP
- 1.2
- Topological polar surface area
- 70.8 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 1
- Heavy atoms
- 9
- Formal charge
- 0
- Complexity
- 181
Experimental & physicochemical properties
SpringerMaterials PropertiesSchoenflies notation
Physicochemical properties
- Melting point
- 30 · 30-32 °C(lit.)
- Boiling point
- 130 · 130-132 °C14 mm Hg(lit.)
- Density
- 1.534 · 1.534 (estimate)
- refractive index
- 1.5722 · 1.5722-1.5742
- Flash point
- 110 °C · >110°C
- storage temp.
- 2 · Keep in dark place,Inert atmosphere,2-8°C
- solubility
- soluble in Chloroform, Ethyl Acetate
- form
- solid
- color
- White to Almost white
- Water Solubility
- Reacts with water.
- Sensitive
- Moisture Sensitive
- BRN
- 123536 · 123536
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
P260, P264, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P363, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 48 reports by companies from 4 notifications to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesSkin Corr. 1B (100%)
Safety data
- F
- 10-21
- PPE
- Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
- wgk
- 3
- tsca
- TSCA listed
- ridadr
- UN 3261 8/PG 2
- hs_code
- 29349990
- risk_code
- 34
- Signal word
- Danger
- Symbol(GHS)
- GHS05
- hazard_code
- C
- hazard_note
- Corrosive
- safety_code
- 26-36/37/39-45-28A-25-27
- hazard_class
- 8
- Storage Class
- 8A - Combustible corrosive hazardous materials
- packing_group
- II
- Hazard statements
- H314
Chemistry & industry
Uses & manufacturing
General Manufacturing Information2-Thiophenesulfonyl chloride: INACTIVE
Applications
Uses2-Thiophenesulfonyl chloride has been used in the preparation of 2-((trans-2-phenyl cyclopropyl)sulfonyl)thiophene
Uses2-Thiophenesulfonyl chloride is a compound used in the preparation of various pharmaceuticals. Thiophene-2-sulfonyl Chloride was used as an intermediate in the synthesis of β-Cell apoptosis supressor .
General DescriptionKinetics of reactions of 2-thiophenesulfonyl chloride with substituted anilines in methanol has been reported. Kinetics of solvolysis of 2-thiophenesulfonyl chloride in binary solvent mixtures has been studied.
Upstream & downstream products
Upstream raw materials
Related reactions
389 records
Compound notes
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