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Basic information
- CAS
16714-78-6- Standard SMILES
O=C(CCl)CCCl- InChIKey
UDNZDMGFDFBONM-UHFFFAOYSA-N- Molecular formula
- C4H6Cl2O
- Average molar mass
- 140.997 g/mol
- Monoisotopic mass
- 139.97957017
Names & identifiers
- Preferred name
- 1,4-Dichlorobutan-2-one
- IUPAC
- 1,4-Dichlorobutan-2-one
- English name
- 1,4-dichlorobutan-2-one
- Molecular formula
- C4H6Cl2O
- Molecular weight
- 141
Names & synonyms
Einecs 240-768-61,4-dichlorobutan-2-one2-Butanone,1,4-dichloro1,4-Dichloro-2-butanone(2-Chloroethyl)(chloromethyl) ketone
Database identifiers
- CAS
16714-78-6- PubChem CID
- 85563
- DTXSID
DTXSID40168234- EC Number
- 240-768-6
- Nikkaji
- J236.835H
Properties
Physicochemical properties
- Boiling point
- 65 °C · 65 °C(Press: 3 Torr)
- Density
- 1.3295 g/cm3 · 1.3295 g/cm3
- solubility
- freely sol organics; may react with amides, amines, alcohols, sulfoxides, water
- form
- neat liquid
- Symbol(GHS)
- 7 · GHS07,GHS05
- Signal word
- Danger
- Hazard statements
- 315 · H315-H335-H318
- Precautionary statements
- 280 · P280-P305+P351+P338-P310-P264-P280-P302+P352-P321-P332+P313-P362
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Signal word
- Danger
- Symbol(GHS)
- GHS07,GHS05
- Hazard statements
- H315-H335-H318
- Precautionary statements
- P280-P305+P351+P338-P310-P264-P280-P302+P352-P321-P332+P313-P362
Chemistry & industry
Applications
Uses1,4-dichloro-Butanone is a reagent used as a reactive electrophile precursor for 1,4-disubstituted 2-butanones and 2-butenones.
Preparation methods
Preparation1,4-Dichloro-2-butanone can be prepared by the Friedel-Crafts acylation of ethylene with Chloroacetyl Chloride catalyzed by Aluminum Chloride or the treatment of 2-chloropropionyl chloride with Diazomethane followed by concentrated HCl. The Friedel-Crafts process can be used with other alkenes and acid chlorides to yield α,β′-dichloroalkyl ketones.
Upstream & downstream products
Downstream products
Suppliers9 total
上海健超生物科技有限公司15021035486 18081542813 · [email protected]
江苏艾康生物医药研发有限公司025-66028182 17714375163 · [email protected]
济南岑奔医药科技有限公司14793566 · [email protected]
重庆艾思摩尔科技有限公司023-86822659 18611316925 · [email protected]
济南尚博医药股份有限公司0531-61320525 15866703830 · [email protected]
济南尚博生物科技有限公司+8615866703830 · [email protected]
BOC Sciences+1-631-485-4226 · [email protected]
Related reactions
2 records
Compound notes
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