Basic information
- CAS
131-49-7- Standard SMILES
CC(=O)Nc1c(I)c(NC(C)=O)c(I)c(C(=O)O)c1I.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO- InChIKey
MIKKOBKEXMRYFQ-WZTVWXICSA-N- Molecular formula
- C18H26I3N3O9
- Average molar mass
- 809.1 g/mol
- Monoisotopic mass
- 808.8803
Overview
Diatrizoate Meglumine is the meglumine salt form of diatrizoate, an organic, iodinated, radiopaque X-ray contrast medium used in diagnostic radiography. The iodine moiety of diatrizoate meglumine is not penetrable by X-rays, therefore blocks the X-ray film exposure by radiation. This makes it possible to distinguish on X-ray film, body parts that contain diatrizoate meglumine from body parts that do not contain this agent and allows for visualization of different body structures.
Names & identifiers
- Preferred name
- Meglumine Diatrizoate
- IUPAC
- 3,5-diacetamido-2,4,6-triiodobenzoic acid;(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol
- English name
- MEGLUMINE DIATRIZOATE
- Molecular formula
- C18H26I3N3O9
- Molecular weight
- 809.13
Names & synonyms
Meglumine diatrizoateDIATRIZOATE MEGLUMINE131-49-7Meglumine amidotrizoateCardiografinCystografinAngiovist 282Urovist CystoRenoAmidotrizoate meglumineHypaque-cystoReno-dip
Show more names
d-renom60renurixRenocalunipaque18O,96%）Renovisthypaque60
Reno-30Urovist Cysto PediatricCystografin DiluteUrovist Meglumine Diu/ctDiatrizoate methylglucamineMethylglucamine diatrizoateReno-60Diatrizoic acid meglumine salt
Database identifiers
- CAS
131-49-7- PubChem CID
- 8566
- DTXSID
DTXSID20897171- ChEMBL
CHEMBL1200839- UNII
- 3X9MR4N98U
- EC Number
- 205-024-7
Properties
Computed structural properties
- Topological polar surface area
- 209 Ų
- Hydrogen bond donors
- 9
- Hydrogen bond acceptors
- 10
- Rotatable bonds
- 9
- Heavy atoms
- 33
- Formal charge
- 0
- Complexity
- 525
Experimental & physicochemical properties
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
Animal DrugsFDA approved animal drugs -> Active ingredient
Physicochemical properties
- Melting point
- 189 · 189-193° (dec)
- Density
- 1.9465 · 1.9465 (estimate)
- storage temp.
- Refrigerator
- solubility
- DMSO (Slightly), Water (Slightly)
- form
- Solid
- color
- Rhombic needles
- Odor
- sltly sweet taste
- biological source
- synthetic (organic)
- optical activity
- 25 · [α]25/D -6.4 to -5.7 °, c =1% (w/v) in water
- InChIKey
- MIKKOBKEXMRYFQ-KUAVVOKVNA-N
- SMILES
- N(C1C(=C(NC(=O)C)C(I)=C(C(=O)O)C=1I)I)C(=O)C.[C@@H](O)([C@@H](O)CNC)[C@H](O)[C@H](O)CO |&1:20,22,27,29,r|
Safety & regulation
Hazard information
Other Safety InformationIMAP assessments - D-Glucitol, 1-deoxy-1-(methylamino)-, 3,5-bis(acetylamino)-2,4,6-triiodobenzoate (salt): Environment tier I assessment
Safety data
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 3
- rtecs
- LZ4315000
- Toxicity
- TDLo scu-man: 214 mg/kg 34ZIAG -,392,69
- Storage Class
- 11 - Combustible Solids
Chemistry & industry
Pharmacology
FDA Pharmacological Classification
DIATRIZOATE MEGLUMINE
X-Ray Contrast Activity [MoA]; Radiographic Contrast Agent [EPC]
MeSH Pharmacological ClassificationSubstances used to allow enhanced visualization of tissues.
Applications
UsesMeglumine diatrizoate can be used to treat long-term Taenia saginata infection. It has also been used to tag fecal matter and bodily fluids in a study investigating preoperative examination techniques in patients with acute colon obstruction caused by colorectal cancer.
UsesMedicine (radiopaque medium).
Suppliers85 total
湖南韵邦生物科技股份有限公司85561037 15386497078 · [email protected]
Hebei Chuanghai Biotechnology Co., Ltd+86-17732866630 · [email protected]
湖北威德利化学试剂有限公司181-6332-1995 18062128043 · [email protected]
武汉灵灵九生物科技有限公司15623309010
湖北研科时代科技有限公司15780669880 · [email protected]
江苏艾康生物医药研发有限公司025-025-66113011 15955137747 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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