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Basic information
- CAS
134-29-2- Standard SMILES
COc1ccccc1N.Cl- InChIKey
XCZCWGVXRBJCCD-UHFFFAOYSA-N- Molecular formula
- C7H9NO.ClH
- Average molar mass
- 159.61 g/mol
- Monoisotopic mass
- 159.04509162
Overview
o-Anisidine Hydrochloride can cause cancer according to an independent committee of scientific and health experts.
Names & identifiers
- Preferred name
- 2-Anisidine hydrochloride
- IUPAC
- 2-methoxyaniline;hydrochloride
Names & synonyms
Show more names
Database identifiers
- CAS
134-29-2- PubChem CID
- 8638
- DTXSID
DTXSID8020092- ChEMBL
CHEMBL3183318- UNII
- 74SDU6V9SC
- EC Number
- 603-807-1
Properties
Computed structural propertiesFilling in
- Topological polar surface area
- 35.3 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 1
- Heavy atoms
- 10
- Formal charge
- 0
- Complexity
- 85
Experimental & physicochemical properties
Safety & regulation
GHS classification
GHS Classification
Danger
H301+H311+H331 (50%): Toxic if swallowed, in contact with skin or if inhaled [Danger Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]
P203, P260, P261, P262, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P308+P316, P316, P318, P319, P321, P330, P337+P317, P361+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Danger
H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]
Hazard information
Regulatory Information
Hazard Traits - Carcinogenicity
The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)
Reactivity Profile
O-ANISIDINE HYDROCHLORIDE reacts as an acid to neutralize bases. These neutralizations generate some heat. Usually does not react as either an oxidizing agent or reducing agent but such behavior is not impossible. May catalyze organic reactions.
Hazard Classes and Categories
Acute Tox. 3 (100%)
Germ cell mutagenicity - Category 2
Carcinogens
Safety & protection
First Aid
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.
Nonfire Spill Response
SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Toxicology
Carcinogen Classification
ortho-Anisidine hydrochloride
Group 2A: Probably carcinogenic to humans
Volume 127: (2021) Some Aromatic Amines and Related Compounds
2021 online
2020
o-Anisidine hydrochloride
RAIS Toxicity Values
3.1e-05
CALEPA
0.11
CALEPA
Chemistry & industry
Suppliers57 total
Related reactions
Compound notes
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