2-Anisidine hydrochloride

HCID 8638

Completing data — usually done within a minute

Basic information

CAS
134-29-2
Standard SMILES
COc1ccccc1N.Cl
InChIKey
XCZCWGVXRBJCCD-UHFFFAOYSA-N
Molecular formula
C7H9NO.ClH
Average molar mass
159.61 g/mol
Monoisotopic mass
159.04509162

Overview

o-Anisidine Hydrochloride can cause cancer according to an independent committee of scientific and health experts.

Names & identifiers

Preferred name
2-Anisidine hydrochloride
IUPAC
2-methoxyaniline;hydrochloride

Names & synonyms

2-Anisidine hydrochlorideRefChem:167141134-29-22-Methoxyaniline hydrochlorideO-ANISIDINE HYDROCHLORIDEo-Anisidine.HClFast Red BB Base2-Methoxyaniline HClBenzenamine, 2-methoxy-, hydrochlorideO-Anisidine HClo-Anisidine, hydrochlorideo-Methoxyaniline hydrochloride
Show more names
2-Methoxybenzenamine hydrochlorideMFCD000543342-methoxyaniline;hydrochlorideDTXSID8020092C.I. 37115Anisidine hydrochloride, o-74SDU6V9SCDTXCID3092

Database identifiers

CAS
134-29-2
PubChem CID
8638
DTXSID
DTXSID8020092
ChEMBL
CHEMBL3183318
UNII
74SDU6V9SC
EC Number
603-807-1

Properties

Computed structural propertiesFilling in

Topological polar surface area
35.3 Ų
Hydrogen bond donors
2
Hydrogen bond acceptors
2
Rotatable bonds
1
Heavy atoms
10

Experimental & physicochemical properties

Chemical ClassesCarcinogens
Solubility10 to 50 mg/mL at 70 °F (NTP, 1992)
Melting Point437 to 441 °F (NTP, 1992)
Physical DescriptionO-anisidine hydrochloride appears as gray-black crystalline solid or light gray powder. May be carcinogenic.

Safety & regulation

GHS classification

GHS Classification · 6 items

Danger

H301+H311+H331 (50%): Toxic if swallowed, in contact with skin or if inhaled [Danger Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]

P203, P260, P261, P262, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P308+P316, P316, P318, P319, P321, P330, P337+P317, P361+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]

Hazard information

Regulatory Information · 2 items

Hazard Traits - Carcinogenicity

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

Fire HazardsFlash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)
Health HazardsSYMPTOMS: This compound may cause local irritating effects to the eyes, mucous membranes and skin. It may also cause allergic responses.
Reactive GroupEthers
Reactivity Profile · 1 item

O-ANISIDINE HYDROCHLORIDE reacts as an acid to neutralize bases. These neutralizations generate some heat. Usually does not react as either an oxidizing agent or reducing agent but such behavior is not impossible. May catalyze organic reactions.

Air and Water ReactionsWater soluble.

Safety & protection

Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1 item

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 item

SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Personal Protective Equipment (PPE)MINIMUM PROTECTIVE CLOTHING: If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.

Toxicology

Carcinogen Classification · 6 items

ortho-Anisidine hydrochloride

Group 2A: Probably carcinogenic to humans

Volume 127: (2021) Some Aromatic Amines and Related Compounds

2021 online

2020

o-Anisidine hydrochloride

RAIS Toxicity Values · 4 items

3.1e-05

CALEPA

0.11

CALEPA

Chemistry & industry

Suppliers57 total

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
爱斯特(成都)生物制药股份有限公司+86-28-85122536 85324413 · [email protected]

Related reactions

2 records

Compound notes

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