Basic information
- CAS
136-46-9- Standard SMILES
CCOc1ccc(C(=O)OCCN(CC)CC)cc1.Cl- InChIKey
SFLZPZAKIKUJKP-UHFFFAOYSA-N- Molecular formula
- C15H24ClNO3
- Average molar mass
- 301.81 g/mol
- Monoisotopic mass
- 301.1444713
Names & identifiers
- Preferred name
- Benzoic acid, 4-ethoxy-, 2-(diethylamino)ethyl ester, hydrochloride (1:1)
- IUPAC
- 2-(diethylamino)ethyl 4-ethoxybenzoate;hydrochloride
- English name
- 2-(diethylamino)ethyl 4-ethoxybenzoate hydrochloride
- Molecular formula
- C15H23NO3
- Molecular weight
- 265.34802
Names & synonyms
Parethoxycaine hydrochloride136-46-9Parethoxycaine HClIntracaine hydrochloride414P5USJ7FDTXSID80159621RefChem:1079187DTXCID9082112Benzoic acid, 4-ethoxy-, 2-(diethylamino)ethyl ester, hydrochloride (1:1)205-246-42-(Diethylamino)ethyl 4-ethoxybenzoate hydrochlorideMedecaina
Show more names
Parethoxycainep-Ethoxycaine hydrochlorideβ-Diethylaminoethyl-p-ethoxybenzoateParethoxycaine hydrochloride, 10 mM in DMSO4-Ethoxybenzoic acid,2-[diethylamino] ethyl ester4-ethoxybenzoic acid 2-diethylaminoethyl ester hydrochloride
2-(diethylamino)ethyl 4-ethoxybenzoate;hydrochlorideEthoxycaineParaethoxycaineDiethoxinDiethoxineMaxicainMaxicainaMaxicaine
Database identifiers
- CAS
136-46-9
Properties
Computed structural properties
- Topological polar surface area
- 38.8 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 9
- Heavy atoms
- 20
- Formal charge
- 0
- Complexity
- 246
Physicochemical properties
- Melting point
- 172.5 · 172.5-173.5°
- FDA 21 CFR
- 310.545 · 310.545
- FDA UNII
- 414 P5USJ7F · 414P5USJ7F
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 280 · P280-P305+P351+P338
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P280-P305+P351+P338
Chemistry & industry
Applications
UsesParethoxycaine hydrochloride is an anesthetic with nerve conduction blocking activity. Parethoxycaine hydrochloride exhibits non-selective inhibitory effects on responses to various stimulants in rat vas deferens and guinea pig ileum muscles. Parethoxycaine hydrochloride has an enhanced effect on the action of norepinephrine, and its methyl bromide derivative also exhibits the same properties on the action of norepinephrine and potassium ions. Derivatives of parethoxycaine hydrochloride have significant effects on calcium dose-response curves, displaying different tissue and stimulant selectivities. The mechanism of action of Parethoxycaine hydrochloride involves the regulation of calcium transport processes[1].
Suppliers9 total
广州佳途科技股份有限公司81960175-877 18933936954 · [email protected]
普善实业（陕西）有限公司029-81310890 18165209495 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
成都标样生物科技有限公司028-81700200 13308200041 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
DAYANG CHEM (HANGZHOU) CO.,LTD+86-88938639 +86-17705817739 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354 · [email protected]
上海阿摩尔生物科技有限公司13370042665 18916960931 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
Loading…