(4-Hydroxyphenyl)acetamide

HCID 86986
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Basic information

CAS
17194-82-0
Standard SMILES
NC(=O)Cc1ccc(O)cc1
InChIKey
YBPAYPRLUDCSEY-UHFFFAOYSA-N
Molecular formula
C8H9NO2
Average molar mass
151.16 g/mol
Monoisotopic mass
151.06332853

Overview

2-(4-Hydroxyphenyl)acetamide is a member of acetamides.

Names & identifiers

Preferred name
(4-Hydroxyphenyl)acetamide
IUPAC
2-(4-hydroxyphenyl)acetamide
English name
4-Hydroxyphenylacetamide
Molecular formula
C8H9NO2
Molecular weight
151.16

Names & synonyms

17194-82-04-Hydroxybenzeneacetamide(p-Hydroxyphenyl)acetamidep-(Carbamoylmethyl)phenol2-(p-Hydroxyphenyl)acetamide(4-Hydroxyphenyl)acetamide4-(Hydroxyphenyl)acetamideAcetamide, 2-(p-hydroxyphenyl)-0HY0N4ITN4NSC-187193DTXSID4066171RefChem:523998
Show more names
para-HydroxyphenylacetamidePHAA500G1KG5KGAtenlol Imp AATENOLOL IMP ACompound Fr14145Atenlol Impurity AATENOLOL IMPURITY ALABOTEST-BB LT00848172HydroxyphenylacetaMide
DTXCID6035497241-235-04-Hydroxyphenylacetamide2-(4-Hydroxyphenyl)acetamidep-HydroxyphenylacetamideBenzeneacetamide, 4-hydroxy-Atenolol EP Impurity AMFCD00017145

Database identifiers

CAS
17194-82-0
PubChem CID
86986
DTXSID
DTXSID4066171
ChEMBL
CHEMBL447310
ChEBI
CHEBI:194828
UNII
0HY0N4ITN4
EC Number
241-235-0
Nikkaji
J42.257F

Properties

Computed structural properties

XLogP
0.1
Topological polar surface area
63.3 Ų
Hydrogen bond donors
2
Hydrogen bond acceptors
2
Rotatable bonds
2
Heavy atoms
11

Physicochemical properties

Melting point
176 · 176-178 °C (lit.)
Boiling point
273.17 °C · 273.17°C (rough estimate)
Density
1.2023 · 1.2023 (rough estimate)
refractive index
1.581 · 1.5810 (estimate)
storage temp.
Inert atmosphere,Room Temperature
solubility
DMSO (Slightly), Methanol (Slightly)

Safety & regulation

GHS classification

GHS Classification · 4 items

Warning

H315 (94.2%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 52 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Regulatory Information · 2 items

PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.

Status: Active Update: 19-03-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/22972

Hazard Classes and CategoriesSkin Irrit. 2 (94.2%)

Safety data

PPE
dust mask type N95 (US), Eyeshields, Gloves
wgk
3
tsca
TSCA listed
rtecs
AC3851500
hs_code
29242990
risk_code
36/37/38

Chemistry & industry

Uses & manufacturing

General Manufacturing InformationBenzeneacetamide, 4-hydroxy-: INACTIVE

Applications

Uses4-(Hydroxyphenyl)acetamide is used as an intermediate for the synthesis of Atenolol (A790075) and various other organic compounds and pharmaceuticals. It is a process impurity for Atenolol (A790075)

Uses4-(Hydroxyphenyl)acetamide (Atenolol EP Impurity A) is used as an intermediate for the synthesis of Atenolol (A790075) and various other organic compounds and pharmaceuticals. It is a process impurity for Atenolol (A790075)

Upstream & downstream products

Suppliers100 total

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
衢州润东化工有限公司0570-8789886 18892685668 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
INTATRADE GmbH+49 3493/605464 · [email protected]
河北创海生物科技有限公司+86-86-13131129325 · [email protected]

Additional notes

DefinitionChEBI: 2-(4-Hydroxyphenyl)acetamide is a member of acetamides.

Related reactions

15 records
New reaction record

Compound notes

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