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DL-Glutamic acid hydrochloride

HCID 8737
NotesReactions
Basic informationOverviewNames & identifiersPropertiesSafety & regulationChemistry & industryRelated reactionsCompound notes
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Basic information

CAS
138-15-8
Standard SMILES
Cl.NC(CCC(=O)O)C(=O)O
InChIKey
RPAJSBKBKSSMLJ-UHFFFAOYSA-N
Molecular formula
C5H10ClNO4
Average molar mass
183.59 g/mol
Monoisotopic mass
183.0298355

Overview

See also: Glutamic acid, hydrochloride (1:1) (annotation moved to).

Names & identifiers

Preferred name
DL-Glutamic acid hydrochloride
IUPAC
2-aminopentanedioic acid;hydrochloride
English name
L-(+)-Glutamic acid hydrochloride
Molecular formula
C5H10ClNO4
Molecular weight
183.59

Names & synonyms

DL-Glutamic acid hydrochloride2-aminopentanedioic acid;hydrochlorideL-(+)-Glutamic acid hydrochlorideGastuloricHypochylinAcidulinAcidorideMuriamicAcridorideAcidulenAcridogenPepsidol
Show more names
l-glutamicL-GLUTAMIC ACID HCLGLUTAMIC ACID HCLL-GLUTAMIC ACID HYDROCHLORIDEaclorantalkapepsdolacidogenacidalin
Glutan HydrochloricGlutan H-C-L(S)-2-Aminoglutaric acidDL-GLUTAMIC ACID HCLGLUTAMIC ACID, (L)MLS001056749SCHEMBL176818CHEMBL1404532

Database identifiers

CAS
138-15-8、15767-75-6
PubChem CID
8737
DTXSID
DTXSID70935774
ChEMBL
CHEMBL1404532

Properties

Computed structural properties

Topological polar surface area
101 Ų
Hydrogen bond donors
4
Hydrogen bond acceptors
5
Rotatable bonds
4
Heavy atoms
11
Formal charge
0
Complexity
145

Experimental & physicochemical properties

Solubility>27.5 [ug/mL] (The mean of the results at pH 7.4)

Physicochemical properties

Melting point
214 °C · 214 °C (dec.)(lit.)
alpha
25.5 · 25.5 º (c=10, 2N HCl)
Density
1.525 · 1.525
bulk density
630 kg/m3 · 630kg/m3
refractive index
24 ° · 24 ° (C=6, H2O)
storage temp.
30 °C · Store below +30°C.
solubility
2 O: · H2O: 1 M at 20 °C, clear, colorless
form
Crystals For Fine Crystalline Powder
color
White
Odor
100 % · at 100.00%. odorless
Water Solubility
490 g/L · 490 g/L (20 ºC)
Sensitive
Hygroscopic
Merck
14 · 14,4469
BRN
3565569 · 3565569

Safety & regulation

Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.

Safety data

F
3-10
PPE
dust mask type N95 (US), Eyeshields, Gloves
wgk
3
tsca
TSCA listed
ridadr
UN 1789 8/PG 3
hs_code
29224200
risk_code
41
Signal word
Danger
Symbol(GHS)
GHS05
hazard_code
Xi
safety_code
26-39
Storage Class
8A - Combustible corrosive hazardous materials
Hazard statements
H314
Hazard Classifications
Eye Dam. 1Skin Corr. 1
Precautionary statements
P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363

Chemistry & industry

Applications · 3 items

UsesGlutamic Acid Hydrochloride is a flavoring, salt substitute that is soluble in water and very slightly soluble in alcohol and ether. It is obtained by chemical synthesis.

UsesL-Glutamic acid hydrochloride is used as a digestive aid. It is used in cell culture as a component of MEM non-essential amino acids solution. It has been used as a nitrogen source in the culture of Aspergillus fumigatus NRRL 2436 for fumagillin production.

General DescriptionL-glutamate is the major excitatory neurotransmitter in mammalian central nervous system (CNS). It interacts with membrane bound glutamate receptors.

Upstream & downstream products

Upstream raw materials

N-Methyl-L-phenylalanine hydrochlorideL-Arginine hydrochlorideL-Isoleucine hydrochlorideMethyl L-pyroglutamateL-PyroglutaminolN-Carbobenzyloxy-L-proline methyl esterL-Glutamic acidL-Pyroglutamic acid

Downstream products

L-Glutamic acid dimethyl ester hydrochlorideBoc-Glu(OMe)-OH

Suppliers100 total

Related reactions

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Compound notes

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On this pageBasic informationOverviewNames & identifiersPropertiesSafety & regulationChemistry & industryRelated reactionsCompound notes
Stability
Hygroscopic
InChI
1S/C5H9NO4.ClH/c6-3(5(9)10)1-2-4(7)8;/h3H,1-2,6H2,(H,7,8)(H,9,10);1H/t3-;/m0./s1
InChIKey
RPAJSBKBKSSMLJ-DFWYDOINSA-N
SMILES
Cl.N[C@@H](CCC(O)=O)C(O)=O
LogP
-1.435 · -1.435 (est)
CAS DataBase Reference
138 · 138-15-8(CAS DataBase Reference)
SCOGS (Select Committee on GRAS Substances)
L-Glutamic acid hydrochloride
Substances Added to Food (formerly EAFUS)
GLUTAMIC ACID HYDROCHLORIDE
FDA 21 CFR
182.1047 · 182.1047; 310.545
FDA UNII
0 C2SP444T · M0C2SP444T
ATC code
9 AB01 · A09AB01
EPA Substance Registry System
L-Glutamic acid, hydrochloride (138-15-8)
UNSPSC Code
41116107 · 41116107
NACRES
32 · NA.32
Symbol(GHS)
5 · GHS05
Signal word
Danger
Hazard statements
314 · H314
Precautionary statements
260 · P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363
PPE
95 · dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes
Xi
Risk Statements
41 · 41
Safety Statements
26 · 26-39
RIDADR
1789 · UN 1789 8/PG 3
WGK Germany
3 · 3
F
3 · 3-10
TSCA
TSCA listed
HS Code
29224200 · 29224200
Storage Class
8 A · 8A - Combustible corrosive hazardous materials
Hazard Classifications
1 Skin · Eye Dam. 1Skin Corr. 1
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