Basic information
- CAS
18406-41-2- Standard SMILES
CO[Si](CC[Si](OC)(OC)OC)(OC)OC- InChIKey
JCGDCINCKDQXDX-UHFFFAOYSA-N- Molecular formula
- C8H22O6Si2
- Average molar mass
- 270.43 g/mol
- Monoisotopic mass
- 270.09549148
Names & identifiers
- Preferred name
- Hexamethoxydisilylethane
- IUPAC
- trimethoxy(2-trimethoxysilylethyl)silane
- English name
- 1,2-BIS(TRIMETHOXYSILYL)ETHANE
- Molecular formula
- C8H22O6Si2
- Molecular weight
- 270.43
Names & synonyms
Show more names
Database identifiers
- CAS
18406-41-2- PubChem CID
- 87627
- DTXSID
DTXSID6066369- UNII
- LJZ836PHD3
- EC Number
- 242-285-6
- Nikkaji
- J21.120F
Properties
Computed structural properties
- Topological polar surface area
- 55.4 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 9
- Heavy atoms
- 16
- Formal charge
- 0
- Complexity
- 147
Experimental & physicochemical properties
Chemical Classes
Metals -> Metalloid Compounds (Silicon)
Industrial compound
Physicochemical properties
- Melting point
- 0 °C · <0°C
- Boiling point
- 103 · 103-104 °C5 mm Hg(lit.)
- Density
- 1.073 g/mL · 1.073 g/mL at 25 °C(lit.)
- vapor pressure
- 1.2 Pa · 1.2Pa at 20℃
- refractive index
- 20 · n20/D 1.409(lit.)
- Flash point
- 228 °F · 228 °F
- form
- Liquid
- Specific Gravity
- 1.09 · 1.09
- color
- Colorless
- Hydrolytic Sensitivity
- 7 · 7: reacts slowly with moisture/water
- InChI
- InChI=1S/C8H22O6Si2/c1-9-15(10-2,11-3)7-8-16(12-4,13-5)14-6/h7-8H2,1-6H3
- InChIKey
- JCGDCINCKDQXDX-UHFFFAOYSA-N
- SMILES
- CO[Si](OC)(OC)CC[Si](OC)(OC)OC
- LogP
- -1.68 at · -1.68 at 25℃
- CAS DataBase Reference
- 18406 · 18406-41-2(CAS DataBase Reference)
- FDA UNII
- 836 PHD3 · LJZ836PHD3
- EPA Substance Registry System
- 2 · 2,7-Dioxa-3,6-disilaoctane, 3,3,6,6-tetramethoxy- (18406-41-2)
- UNSPSC Code
- 12352103 · 12352103
- NACRES
- 23 · NA.23
- Symbol(GHS)
- 6 · GHS06
- Signal word
- Danger
- Hazard statements
- 330 · H330
- Precautionary statements
- 304 · P304+P340+P310
- PPE
- Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
- Hazard Codes
- T+
- Risk Statements
- 26 · 26
- Safety Statements
- 23 · 23-36/37-45
- RIDADR
- 3382 · UN 3382 6.1/PG 1
- WGK Germany
- 3 · 3
- RTECS
- 7873000 · JG7873000
- TSCA
- TSCA listed
- HazardClass
- 6.1 · 6.1
- HS Code
- 29319090 · 29319090
- Storage Class
- 6.1 A · 6.1A - Combustible acute toxic Cat. 1 and 2very toxic hazardous materials
- Hazard Classifications
- 1 Inhalation · Acute Tox. 1 Inhalation
- REACH Registrations
- Inactive
Safety & regulation
GHS classification
GHS Classification
Danger
H301 (10.1%): Toxic if swallowed [Danger Acute toxicity, oral]
P203, P260, P264, P270, P271, P273, P280, P284, P301+P316, P301+P317, P302+P352, P304+P340, P316, P318, P320, P321, P330, P332+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 217 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information
Chemical: 2,7-Dioxa-3,6-disilaoctane, 3,3,6,6-tetramethoxy-
Status: Cease Manufacture Update: 25-07-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/25063
1,2-Bis (trimethoxysilyl) ethane: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Hazards Summary
Prolonged or repeated contact with the skin of rabbits causes marked to severe redness, mild swelling, and superficial necrosis; Acute and short-term inhalation studies of experimental animals demonstrate severe mucous membrane damage and epithelial necrosis of the cornea and respiratory tract at concentrations as low as 0.5 ppm; [EPA TSCATS] May cause irritation; May cause pneumonitis and pulmonary edema; May be fatal by inhalation; Targets the eye, kidney, liver, heart, and nerves; [Aldrich MSDS] Produces methanol on contact with moisture or water in the skin, eyes, and mucous membranes leading to irritation and dehydration of overexposed tissue; A severe eye irritant that may cause permanent injury including blindness; A pulmonary toxin that may cause lung injury from overexposure; [Gelest MSDS] See Trimethoxysilane.
Toxicology
Safety data
- PPE
- Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
- wgk
- 3
- tsca
- TSCA listed
- rtecs
- JG7873000
- ridadr
- UN 3382 6.1/PG 1
- hs_code
- 29319090
- risk_code
- 26
- Signal word
- Danger
- Symbol(GHS)
- GHS06
- hazard_code
- T+
- safety_code
- 23-36/37-45
- hazard_class
- 6.1
- Storage Class
- 6.1A - Combustible acute toxic Cat. 1 and 2very toxic hazardous materials
- Hazard statements
- H330
- REACH Registrations
- Inactive
- Hazard Classifications
- Acute Tox. 1 Inhalation
- Precautionary statements
- P304+P340+P310
Chemistry & industry
Uses & manufacturing
Applications
Uses3,3,6,6-Tetramethoxy-2,7-dioxa-3,6-disilaoctane is useful in the preparation of functionalized periodic mesoporous organosilicas for selective adsorption of proteins.
Suppliers100 total
Related reactions
Compound notes
Loading…