Basic information
- CAS
18643-08-8- Standard SMILES
CCCCCCCCCCCCCCCCCC[Si](C)(C)Cl- InChIKey
GZGREZWGCWVAEE-UHFFFAOYSA-N- Molecular formula
- C20H43ClSi
- Average molar mass
- 347.1 g/mol
- Monoisotopic mass
- 346.28225559
Names & identifiers
- Preferred name
- Octadecyldimethylchlorosilane
- IUPAC
- chloro-dimethyl-octadecylsilane
- English name
- Chlorodimethyloctadecylsilane
- Molecular formula
- C20H43ClSi
- Molecular weight
- 347.09
Names & synonyms
Chlorodimethyloctadecylsilane18643-08-8OctadecyldimethylchlorosilaneSilane, chlorodimethyloctadecyl-LH5E2W2ASNDTXSID3066394RefChem:167714DTXCID8035891242-472-2Dimethyloctadecylchlorosilanechlorodimethyl(octadecyl)silaneChloro-dimethyl-octadecylsilane
Show more names
DK193DK642CD5636SILANE ODM2STEARYLDIMETHYLCHLOROSILANEOctadecylchlorodimethylsilane
n-OctadecyldimethylchlorosilaneChloro(dimethyl)octadecylsilaneMFCD00000504C20H43ClSichlorodimethyl-n-octadecylsilaneDimethyl-n-octadecylchlorosilaneEINECS 242-472-2CDOS
Database identifiers
- CAS
18643-08-8- PubChem CID
- 87738
- DTXSID
DTXSID3066394- UNII
- LH5E2W2ASN
- EC Number
- 242-472-2
- Nikkaji
- J149.983A
Properties
Computed structural properties
- Topological polar surface area
- 0 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 0
- Rotatable bonds
- 17
- Heavy atoms
- 22
- Formal charge
- 0
- Complexity
- 216
Experimental & physicochemical properties
Physical DescriptionLiquid
Physicochemical properties
- Melting point
- 28 · 28-31 °C
- Boiling point
- 145 · 145-155 °C0.005 mm Hg(lit.)
- Density
- 0.86 g/mL · 0.86 g/mL at 20 °C(lit.)
- vapor pressure
- 0 · 0-4220000Pa at 20-25℃
- refractive index
- 1.453 · 1.4530
- Flash point
- 230 °F · >230 °F
- storage temp.
- Store at room temperature, keep dry and cool
- form
- Solid
- Specific Gravity
- 0.854 · 0.854
- color
- White
- Water Solubility
- Reacts with water.
- Sensitive
- Moisture Sensitive
- Hydrolytic Sensitivity
- 8 · 8: reacts rapidly with moisture, water, protic solvents
- BRN
- 2246012 · 2246012
- InChI
- 1S/C20H43ClSi/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-22(2,3)21/h4-20H2,1-3H3
- InChIKey
- GZGREZWGCWVAEE-UHFFFAOYSA-N
- SMILES
- CCCCCCCCCCCCCCCCCC[Si](C)(C)Cl
- LogP
- 9 · 9
- CAS DataBase Reference
- 18643 · 18643-08-8(CAS DataBase Reference)
- FDA UNII
- 5 E2W2ASN · LH5E2W2ASN
- EPA Substance Registry System
- Silane, chlorodimethyloctadecyl- (18643-08-8)
- UNSPSC Code
- 12352001 · 12352001
- NACRES
- 22 · NA.22
- Symbol(GHS)
- 5 · GHS05,GHS07
- Signal word
- Danger
- Hazard statements
- 314 · H314-H335
- Precautionary statements
- 260 · P260-P271-P280-P301+P330+P331-P303+P361+P353-P305+P351+P338
- target organs
- Respiratory system
- PPE
- 3 · Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
- Hazard Codes
- C,F
- Risk Statements
- 34 · 34-67-65-63-48/20-11-10
- Safety Statements
- 26 · 26-36/37/39-45-62
- RIDADR
- 2987 · UN 2987 8/PG 2
- WGK Germany
- 2 · 2
- F
- 10 · 10-21
- TSCA
- TSCA listed
- HazardClass
- 8 · 8
- PackingGroup
- III
- HS Code
- 29319090 · 29319090
- Storage Class
- 8 A · 8A - Combustible corrosive hazardous materials
- Hazard Classifications
- 1 BSTOT · Skin Corr. 1BSTOT SE 3
- REACH Registrations
- Active
- Excepted Quantities
- Not Permitted as Excepted Quantity
Safety & regulation
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 6.9% (4 of 58) of reports.
Danger
H314 (93.1%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
P260, P264, P264+P265, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P363, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 58 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information
Chemical: Silane, chlorodimethyloctadecyl-
Silane, chlorodimethyloctadecyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Silane, chlorodimethyloctadecyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
REACH registered substance: Chlorodimethyloctadecylsilane (EC: 242-472-2)
Hazard Classes and CategoriesSkin Corr. 1B (93.1%)
Safety data
- F
- 10-21
- PPE
- Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
- wgk
- 2
- tsca
- TSCA listed
- ridadr
- UN 2987 8/PG 2
- hs_code
- 29319090
- risk_code
- 34-67-65-63-48/20-11-10
- Signal word
- Danger
- Symbol(GHS)
- GHS05,GHS07
- hazard_code
- C,F
- safety_code
- 26-36/37/39-45-62
- hazard_class
- 8
- Storage Class
- 8A - Combustible corrosive hazardous materials
- packing_group
- III
- target organs
- Respiratory system
- Hazard statements
- H314-H335
- Excepted Quantities
- Not Permitted as Excepted Quantity
- REACH Registrations
- Active
- Hazard Classifications
- Skin Corr. 1BSTOT SE 3
- Precautionary statements
- P260-P271-P280-P301+P330+P331-P303+P361+P353-P305+P351+P338
Chemistry & industry
Uses & manufacturing
U.S. Production2023: <50,000 lb
Industry UsesOther
General Manufacturing Information
Pharmaceutical and Medicine Manufacturing
Silane, chlorodimethyloctadecyl-: ACTIVE
Applications
UsesChlorodimethyl-n-octadecylsilane is used for preparation of hydrophobic surfaces and chain terminator.
UsesSilylating reagent
Suppliers100 total
国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
郑州阿尔法化工有限公司+86-18530059196 · [email protected]
Shandong chuangyingchemical Co., Ltd.18853181302 · [email protected]
湖北科孚乐材料科技有限公司027-84459282 13720265353 · [email protected]
湖北万得化工有限公司15377098680 15377098680 · [email protected]
武汉欣扬瑞和化学科技有限公司13720274133 · [email protected]
温州共赢化学有限公司+86-0086-577-64498589 +86-15355981851 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
陕西缔都新材料有限公司029-63373950 17392216152 · [email protected]
江苏星科元信息科技有限公司400-605-7200 15335295587
爱斯特（成都）生物制药股份有限公司+86-28-85122536 85324413 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
毕佳索（上海毕得医药科技股份有限公司）400-6005915 · [email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
北京索莱宝科技有限公司010-50973130 17801761073 · [email protected]
阿法埃莎（中国）化学有限公司400-6106006 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
上海常丰生物医药科技有限公司+86-021-61727342 13611721451 · [email protected]
上海沛诺生物技术有限公司021-58648778 18217200601;15861463695 · [email protected]
山东西亚化学有限公司13355009207 13355009207 · [email protected]
玛雅试剂+86 (573) 82222445 (0)18006601000 452520369 · [email protected]
四川库利南科技有限公司400-1166-196 18981987031 · [email protected]
Novel Chemical+86-21-64855560, 4008207808 · [email protected]
湖南汇百侍生物科技有限公司0731-85526065 13308475853 · [email protected]
南京化学试剂股份有限公司025-58369808 17895012682 · [email protected]
上海祈铭新材料有限公司021-36010885 13661599081;13701898138 · [email protected]
QINGDAO KAIENSI INTERNATIONAL TRADE CO.,LTD.+86-0532-8699-9256 +86-18518128472 · [email protected]
江苏艾康生物医药研发有限公司025-66113011 13913916777 · [email protected]
TCI AMERICA800-4238616 · [email protected]
TOKYO CHEMICAL INDUSTRY CO., LTD.03-36680489 · [email protected]
TCI Europe320-37350700 · [email protected]
中山海泓药业有限公司0760-86925768 18824993998
上海毕得医药科技股份有限公司400-164-7117 18317119277 · [email protected]
上海探圭新材料科技有限公司18516111942 · [email protected]
南通嘉星泰生物科技有限公司18795782766 · [email protected]
上海石洋化工有限公司021-56795766 · [email protected]
成都零六生物科技有限公司400-1166-196 13458535857 · [email protected]
上海麦克林生化科技股份有限公司15221275939 15221275939 · [email protected]
Sigma-Aldrich西格玛奥德里奇(上海)贸易有限公司021-61415566 800-8193336 · [email protected]
铜陵恒优生物科技有限公司021-50426030 13856289449;13124863828 · [email protected]
Shanghai Enchem Industry Co., Ltd.15021317485
壮铭新材料科技江苏有限公司17312398916 051386936896 15216715905 · [email protected]
湖北军瑞生物科技有限公司13971166412 · [email protected]
广东翁江化学试剂有限公司0751-2886766 13927870850 · [email protected]
嘉兴市德亿化工有限公司0573-85866609 13325730825 · [email protected]
上海珈得尔化学技术有限公司021-4007787-550 400-7787-550 · [email protected]
上海阿拉丁生化科技股份有限公司6206333 13167063860 · [email protected]
上海岚克医药科技发展有限公司0086-21-58956006
Related reactions
5 records
Compound notes
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