CAS 19841-73-7 4-Benzhydrylpiperidine (HCID 88278)

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Basic information

CAS: 19841-73-7
Standard SMILES: c1ccc(C(c2ccccc2)C2CCNCC2)cc1
InChIKey: LUYLEMZRJQTGPM-UHFFFAOYSA-N
Molecular formula: C18H21N
Average molar mass: 251.4 g/mol
Monoisotopic mass: 251.16739967

Overview

structure given in first source; has ability to reduce insulin in young rats

Names & identifiers

Preferred name: 4-Benzhydrylpiperidine
IUPAC: 4-benzhydrylpiperidine
English name: 4-(diphenylmethyl)piperidine
Molecular formula: C18H21N
Molecular weight: 251.37

Names & synonyms

4-benzhydrylpiperidine19841-73-74-DiphenylmethylpiperidinePiperidine, 4-(diphenylmethyl)-WF8WX7G0SRNSC-89763DTXSID0066539RWJ-43724RefChem:987824-DPMPDTXCID1036173243-365-3

Show more names

4-(Diphenylmethyl)piperidineNSC 89763; RWJ 43724; 4-BenzhydrylpiperidineEINECS 243-365-3NSC 89763BRN 02059594-benzhydryl-piperidineUNII-WF8WX7G0SR4-diphenylmethyl-piperidine

Database identifiers

CAS: 19841-73-7
PubChem CID: 88278
DTXSID: DTXSID0066539
ChEMBL: CHEMBL3770298
UNII: WF8WX7G0SR
EC Number: 243-365-3
Nikkaji: J50.660E

Properties

Computed structural properties

XLogP: 4
Topological polar surface area: 12 Å²
Hydrogen bond donors: 1
Hydrogen bond acceptors: 1
Rotatable bonds: 3
Heavy atoms: 19
Formal charge: 0
Complexity: 226

Physicochemical properties

Melting point: 99 °C · 99 °C
Boiling point: 384.53 °C · 384.53°C (rough estimate)
Density: 0.8635 · 0.8635 (rough estimate)
refractive index: 1.532 · 1.5320 (estimate)
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 10.47 · 10.47±0.10(Predicted)
color: White to Off-White
FDA UNII: 8 WX7G0SR · WF8WX7G0SR
EPA Substance Registry System: 4 · Piperidine, 4-(diphenylmethyl)- (19841-73-7)
Symbol(GHS): 7 · GHS07,GHS05
Signal word: Danger
Hazard statements: 302 · H302-H335-H318-H315
Precautionary statements: 264 · P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P280-P305+P351+P338-P310
TSCA: TSCA listed

Safety & regulation

GHS classification

GHS Classification · 4 items

Danger

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P330, P332+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Hazard information

Hazard Classes and CategoriesAcute Tox. 4 (100%)

Safety data

tsca: TSCA listed
Signal word: Danger
Symbol(GHS): GHS07,GHS05
Hazard statements: H302-H335-H318-H315
Precautionary statements: P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P280-P305+P351+P338-P310

Chemistry & industry

Uses & manufacturing

General Manufacturing InformationPiperidine, 4-(diphenylmethyl)-: INACTIVE

Applications

Uses4-Diphenylmethylpiperidine, is an intermediate in the synthesis of more complex pharmaceutical and biologically active compounds. It can be used in the synthesis of diphenyl lactam derivatives as N-type calcium channel blockers.