HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dipropylamine
DPA · DI-N-PROPYLAMINE · DNPA · N-Propylpropan-1-amine · n,n-dipropylamine · ai3-24037 · (n-C3H7)2NH · Di-n-propyL
Identifiers & Physical Properties
| CAS No. | 142-84-7 |
|---|---|
| Molecular formula | C6H15N |
| Average molar mass | 101.19 g/mol |
| Monoisotopic mass | 101.12044948 g/mol |
| SMILES | CCCNCCC |
| InChIKey | WEHWNAOGRSTTBQ-UHFFFAOYSA-N |
| PubChem CID | 8902 |
| ChEMBL | CHEMBL3185961 |
| EC No. | 205-565-9 |
| DTXSID | DTXSID2025185 |
Chemical & Physical Properties
| XLogP | 1.7 |
|---|---|
| Topological polar surface area | 12 |
| Hydrogen bond donors | 1 |
| Hydrogen bond acceptors | 1 |
| Rotatable bonds | 4 |
| Heavy atoms | 7 |
| Formal charge | 0 |
| Complexity | 23.4 |
| Chemical classes | Nitrogen Compounds -> Amines, AliphaticFlammable agents - 3rd degree |
| PFAS | PFAS -> Other/unspecified |
| SpringerMaterials Properties | Boiling point |
| LogP (partition coefficient) | log Kow = 1.671.73 |
| Odor | Ammonia odor |
| Density | 0.738 at 68 °F (USCG, 1999) - Less dense than waterwill float0.738 at 20 °C/4 °CBulk density = 6.1 lb/galSaturated liquid density= 46.010 lb/cu ft @ 70 °CSaturated vapor density= 0.00771 lb/cu ft @ 70 °C0.7400 @ 20°C0.738 g/mL at 25 °C(lit.) |
| Viscosity | 0.517 mPa.s at 25 °C |
| Color/Form | Colorless liquidWater-white liquid |
| Solubility | Soluble (>=10 mg/ml) (NTP, 1992)Miscible in ether, very soluble in acetone, soluble in ethanolIn water, 3.51X10+4 mg/L at 25 °C35g/l (experimental) |
| Flash point | 45 °F (USCG, 1999)63 °F (17 °C) (open cup)7 °C (closed cup)39 °F |
| Boiling point | 228.9 °F at 760 mmHg (NTP, 1992)109.3 °C109.3 °C @760 [mm Hg]105-110 °C(lit.) |
| Decomposition | When heated to decomposition it emits toxic fumes of nitroxides. |
| Melting point | -63 °C |
| Vapor pressure | 38 hPa (20 °C) |
| Refractive index | n20/D 1.4049(lit.) |
| Storage conditions | Store below +30°C. |
| pKa (acidity coefficient) | pK1:10.91(+1) (25°C) |
| Physical state | Liquid |
| Color | Clear |
| Explosive limits | 1.8-9.3%(V) |
| Merck | 14,3343 |
| BRN | 505974 |
| Henry's law constant | 2.0×10-1 mol/(m3Pa) at 25℃, Burkholder et al. (2019) |
| Dielectric constant | 2.9(21℃) |
| Stability | Stable. Highly flammable. Incompatible with strong oxidizing agents. |
| InChI | 1S/C6H15N/c1-3-5-7-6-4-2/h7H,3-6H2,1-2H3 |
| InChIKey | WEHWNAOGRSTTBQ-UHFFFAOYSA-N |
| SMILES | CCCNCCC |
| LogP (partition coefficient) | 1.33 at 23℃ |
| Dissociation constant | 11 |
| CAS DataBase Reference | 142-84-7(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 60P318IIRY |
| NIST Chemistry Reference | 1-Propanamine, n-propyl-(142-84-7) |
| EPA Substance Registry System | Dipropylamine (142-84-7) |
| UNSPSC Code | 12352116 |
| NACRES | NA.22 |
| GHS pictogram | GHS02,GHS05,GHS06,GHS08 |
| Signal word | Danger |
| GHS hazard statements | H311+H331-H302-H314-H371-H370-H335-H225 |
| GHS precautionary statements | P501-P270-P240-P260-P210-P233-P243-P241-P242-P271-P264-P280-P370+P378-P308+P311-P361+P364-P303+P361+P353-P301+P330+P331-P301+P312+P330-P304+P340+P310-P305+P351+P338+P310-P403+P233-P403+P235-P405 |
| Target organs | Respiratory system |
| Personal protective equipment (PPE) | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter |
| Hazard symbols | F,C |
| Risk statements (R) | 11-20/21/22-35 |
| Safety statements (S) | 16-26-36/37/39-45 |
| UN transport number | UN 2383 |
| Water hazard class (WGK) | 1 |
| RTECS number | JL9200000 |
| Autoignition temperature | 260 °C |
| TSCA inventory status | TSCA listed |
| Hazard class | 3Acute Tox. 3 DermalAcute Tox. 3 InhalationAcute Tox. 4 OralEye Dam. 1Flam. Liq. 2Skin Corr. 1ASTOT SE 3 |
| Packing group | II |
| Customs code | 29211910 |
| Storage class | 3 - Flammable liquids |
| Hazardous substances data | 142-84-7(Hazardous Substances Data) |
| Toxicity | LD50 orally in rats: 0.93 g/kg, H. F. Smyth et al., Am. Ind. Hyg. Assoc. J. 23, 95 (1962) |
| REACH registrations | Active |
| Limited quantities | 1.0 L (0.3 gallon) (liquid) |
| Excepted quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) |
Safety & Regulations
| GHS classification | DangerH225: Highly Flammable liquid and vapor [Danger Flammable liquids]P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P321, P330, P362+P364, P363, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement)H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]P210, P233, P240, P241, P242, P243, P260, P261, P262, P264, P264+P265, P270, P271, P280, P301+P316, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P319, P321, P330, P361+P364, P362+P364, P363, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement) |
|---|---|
| Regulatory information | Chemical: 1-Propanamine, N-propyl-1-Propanamine, N-propyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1-Propanamine, N-propyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 05-10-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/138191-Propanamine, N-propyl-: HSNO Approval: HSR001143 Approved with controlsThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| Other safety information | IMAP assessments - Short chain (C2-3) alkyl amines: Human health tier II assessment |
| DOT label | Flammable Liquid Corrosive |
| Fire hazards | Special Hazards of Combustion Products: Toxic oxides of nitrogen may form in fires. (USCG, 1999)· Flammable/combustible material. |
| Fire potential | Forms explosive mixture with air.A very dangerous fire hazard when exposed to heat or flame. |
| Health hazards | Inhalation causes severe coughing and chest pain due to irritation of air passagescan-cause lung edema |
Applications & Uses
Description
Dipropylamine is a colorless, water-white liquid with a strong ammonia-like odor. Molecularweight= 101.22; Boiling point = 110℃; Freezing/Meltingpoint = 263℃; Vapor pressure= 29.8 mmHg at 25℃;Flash point = 17℃; Autoignition temperature= 299℃.Hazard Identification (based on NFPA-704 M RatingSystem): Health 3, Flammability 4, Reactivity 1. Insolublein water
Uses
n-Dipropylamine is a useful reagent for the preparation of perylene derivatives for photosensitive fluorescent resins.
General Description
A clear colorless liquid with an ammonia-like odor. Flash point 30°F. Less dense than water. Vapors heavier than air. Toxic oxides of nitrogen produced during combustion.