Basic information
- CAS
22705-33-5- Standard SMILES
CN(C)[SiH](C)N(C)C- InChIKey
VBYLGQXERITIBP-UHFFFAOYSA-N- Molecular formula
- C5H16N2Si
- Average molar mass
- 132.28 g/mol
- Monoisotopic mass
- 132.10827505
Names & identifiers
- Preferred name
- N,N,N',N',1-Pentamethylsilanediamine
- IUPAC
- N-[dimethylamino(methyl)silyl]-N-methylmethanamine
- English name
- Bis(dimethylamino)methylsilane
- Molecular formula
- C5H16N2Si
- Molecular weight
- 132.28
Names & synonyms
RefChem:35858922705-33-5N,N,N',N',1-Pentamethylsilanediaminebis(dimethylamino)-methylsilaneC5H16N2SiN-[dimethylamino(methyl)silyl]-N-methylmethanamineSCHEMBL258875VBYLGQXERITIBP-UHFFFAOYSA-NN-[dimethylamino(methyl)silyl]-N-methyl-methanamineBDMAMSDK223Bis(dimethylamino)methylsilane
Show more names
n,n,n’,n’,1-pentamethyl-silanediaminN,N,N',N',α-PentamethylsilanediamineN,N,N’,N’,1-pentamethyl-SilanediamineSilanediamine,N,N,N',N',1-pentamethyl-
Database identifiers
- CAS
22705-33-5- PubChem CID
- 89797
- DTXSID
DTXSID80885211- EC Number
- 245-163-0
Properties
Computed structural properties
- Topological polar surface area
- 6.5 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 2
- Heavy atoms
- 8
- Formal charge
- 0
- Complexity
- 55.4
Physicochemical properties
- Melting point
- 0 °C · <0°C
- Boiling point
- 112 °C · 112 °C
- Density
- 0.798 g/mL · 0.798 g/mL at 20 °C(lit.)
- refractive index
- 20 · n20/D 1.414
- Flash point
- -3 °C · -3°C
- pka
- 10.24 · 10.24±0.70(Predicted)
- Specific Gravity
- 0.798 · 0.798
- Hydrolytic Sensitivity
- 9 · 9: reacts extremely rapidly with atmospheric moisture - may be pyrophoric - glove box or sealed system required
- InChI
- InChI=1S/C5H16N2Si/c1-6(2)8(5)7(3)4/h8H,1-5H3
- InChIKey
- VBYLGQXERITIBP-UHFFFAOYSA-N
- SMILES
- [SiH](C)(N(C)C)N(C)C
- EPA Substance Registry System
- 1 · Silanediamine, N,N,N',N',1-pentamethyl- (22705-33-5)
- Symbol(GHS)
- 2 · GHS02,GHS05
- Signal word
- Danger
- Hazard statements
- 225 · H225-H314
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]
P210, P223, P231+P232, P233, P240, P241, P242, P243, P260, P264, P264+P265, P280, P301+P330+P331, P302+P335+P334, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P321, P363, P370+P378, P402+P404, P403+P235, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 74 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazard Classes and CategoriesFlam. Liq. 2 (100%)
Safety data
- F
- 10-21
- wgk
- 3
- tsca
- TSCA listed
- ridadr
- UN 2924 3/PG 2
- risk_code
- 11-34
- Signal word
- Danger
- Symbol(GHS)
- GHS02,GHS05
- hazard_code
- F,C
- safety_code
- 16-26-36/37/39-45
- Hazard statements
- H225-H314
- Precautionary statements
- P210-P280-P305+P351+P338-P310
Chemistry & industry
Applications
DescriptionBis(dimethylamino)methylsilane is used as a reagent in the pharmaceutical industry, primarily in silanation reactions.
UsesBis(dimethylamino)methylsilane can be used as a protecting group for reactive hydrogens in alcohols, amines, thiols, and carboxylic acids. Organosilanes are hydrogen-like, can be introduced in high yield, and can be removed under selective conditions. They are stable over a wide range of reaction conditions and can be removed in the presence of other functional groups, including other protecting groups.
Suppliers37 total
湖北永阔科技有限公司027-59223108 15972152991 · [email protected]
温州共赢化学有限公司+86-0086-577-64498589 +86-15355981851 · [email protected]
湖南嘉航医药科技有限公司85521272 18229978283 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
北京华威锐科化工有限公司0757-86329057 18934348241 · [email protected]
Nantong Honglong Chemical Co., Ltd+86-86-13078814179 +8619052560825 · [email protected]
广东云星生物技术有限公司0751-18902340975/189023400307 18902340307 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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