Vitride
Basic information
- CAS
22722-98-1- Standard SMILES
COCC[O-].COCC[O-].[AlH2+].[Na+]- InChIKey
XJIQVZMZXHEYOY-UHFFFAOYSA-N- Molecular formula
- C6H16AlO4.Na
- Average molar mass
- 202.16 g/mol
- Monoisotopic mass
- 202.0761667
Overview
Sodium bis(2-methoxyethoxy)aluminumhydride, also called Red-Al, is an organoaluminium compound. It is used as a reagent in organic synthesis. Aluminum is the most abundant metal in the earth's crust and is always found combined with other elements such as oxygen, silicon, and fluorine. (L739, L740, L777)
Names & identifiers
- Preferred name
- Vitride
- IUPAC
- sodium;alumanylium;bis(2-methoxyethanolate)
- English name
- Sodium bis(2-methoxyethoxy)aluminiumhydride
- Molecular formula
- C6H16AlNaO4
- Molecular weight
- 202.16
Names & synonyms
Aluminate(1-), dihydrobis(2-(methoxy-kappaO)ethanolato-kappaO)-, sodiumSMEAHRefChem:887319245-178-204JL3B71VP22722-98-1Sodium bis(2-methoxyethoxy)aluminum hydrideVitridesodium;alumanylium;2-methoxyethanolateAluminate(1-), dihydrobis(2-(methoxy-kappaO)ethanolato-kappaO)-, sodium (1:1)Sodium bis(2-methoxyethoxy)aluminium hydride 70% in tolueneRED-AL
Show more names
Red aluminumSODIUM BIS(2-METHOXYETHOXY)ALUMINIUM HYDRIDESBAHbis(2-Methoxyethoxy)aluMinuM(III) sodiuM hydrideSODIUM BIS(2-METHOXYETHOXY)ALUMINUM DIHYDRIDESynhydrid
Database identifiers
- CAS
22722-98-1- PubChem CID
- 89806
Properties
Computed structural properties
- Topological polar surface area
- 64.6 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 4
- Heavy atoms
- 12
- Formal charge
- 0
- Complexity
- 14.4
Experimental & physicochemical properties
Chemical ClassesMetals -> Organic Compounds, Metal Salts
Physical Description
Liquid
Viscous liquid; [Merck Index]
Physicochemical properties
- Boiling point
- 396 · 396-402°C
- Density
- 1.036 g/mL · 1.036 g/mL at 25 °C
- vapor pressure
- 21 mm · 21 mm Hg ( 20 °C)
- Flash point
- 40 °F · 40 °F
- storage temp.
- Flammables area
- solubility
- Miscible with aromatic hydrocarbons, ether, tetrahydrofuran, dimethyl ether and dimethylformamide. Immiscible with aliphatic hydrocarbons.
- form
- Viscous Liquid
- color
- Clear to slightly hazy, colorless to light amber
- Specific Gravity
- 1.036 · 1.036
- explosive limit
- 7 % · 7%
- Water Solubility
- reacts
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 17.3% (37 of 214) of reports.
Danger
H228 (26.6%): Flammable solid [Danger Flammable solids]
P210, P223, P231+P232, P240, P241, P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P301+P330+P331, P302+P335+P334, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P319, P321, P330, P362+P364, P363, P370+P378, P402+P404, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 214 reports by companies from 13 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Not Classified
Hazard information
Regulatory Information
Chemical: Aluminate(1-), dihydrobis(2-methoxyethanolato-O,O')-, sodium
Aluminate(1-), dihydrobis[2-(methoxy-.kappa.O)ethanolato-.kappa.O]-, sodium (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Aluminate(1-), dihydrobis[2-(methoxy-.kappa.O)ethanolato-.kappa.O]-, sodium (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
REACH registered substance: Sodium dihydridobis(2-methoxyethanolato)aluminate(1-) (EC: 245-178-2)
Other Safety InformationIMAP assessments - Aluminate(1-), dihydrobis(2-methoxyethanolato-O,O')-, sodium: Environment tier I assessment
Hazards Summary
70% Toluene solution: Pyrophoric; Reacts violently with water evolving flammable gases; Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; Harmful by inhalation; [Alfa Aesar MSDS] See Aluminum hydride.
Chemistry & industry
Pharmacology
Metabolism/Metabolites
Aluminum is poorly absorbed following either oral or inhalation exposure and is essentially not absorbed dermally. The bioavailability of aluminum is strongly influenced by the aluminum compound and the presence of dietary constituents which can complex with aluminum and enhance or inhibit its absorption. Aluminum binds to various ligands in the blood and distributes to every organ, with highest concentrations found in bone and lung tissues. In living organisms, aluminum is believed to exist in four different forms: as free ions, as low-molecular-weight complexes, as physically bound macromolecular complexes, and as covalently bound macromolecular complexes. Absorbed aluminum is excreted principally in the urine and, to a lesser extent, in the bile, while unabsorbed aluminum is excreted in the faeces. (L739)
Uses & manufacturing
Uses
Used as a reducing agent; [Merck Index]
Sodium bis(2-methoxyethoxy)aluminumhydride is used as a reagent in organic synthesis. (L777)
U.S. Production2023: 500,000 - <1,000,000 lb
Industry UsesReducing agent
General Manufacturing Information
All Other Basic Organic Chemical Manufacturing
Aluminate(1-), dihydrobis[2-(methoxy-.kappa.O)ethanolato-.kappa.O]-, sodium (1:1): ACTIVE
Applications
UsesReducing agent.
UsesRed-Al sodium bis(2-methoxyethoxy)aluminum hydride can be used as: A tosyl deprotecting agent.A catalyst for crosslinking of polyvinylsilanes (PVS) by Si-Si dehydrocoupling reaction in the presence of group 4 metallocene complexes.A reducing reagent for the synthesis of optically active N-protected amino alcohols and peptide alcohols.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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