Basic information
- CAS
25334-23-0- Standard SMILES
Cl.NC(=O)c1cccnc1- InChIKey
OBLVPWTUALCMGD-UHFFFAOYSA-N- Molecular formula
- C6H7ClN2O
- Average molar mass
- 158.58 g/mol
- Monoisotopic mass
- 158.0246905
Names & identifiers
- Preferred name
- 3-Pyridinecarboxamide, hydrochloride (1:1)
- IUPAC
- pyridine-3-carboxamide;hydrochloride
- English name
- Nicotinamide hydrochloride
- Molecular formula
- C6H7ClN2O
- Molecular weight
- 158.59
Names & synonyms
NIACINAMIDE HYDROCHLORIDE25334-23-0Nicotinamide HCl4D16EOF1QWDTXSID00179982RefChem:1068656DTXCID601024733-Pyridinecarboxamide, hydrochloride (1:1)246-862-3Nicotinamide hydrochloridepyridine-3-carboxamide;hydrochlorideNiacinamide (Hydrochloride)
Show more names
NICA-001nicotinamideHClOBLVPWTUALCMGD-UHFFFAOYSA-NNicotinic acid amide HydrochlorideNiacinamide Hydrochloride|||Nicotinic acid amide Hydrochloride|||Niacinamide Hydrochloride
Nicotinamide (Hydrochloride)3-Pyridinecarboxamide, monohydrochloride (9CI); Nicotinamide, monohydrochloride (8CI)UNII-4D16EOF1QWEINECS 246-862-3orb1745074SCHEMBL1220080SCHEMBL29440773HY-B0150A
Database identifiers
- CAS
25334-23-0- PubChem CID
- 91408
- DTXSID
DTXSID00179982- UNII
- 4D16EOF1QW
- EC Number
- 246-862-3
Properties
Computed structural properties
- Topological polar surface area
- 56 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 1
- Heavy atoms
- 10
- Formal charge
- 0
- Complexity
- 114
Physicochemical properties
- FDA UNII
- 4 D16EOF1QW · 4D16EOF1QW
Chemistry & industry
Applications
UsesNicotinamide Hydrochloride is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide Hydrochloride also inhibits SIRT1. Nicotinamide Hydrochloride increases cellular NAD+, ATP, ROS levels. Nicotinamide Hydrochloride inhibits tumor growth and improves survival. Nicotinamide Hydrochloride also has anti-HBV activity[1][2][3][4].
Upstream & downstream products
Downstream products
Suppliers6 total
长沙晶康新材料科技有限公司0733-0731-85118349 18229890050 · [email protected]
上海威尔舒氪医药科技有限公司15250615384
上海陶术生物科技股份有限公司13564774135 · [email protected]
上海策嵘生物科技有限公司（定制合成实验室）13062833949 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
DAYANG CHEM (HANGZHOU) CO.,LTD+86-88938639 +86-17705817739 · [email protected]
Related reactions
1 records
Compound notes
Loading…