Basic information
- CAS
56932-43-5- Standard SMILES
O=S(=O)([O-])c1ccc2cc(N=Nc3cc(S(=O)(=O)[O-])c4cccnc4c3O)ccc2c1.[Na+].[Na+]- InChIKey
IFVGQKHFUZRWNA-UHFFFAOYSA-L- Molecular formula
- C19H11N3Na2O7S2
- Average molar mass
- 503.4 g/mol
- Monoisotopic mass
- 502.98338061
Names & identifiers
- Preferred name
- 5-Quinolinesulfonic acid, 8-hydroxy-7-[2-(6-sulfo-2-naphthalenyl)diazenyl]-, sodium salt (1:2)
- IUPAC
- disodium;8-hydroxy-7-[(6-sulfonatonaphthalen-2-yl)diazenyl]quinoline-5-sulfonate
- English name
- 8-Hydroxy-7-(6-sulfo-2-naphthylazo)-5-quinolinesulfonic acid disodium salt
- Molecular formula
- C19H11N3Na2O7S2
- Molecular weight
- 503.42
Names & synonyms
56932-43-5EINECS 260-449-5DTXSID308894017-(6-Sulfo-2-naphthylazo)-8-hydroxyquinoline-5-sulfonic acid, disodium salt5-Quinolinesulfonic acid, 8-hydroxy-7-((6-sulfo-2-naphthalenyl)azo)-, disodium salt5-Quinolinesulfonic acid, 8-hydroxy-7-(2-(6-sulfo-2-naphthalenyl)diazenyl)-, sodium salt (1:2)5-Quinolinesulfonic acid, 8-hydroxy-7-[(6-sulfo-2-naphthalenyl)azo]-, disodium salt5-Quinolinesulfonic acid, 8-hydroxy-7-[2-(6-sulfo-2-naphthalenyl)diazenyl]-, sodium salt (1:2)RefChem:537798DTXCID901028662NSC-87877 disodium8-Hydroxy-7-(6-sulfo-2-naphthylazo)-5-quinolinesulfonic acid disodium salt
Show more names
NSC 87877 sodiumNSC-87877(sodium salt)nsc-87877 disodium saltNSC87877/Naphthylazoxine6SNAPHTHYLAZOXINE S DISODIUM SALTNSC-87877 disodium, 10 mM in DMSOSHP1/2 PTPase Inhibitor, NSC-87877
Naphthylazoxine 6SNAPHTHYLAZOXINE SNSC87877Disodium 8-hydroxy-7-[(6-sulphonato-2-naphthyl)azo]quinoline-5-sulphonatesodium 8-hydroxy-7-((6-sulfonatonaphthalen-2-yl)diazenyl)quinoline-5-sulfonatedisodium;8-hydroxy-7-[(6-sulfonatonaphthalen-2-yl)diazenyl]quinoline-5-sulfonatedisodium 8-hydroxy-7-[(1E)-2-(6-sulfonatonaphthalen-2-yl)diazen-1-yl]quinoline-5-sulfonateCHEMBL501993
Properties
Computed structural properties
- Topological polar surface area
- 189 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 10
- Rotatable bonds
- 2
- Heavy atoms
- 33
- Formal charge
- 0
- Complexity
- 857
Physicochemical properties
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- 10 mg/mL · water: 10 mg/mL
- form
- Solid
- color
- Brown to black
- Water Solubility
- 10 mg/mL · water: 10mg/mL
- InChIKey
- YOGRUDWAJPVHEL-LLDDCTHSSA-L
- SMILES
- [Na+].[Na+].[S](=O)(=O)([O-])c1cc2c(cc(cc2)N\N=C3/C=C(c4c(nccc4)C/3=O)[S](=O)(=O)[O-])cc1
- EPA Substance Registry System
- 5 · 5-Quinolinesulfonic acid, 8-hydroxy-7-[(6-sulfo-2-naphthalenyl)azo]-, disodium salt (56932-43-5)
- UNSPSC Code
- 12352200 · 12352200
- NACRES
- 54 · NA.54
- Safety Statements
- 24 · 24/25
- WGK Germany
- 2 · WGK 2
- TSCA
- TSCA listed
- Storage Class
- 11 · 11 - Combustible Solids
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- wgk
- WGK 2
- tsca
- TSCA listed
- safety_code
- 24/25
- Storage Class
- 11 - Combustible Solids
Chemistry & industry
Uses & manufacturing
General Manufacturing Information5-Quinolinesulfonic acid, 8-hydroxy-7-[2-(6-sulfo-2-naphthalenyl)diazenyl]-, sodium salt (1:2): ACTIVE
Applications
UsesNSC-87877 disodium is a potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases (SH-PTP2 and SH-PTP1), with IC50 values of 0.318 μM, 0.355 μM shp2 and shp1, respectively[1]. NSC-87877 also inhibits dual-specificity phosphatase 26 (DUSP26)[2].
Suppliers43 total
湖北永阔科技有限公司027-59223108 15972152991 · [email protected]
湖北万得化工有限公司15377098680 15377098680 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
Nantong HI-FUTURE Biology Co., Ltd.+86-18051384581 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
United Life Science020-82099279 18988968278 · [email protected]
怀化市冰峰化工有限公司0745-2866851 17711757908 · [email protected]
銳迪國際科技有限公司18024082417 · [email protected]
北京博奥森生物技术有限公司
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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