Basic information
- CAS
298-96-4- Standard SMILES
[Cl-].c1ccc(-c2nn(-c3ccccc3)[n+](-c3ccccc3)n2)cc1- InChIKey
PKDBCJSWQUOKDO-UHFFFAOYSA-M- Molecular formula
- C19H15N4.Cl
- Average molar mass
- 334.8 g/mol
- Monoisotopic mass
- 334.0985242
Overview
2,3,5-triphenyltetrazolium chloride is an organic chloride salt having 2,3,5-triphenyltetrazolium as the counterion. It has a role as a dye and an indicator. It contains a 2,3,5-triphenyltetrazolium.
Names & identifiers
- Preferred name
- Triphenyltetrazolium chloride
- IUPAC
- 2,3,5-triphenyltetrazol-2-ium chloride
- English name
- 2,3,5-Triphenyltetrazolium chloride
- Molecular formula
- C19H15ClN4
- Molecular weight
- 334.8
Names & synonyms
2,3,5-Triphenyltetrazolium chloride298-96-4Red tetrazoliumUroscreenVitastainTRIPHENYLTETRAZOLIUM CHLORIDEUrocheckD25727K0RBNSC-5053CHEBI:78019RefChem:900031206-071-6
Show more names
TTCRTTTZTETRAZOLIUM SALTTTLred tetazolium2,3,5-TRIPHENYLTETRAZOLIUM CHLORIDE (TTC)
2H-Tetrazolium, 2,3,5-triphenyl-, chlorideTPTZTetrazolium Red2,3,5-Triphenyl-2H-tetrazolium chlorideTetrazolium chloride2,3,5-triphenyl-2h-tetrazol-3-ium chloride2,3,5-triphenyltetrazol-2-ium;chlorideTetrazole Red
Database identifiers
- CAS
298-96-4- PubChem CID
- 9283
- DTXSID
DTXSID30889340- ChEMBL
CHEMBL401540- ChEBI
CHEBI:78019- UNII
- D25727K0RB
- EC Number
- 206-071-6
Properties
Computed structural properties
- Topological polar surface area
- 34.6 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 3
- Heavy atoms
- 24
- Formal charge
- 0
- Complexity
- 330
Experimental & physicochemical properties
Chemical ClassesDyes -> Other Dyes
Physical DescriptionNearly colorless solid; Becomes yellow on light exposure; [Merck Index] Light yellow solid; [Sigma-Aldrich MSDS]
Physicochemical properties
- Melting point
- 250 °C · 250 °C(lit.)
- Boiling point
- 490.96 °C · 490.96°C (rough estimate)
- Density
- 1.1704 · 1.1704 (rough estimate)
- bulk density
- 230 kg/m3 · 230kg/m3
- refractive index
- 1.611 · 1.6110 (estimate)
- storage temp.
- 2 · 2-8°C
- solubility
- 2 O: · H2O: may be clear to slightly hazy
- form
- powder
- color
- faint yellow
- PH
- 3.7 · 3.7 (20°C, 10g/L in H2O)
- Water Solubility
- Soluble in water, ethanol and acetone. Insoluble in ether.
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H228 (63.6%): Flammable solid [Danger Flammable solids]
P210, P240, P241, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 165 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information
Chemical: 2H-Tetrazolium, 2,3,5-triphenyl-, chloride
2H-Tetrazolium, 2,3,5-triphenyl-, chloride: Does not have an individual approval but may be used under an appropriate group standard
Hazards SummaryIntravenous LD50 (mouse) = 5.6 mg/kg; [RTECS] A skin and strong eye irritant; [Sigma-Aldrich MSDS]
Hazard Classes and CategoriesFlam. Sol. 1 (63.6%)
Safety data
- F
- 3-8-10
- PPE
- dust mask type N95 (US), Eyeshields, Gloves
- wgk
- 3
- tsca
- TSCA listed
- rtecs
- XF8100000
- hs_code
- 29339900
- Toxicity
- LD50 intravenous in mouse: 5600ug/kg
- risk_code
- 36/37/38-20/21/22
- Signal word
- Danger
Chemistry & industry
Pharmacology
MeSH Pharmacological ClassificationChemicals and substances that impart color including soluble dyes and insoluble pigments. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS.
Uses & manufacturing
UsesUsed in analytical chemistry, for staining plant and animal tissues, and to test the ability of seeds to germinate; [Merck Index]
General Manufacturing Information2H-Tetrazolium, 2,3,5-triphenyl-, chloride (1:1): ACTIVE
Applications
Uses2,3,5-Triphenyl-2H-tetrazolium chloride is used as a dye in cell biological studies.
Uses2,3,5-Triphenyltetrazolium chloride is a selective serotonin 5-HT4 receptor agonist and 5-HT3 gastrointestinal prokinetic agent for functional dyspepsia
UsesIn analytical chemistry as a sensitive reagent for reducing sugars, and to distinguish between a-ketols and simple aldehydes. For staining plant and animal tissue. Germination indicator in testing the ability of seeds to germinate: G. Lakon, Ber. Dtsch. Bot. Ges. 60, 299, 434 (1942). In histochemical studies. In determination of antibiotics; of dehydrogenases.
General Description2,3,5-Triphenyltetrazolium chloride is a colorless water-soluble dye. In the mitochondria of living cells, it is reduced to a deep red, water-insoluble compound (formazan). 2,3,5-Triphenyltetrazolium chloride helps to distinguish between viable and infarcted brain tissue after stroke.
Upstream & downstream products
Upstream raw materials
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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