Clobutinol Hydrochloride
Basic information
- CAS
1215-83-4- Standard SMILES
CC(CN(C)C)C(C)(O)Cc1ccc(Cl)cc1.Cl- InChIKey
ZMROYCGIWPNZNJ-UHFFFAOYSA-N- Molecular formula
- C14H23Cl2NO
- Average molar mass
- 292.2 g/mol
- Monoisotopic mass
- 291.1156697
Overview
Clobutinol hydrochloride is a member of benzenes and an organic amino compound.
Names & identifiers
- Preferred name
- Clobutinol Hydrochloride
- IUPAC
- 1-(4-chlorophenyl)-4-(dimethylamino)-2,3-dimethylbutan-2-ol;hydrochloride
- English name
- p-chloro-alpha-[2-(dimethylamino)-1-methylethyl]-alpha-methylphenethyl alcohol hydrochloride
- Molecular formula
- C14H23Cl2NO
- Molecular weight
- 292.24452
Names & synonyms
Clobutinol hydrochloride1215-83-4SilomatClobutinol HClKAT 256DTXSID7047807N2U6799DZQp-Chloro-alpha-(2-dimethylamino-1-methylethyl)-alpha-methylphenethyl alcohol hydrochlorideDTXCID9027784KAT-256RefChem:127012214-931-7
Show more names
SilomSilonistClobutinol Hydrochloride 1.0 mg/ml in Methanol (as free base)1-p-Chlorophenyl-2,3-dimethyl-4-dimethylamino-2-butanol hydrochloride1-(4-chlorophenyl)-4-(dimethylamino)-2,3-dimethyl-butan-2-ol hydrochloridep-chloro-α-[2-(dimethylamino)-1-methylethyl]-α-methylphenethyl alcohol hydrochloride
Clobutinol (hydrochloride)Clobutinol hydrochloride [JAN]p-chloro-alpha-[2-(dimethylamino)-1-methylethyl]-alpha-methylphenethyl alcohol hydrochloride1-(4-chlorophenyl)-4-(dimethylamino)-2,3-dimethylbutan-2-ol hydrochloridePertoxil1-(4-chlorophenyl)-4-(dimethylamino)-2,3-dimethylbutan-2-ol;hydrochlorideBiotertussinPetoxil
Database identifiers
- CAS
1215-83-4- PubChem CID
- 92876
- DTXSID
DTXSID7047807- ChEMBL
CHEMBL3183114- ChEBI
CHEBI:31416- UNII
- N2U6799DZQ
- EC Number
- 214-931-7
Properties
Computed structural properties
- Topological polar surface area
- 23.5 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 5
- Heavy atoms
- 18
- Formal charge
- 0
- Complexity
- 226
Physicochemical properties
- Melting point
- 169 · 169-170°
- form
- Solid
- color
- White to off-white
- FDA UNII
- 2 U6799DZQ · N2U6799DZQ
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302
- Precautionary statements
- 264 · P264-P270-P301+P312-P330-P501
- Toxicity
- 50 in · LD50 in mice (mg/kg): 600 orally; 130 i.p. (Engelhorn)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 5 reports by companies from 2 notifications to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Safety data
- Toxicity
- LD50 in mice (mg/kg): 600 orally; 130 i.p. (Engelhorn)
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302
- Precautionary statements
- P264-P270-P301+P312-P330-P501
Chemistry & industry
Pharmacology
MeSH Pharmacological ClassificationAgents that suppress cough. They act centrally on the medullary cough center. EXPECTORANTS, also used in the treatment of cough, act locally.
Applications
UsesClobutinol Hydrochloride is a non-narcotic antitussive drug useful for treatment of acute respiratory diseases.
Upstream & downstream products
Upstream raw materials
Additional notes
DefinitionChEBI: Clobutinol hydrochloride is a member of benzenes and an organic amino compound.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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