5alpha-Androstan-3beta-ol

HCID 92877
NotesReactions
Substructure searchFind similar structures

Basic information

CAS
1224-92-6
Standard SMILES
C[C@@]12CCC[C@H]1[C@@H]1CC[C@H]3C[C@@H](O)CC[C@]3(C)[C@H]1CC2
InChIKey
DJTOLSNIKJIDFF-LOVVWNRFSA-N
Molecular formula
C19H32O
Average molar mass
276.5 g/mol
Monoisotopic mass
276.24531564

Overview

5alpha-Androstan-3beta-ol is a 3-hydroxy steroid. It has a role as an androgen.

Names & identifiers

Preferred name
5alpha-Androstan-3beta-ol
IUPAC
(3S,5S,8S,9S,10S,13S,14S)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
English name
5ALPHA-ANDROSTAN-3BETA-OL
Molecular formula
C19H32O
Molecular weight
276.46

Names & synonyms

5alpha-Androstan-3beta-ol1224-92-65a-androstan-3b-olAndrostanol5.alpha.-Androstan-3.beta.-ol3beta-Hydroxy-5alpha-androstane3.beta.-Hydroxy-5.alpha.-androstaneDTXSID4036514Androstan-3-ol, (3.beta.,5.alpha.)-CHEMBL198053(3S,5S,8S,9S,10S,13S,14S)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-olNSC-50887
Show more names
androstan-3-ol5α-Androstan-3β-olandrost-16-en-3β-ol5-A-androstan-3-B-ol5α(H)-Androstan-3β-ol5α-Androstan-3beta-ol5ALPHA-Androstan-3B-ol3β-Hydroxy-5α-androstaneandrost-16-en-3β-ol solution,100ppm
NCGC00181780-015|A-Androstan-3|A-ol(3S,5S,8S,9S,10S,13S,14S)-10,13-Dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-3-ol5alpha-Androstan-3beta-ol (1mg/ml in Acetonitrile)NSC 50887UNII-1394KPE67HEINECS 214-952-1Androstan-3-ol #

Database identifiers

CAS
1224-92-6
PubChem CID
92877
DTXSID
DTXSID4036514
ChEMBL
CHEMBL198053
ChEBI
CHEBI:177437
UNII
1394KPE67H
EC Number
214-952-1
Nikkaji
J80.100C

Properties

Computed structural properties

XLogP
5.9
Topological polar surface area
20.2 Ų
Hydrogen bond donors
1
Hydrogen bond acceptors
1
Rotatable bonds
0
Heavy atoms
20

Experimental & physicochemical properties

LipidsLipids -> Sterol Lipids [ST] -> Steroids [ST02] -> C19 steroids (androgens) and derivatives [ST0202]
Endocrine DisruptorsPotential endocrine disrupting compound
Physical DescriptionSolid

Physicochemical properties

Melting point
125 · 125-127°C
storage temp.
room temp
solubility
14 mg/mL · DMSO: 14 mg/mL at ≤60 °C, soluble
form
powder
color
White to Off-White
biological source
synthetic (organic)

Safety & regulation

GHS classification

GHS Classification · 4 items

Warning

H319 (97.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

P264+P265, P273, P280, P305+P351+P338, P337+P317, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Hazard Classes and CategoriesEye Irrit. 2 (97.4%)

Safety data

wgk
3
Signal word
Warning
Symbol(GHS)
GHS07
Hazard statements
H413
Precautionary statements
P273-P501

Chemistry & industry

Pharmacology

Cellular LocationsExtracellular

Applications

Uses5α-Androstan-3β-ol has been used as a cortisone analog to test its effect on the voltage-dependent potassium channel (Kv) current.

UsesAn Androstane metabolite.

Suppliers15 total

上海赛可锐生物科技有限公司021-58000709 13120558703 · [email protected]
上海维亦特生物科技有限公司15317051735 · [email protected]
凯试（上海）科技有限公司021-50135380 · [email protected]
Sigma-Aldrich西格玛奥德里奇(上海)贸易有限公司021-61415566 800-8193336 · [email protected]
天津阿尔塔科技有限公司022-6537-8550 15522853686 · [email protected]

Additional notes

DefinitionChEBI: 5alpha-Androstan-3beta-ol is a 3-hydroxy steroid. It has a role as an androgen.

Related reactions

1 records
New reaction record

Compound notes

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