6-Methyluridine
Basic information
- CAS
16710-13-7- Standard SMILES
Cc1cc(=O)[nH]c(=O)n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O- InChIKey
SGKGZYGMLGVQHP-ZOQUXTDFSA-N- Molecular formula
- C10H14N2O6
- Average molar mass
- 258.23 g/mol
- Monoisotopic mass
- 258.08518617
Names & identifiers
- Preferred name
- 6-Methyluridine
- IUPAC
- 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-methylpyrimidine-2,4-dione
- English name
- NSC 112513
- Molecular formula
- C10H14N2O6
- Molecular weight
- 258.23
Names & synonyms
6-Methyluridine16710-13-7RefChem:105069Uridine, 6-methyl-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-methylpyrimidine-2,4(1H,3H)-dione1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-methylpyrimidine-2,4-dione1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dioneNSC 112513SCHEMBL42101CHEMBL439055orb1908838SCHEMBL27763295
Show more names
6-Methyluridine For ribozymes
TNU0134AKOS027447341NM08576NSC 112513;DA-58907H634591-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-6-methyl-pyrimidine-2,4-dione
Database identifiers
- CAS
16710-13-7- PubChem CID
- 92887
- ChEMBL
CHEMBL439055- Nikkaji
- J1.295.258I
Properties
Computed structural properties
- XLogP
- -1.6
- Topological polar surface area
- 119 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 2
- Heavy atoms
- 18
- Formal charge
- 0
- Complexity
- 409
Physicochemical properties
- Density
- 1.576 · 1.576±0.06 g/cm3(Predicted)
- pka
- 9.42 · 9.42±0.40(Predicted)
Chemistry & industry
Applications
Uses6-Methyluridine exhibited weak antimalarial activity against P. falciparum 3D7 isolate. It is a weak substrate of Escherichia coli pyrimidine nucleoside phosphorylase.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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