Tetrahydro-2-hydroxyfuran (HCID 93002)

Names & identifiers

Preferred name: Tetrahydro-2-hydroxyfuran
IUPAC: oxolan-2-ol
English name: 2-ETHOXYTETRAHYDROFURAN
Molecular formula: C6H12O2
Molecular weight: 116.16

Names & synonyms

2-Hydroxytetrahydrofuran5371-52-8Tetrahydro-2-furanol2-Furanol, tetrahydro-Tetrahydro-2-hydroxyfuranV8YVV52DLWCHEBI:19662RefChem:87621236-569-9tetrahydrofuran-2-oloxolan-2-oltetrahydrofuryl alcohol

Show more names

2-ethoxyoxolaneEinecs 236-569-92-ETHOXYTETRAHYDROFURANFuran, 2-ethoxytetrahydro-2-Ethoxytetrahydrofuran 99%

MFCD073694572-hydroxy-tetrahydrofuran.alpha.-HydroxytetrahydrofuranDTXSID50968469AKOS006286535AS-57322SY016132CS-0197674

Database identifiers

CAS: 13436-46-9、5371-52-8
PubChem CID: 93002
DTXSID: DTXSID50968469
ChEBI: CHEBI:19662
UNII: V8YVV52DLW
EC Number: 236-569-9
Nikkaji: J131.583H

Properties

Computed structural properties

XLogP: 0
Topological polar surface area: 29.5 Å²
Hydrogen bond donors: 1
Hydrogen bond acceptors: 2
Rotatable bonds: 0
Heavy atoms: 6
Formal charge: 0
Complexity: 44

Physicochemical properties

Boiling point: 170 · 170-172 °C (lit.)
Density: 0.908 g/mL · 0.908 g/mL at 25 °C (lit.)
refractive index: 20 · n20/D 1.414(lit.)
Flash point: 61 °F · 61 °F
form: liquid
InChI: 1S/C6H12O2/c1-2-7-6-4-3-5-8-6/h6H,2-5H2,1H3
InChIKey: JQYYUWHWGCJWTN-UHFFFAOYSA-N
SMILES: CCOC1CCCO1
LogP: 0.13 · 0.130 (est)
UNSPSC Code: 12352100 · 12352100
Symbol(GHS): 2 · GHS02
Signal word: Danger
Hazard statements: 225 · H225
Precautionary statements: 210 · P210
PPE: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes: F
Risk Statements: 11 · 11
Safety Statements: 16 · 16-29-33
RIDADR: 1993 · UN 1993 3/PG 2
WGK Germany: 3 · 3
HazardClass: 3.1 · 3.1
PackingGroup: II
Storage Class: 3 · 3 - Flammable liquids
Hazard Classifications: 2 · Flam. Liq. 2

Safety & regulation

GHS classification

GHS Classification · 5 items

Danger

H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]

P210, P233, P240, P241, P242, P243, P280, P303+P361+P353, P370+P378, P403+P235, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 39 reports by companies from 1 notifications to the ECHA C&L Inventory.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Hazard information

Hazard Classes and CategoriesFlam. Liq. 2 (100%)

Safety data

PPE: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
wgk: 3
ridadr: UN 1993 3/PG 2
risk_code: 11
Signal word: Danger
Symbol(GHS): GHS02
hazard_code: F
safety_code: 16-29-33
hazard_class: 3.1
Storage Class: 3 - Flammable liquids
packing_group: II
Hazard statements: H225
Hazard Classifications: Flam. Liq. 2
Precautionary statements: P210

Chemistry & industry

Applications · 2 items

Uses2-Ethoxytetrahydrofuran was used to investigate quantitative, regioselective, O-acylative cleavage of tetrahydrofurans using organic acid halides in the presence of Bi(III) halides.

General Description2-Ethoxytetrahydrofuran undergoes Ln(OTf)3-catalyzed-Povarov coupling reaction with anilines and cyclopentadiene to yield tetrahydroquinolines. Transacetalization of 2-ethoxytetrahydrofuran with various alcohols catalyzed by Fe(ClO4)3 has been reported.