Tetrahydro-2-hydroxyfuran
Completing data — refresh the page later to see the latest
Basic information
- CAS
13436-46-9- Standard SMILES
OC1CCCO1- InChIKey
JNODDICFTDYODH-UHFFFAOYSA-N- Molecular formula
- C4H8O2
- Average molar mass
- 88.11 g/mol
- Monoisotopic mass
- 88.05242949
Overview
2-hydroxytetrahydrofuran is a monohydroxytetrahydrofuran.
Names & identifiers
- Preferred name
- Tetrahydro-2-hydroxyfuran
- IUPAC
- oxolan-2-ol
- English name
- 2-ETHOXYTETRAHYDROFURAN
- Molecular formula
- C6H12O2
- Molecular weight
- 116.16
Names & synonyms
2-Hydroxytetrahydrofuran5371-52-8Tetrahydro-2-furanol2-Furanol, tetrahydro-Tetrahydro-2-hydroxyfuranV8YVV52DLWCHEBI:19662RefChem:87621236-569-9tetrahydrofuran-2-oloxolan-2-oltetrahydrofuryl alcohol
Show more names
2-ethoxyoxolaneEinecs 236-569-92-ETHOXYTETRAHYDROFURANFuran, 2-ethoxytetrahydro-2-Ethoxytetrahydrofuran 99%
MFCD073694572-hydroxy-tetrahydrofuran.alpha.-HydroxytetrahydrofuranDTXSID50968469AKOS006286535AS-57322SY016132CS-0197674
Database identifiers
- CAS
13436-46-9、5371-52-8- PubChem CID
- 93002
- DTXSID
DTXSID50968469- ChEBI
CHEBI:19662- UNII
- V8YVV52DLW
- EC Number
- 236-569-9
- Nikkaji
- J131.583H
Properties
Computed structural propertiesFilling in
- XLogP
- 0
- Topological polar surface area
- 29.5 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 0
- Heavy atoms
- 6
- Formal charge
- 0
- Complexity
- 44.8
Physicochemical properties
- Boiling point
- 170 · 170-172 °C (lit.)
- Density
- 0.908 g/mL · 0.908 g/mL at 25 °C (lit.)
- refractive index
- 20 · n20/D 1.414(lit.)
- Flash point
- 61 °F · 61 °F
- form
- liquid
- InChI
- 1S/C6H12O2/c1-2-7-6-4-3-5-8-6/h6H,2-5H2,1H3
- InChIKey
- JQYYUWHWGCJWTN-UHFFFAOYSA-N
- SMILES
- CCOC1CCCO1
- LogP
- 0.13 · 0.130 (est)
- UNSPSC Code
- 12352100 · 12352100
- Symbol(GHS)
- 2 · GHS02
- Signal word
- Danger
- Hazard statements
- 225 · H225
- Precautionary statements
- 210 · P210
- PPE
- Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
- Hazard Codes
- F
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]
P210, P233, P240, P241, P242, P243, P280, P303+P361+P353, P370+P378, P403+P235, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 39 reports by companies from 1 notifications to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesFlam. Liq. 2 (100%)
Safety data
- PPE
- Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
- wgk
- 3
- ridadr
- UN 1993 3/PG 2
- risk_code
- 11
- Signal word
- Danger
- Symbol(GHS)
- GHS02
- hazard_code
- F
- safety_code
- 16-29-33
- hazard_class
- 3.1
- Storage Class
- 3 - Flammable liquids
- packing_group
- II
- Hazard statements
- H225
- Hazard Classifications
- Flam. Liq. 2
- Precautionary statements
- P210
Chemistry & industry
Applications
Uses2-Ethoxytetrahydrofuran was used to investigate quantitative, regioselective, O-acylative cleavage of tetrahydrofurans using organic acid halides in the presence of Bi(III) halides.
General Description2-Ethoxytetrahydrofuran undergoes Ln(OTf)3-catalyzed-Povarov coupling reaction with anilines and cyclopentadiene to yield tetrahydroquinolines. Transacetalization of 2-ethoxytetrahydrofuran with various alcohols catalyzed by Fe(ClO4)3 has been reported.
Upstream & downstream products
Upstream raw materials
Downstream products
Related reactions
14 records
Compound notes
Loading…