Basic information
- CAS
89112-85-6- Standard SMILES
COc1ccccc1-c1cc(=O)c2cc(C)ccc2o1- InChIKey
QEIHFNZSIRWEBX-UHFFFAOYSA-N- Molecular formula
- C17H14O3
- Average molar mass
- 266.29 g/mol
- Monoisotopic mass
- 266.0942943
Overview
sedative and anxiolytic; structure in first source
Names & identifiers
- Preferred name
- 2'-Methoxy-6-methylflavone
- IUPAC
- 2-(2-methoxyphenyl)-6-methylchromen-4-one
- English name
- 2-(2-Methoxyphenyl)-6-methyl-4H-1-benzopyran-4-one
- Molecular formula
- C17H14O3
- Molecular weight
- 266.29
Names & synonyms
2'MeO6MF2'-Methoxy-6-methylflavoneRefChem:90843689112-85-62-(2-methoxyphenyl)-6-methyl-4H-chromen-4-one2-(2-methoxyphenyl)-6-methylchromen-4-one4H-1-Benzopyran-4-one, 2-(2-methoxyphenyl)-6-methyl-2-(2-Methoxyphenyl)-6-methyl-4H-1-benzopyran-4-one6-Methyl-2'-methoxyflavoneCHEMBL334355F3139-0622orb1217523
Show more names
6-Methyl-2’-methoxyflavoneGamma-aminobutyric acid Receptor,2'MeO-6MF,α2β2/3γ2L,γ-Aminobutyric acid Receptor,inhibit,GABAA,inflammatory,2'MeO6MF,GABA Receptor,α2β1γ2L,Inhibitor,sedative,neuroprotection,anxiolytic,stroke,α2β2/3
orb1298549DTXSID40358996QEIHFNZSIRWEBX-UHFFFAOYSA-N2''MeO6MF, 10 mM in DMSOEX-A17530MFCD03691655STK788037AKOS002182005
Database identifiers
- CAS
89112-85-6- PubChem CID
- 930492
- DTXSID
Properties
Computed structural properties
- XLogP
- 3.5
- Topological polar surface area
- 35.5 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 2
- Heavy atoms
- 20
- Formal charge
- 0
- Complexity
- 401
Physicochemical properties
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 303 · H303-H315-H319-H335-H401
- Precautionary statements
- 261 · P261-P264-P271-P273-P280-P302+P352-P304+P340+P312-P305+P351+P338-P312-P332+P313-P337+P313-P403+P233-P405-P501
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H303-H315-H319-H335-H401
- Precautionary statements
- P261-P264-P271-P273-P280-P302+P352-P304+P340+P312-P305+P351+P338-P312-P332+P313-P337+P313-P403+P233-P405-P501
Chemistry & industry
Applications
Uses2'MeO6MF is a brain-penetrant positive allosteric modulator at α2β1γ2L and all α1-containing GABAA receptors. 2'MeO6MF also can directly activate α2β2/3 and α2β2/3γ2L GABAA receptors. 2'MeO6MF has anxiolytic and psychomotor stabilizing properties. 2'MeO6MF offers neuroprotection and improved functional recovery and dampens the stroke-induced inflammatory response[1][2].
Suppliers15 total
苏州景皓生物科技有限公司18136139868; 18136139868 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
江苏艾康生物医药研发有限公司025-66061636 19370895928 · [email protected]
北京博奥森生物技术有限公司400-901-9800 18611424007 · [email protected]
湖北魏氏化学试剂股份有限公司17771898297 13125137661 · [email protected]
上海敏寒医药科技有限公司17612188245 · [email protected]
金瓯生物医药（南京）有限公司13000000000 · [email protected]
普善实业（陕西）有限公司029-81310890 18165209495 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
BOC Sciences16314854226; +8616314854226 · [email protected]
上海超岚化工科技中心
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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