Lucifer Yellow carbohydrazide
Basic information
- CAS
67769-47-5- Standard SMILES
NNC(=O)NN1C(=O)c2cc(S(=O)(=O)[O-])cc3c(N)c(S(=O)(=O)[O-])cc(c23)C1=O.[Li+].[Li+]- InChIKey
RPKCZJYDUKVMGF-UHFFFAOYSA-L- Molecular formula
- C13H9Li2N5O9S2
- Average molar mass
- 457.3 g/mol
- Monoisotopic mass
- 457.0161761
Overview
Lucifer yellow carbohydrazide dye is an organic dilithium salt having 6-amino-2-[(hydrazinocarbonyl)amino]-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinoline-5,8-disulfonate as the counterion. It has a role as a fluorochrome. It contains a lucifer yellow carbohydrazide dye(2-).
Names & identifiers
- Preferred name
- Lucifer Yellow carbohydrazide
- IUPAC
- dilithium;6-amino-2-(hydrazinecarbonylamino)-1,3-dioxobenzo[de]isoquinoline-5,8-disulfonate
- English name
- LUCIFER YELLOW CH DILITHIUM SALT
- Molecular formula
- C13H12LiN5O9S2
- Molecular weight
- 453.33
Names & synonyms
Lucifer Yellow CHLucifer Yellow carbohydrazideMCO2N780C2DTXSID6040167NSC-3641661H-Benz(de)isoquinoline-5,8-disulfonic acid, 6-amino-2-((hydrazinocarbonyl)amino)-2,3-dihydro-1,3-dioxo-, dilithium saltRefChem:154235DTXCID4020167267-047-967769-47-5Lucifer Yellow CH dilithium saltLucifer Yellow CH (dilithium salt)
Show more names
LY-CHLUCIFER YELLOWLY CH Dilithium SaltLuc Yellow CH dilithiumLUCIFER YELLOW CH DILITHIUMLUCIFER YELLOW CH, LITHIUM SALT
UNII-MCO2N780C2EINECS 267-047-9dilithium;6-amino-2-(hydrazinecarbonylamino)-1,3-dioxobenzo[de]isoquinoline-5,8-disulfonateSCHEMBL94590orb1989203LUCIFER YELLOW CH [MI]lucifer yellow carbohydrazide dyeCHEBI:52106
Database identifiers
- CAS
Properties
Computed structural properties
- Topological polar surface area
- 262 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 11
- Rotatable bonds
- 0
- Heavy atoms
- 31
- Formal charge
- 0
- Complexity
- 914
Physicochemical properties
- Melting point
- 200 ℃ · >200 ℃
- storage temp.
- 2 · 2-8°C
- solubility
- 2 O: · H2O: soluble1mg/mL
- form
- Powder
- color
- Yellow to orange
- Appearance
- ocher powder
- Water Solubility
- 2 O: · H2O: 1mg/mL
- ex/em
- 431 · λex 431, 348, 280 nm; λem 542 nm in H2O
- λmax
- 280 nm, · 280nm, 428nm
- Merck
- 13 · 13,5616
- BRN
- 4644601 · 4644601
- Biological Applications
- Antiviral agents
- Major Application
- diagnostic assay manufacturinghematologyhistology
- InChIKey
- RPKCZJYDUKVMGF-UHFFFAOYSA-L
- SMILES
- [Li+].[Li+].NNC(=O)NN1C(=O)c2cc(cc3c(N)c(cc(C1=O)c23)S([O-])(=O)=O)S([O-])(=O)=O
- FDA UNII
- 2 N780C2 · MCO2N780C2
- UNSPSC Code
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- F
- 3-10-34
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 3
- safety_code
- 22-24/25
- Storage Class
- 11 - Combustible Solids
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Chemicals that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags.
Applications
DescriptionLucifer Yellow CH is a highly sensitive yellow fluorescent dye widely used in neurobiology, cytology, and molecular biology for cell tracing, studying cell-cell interactions, and visualizing neurons. The dye is suitable for labeling both live and fixed preparations: it has low cytotoxicity, is retained in cells after fixation (e.g., with paraformaldehyde), and is compatible with most immunochemistry protocols. Lucifer Yellow CH has a high quantum yield, is resistant to photobleaching, and is, therefore, ideal for confocal and fluorescence microscopy.The main dye application:Working dye concentration: 1–5% (depending on protocol).
UsesLucifer Yellow CH dilithium salt is a highly fluorescent dye. It can also be used as reactant/reagent in synthetic preparation of singlet oxygen-induced furan oxidation for site-specific and chemoselective peptide ligation. Dyes and metabolites.
UsesLucifer Yellow CH dilithium salt is a highly fluorescent dye, useful in marking nerve cells. It can be bound to tissue by conventional aldehyde-containing biological fixatives.
Additional notes
DefinitionChEBI: An organic dilithium salt having 6-amino-2-[(hydrazinocarbonyl)amino]-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinoline-5,8-disulfonate as the counterion.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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