Cor 32-24
Basic information
- CAS
91595-86-7- Standard SMILES
NC1=NCC(CN2CCN(c3ccccc3)CC2)O1- InChIKey
XSZLHACSCSAKOF-UHFFFAOYSA-N- Molecular formula
- C14H20N4O
- Average molar mass
- 260.33 g/mol
- Monoisotopic mass
- 260.16371127
Overview
structure given in first source
Names & identifiers
- Preferred name
- Cor 32-24
- IUPAC
- 5-[(4-phenylpiperazin-1-yl)methyl]-4,5-dihydro-1,3-oxazol-2-amine
- English name
- Cor 32-24
- Molecular weight
- 0
Names & synonyms
91595-86-7Cor 32-24COR-3224COR 32245-(1-phenyl-4-piperazino)methyl-2-amino-oxazolineRefChem:127935Pipoxazole4,5-Dihydro-5-(4-phenyl-1-piperazinylmethyl)-2-oxazolamine5-[(4-phenylpiperazin-1-yl)methyl]-4,5-dihydro-1,3-oxazol-2-amine4,5-dihydro-5-(methyl(4-phenyl-1-piperazinyl))-2-oxazolamine2-Oxazolamine, 4,5-dihydro-5-((4-phenyl-1-piperazinyl)methyl)-XSZLHACSCSAKOF-UHFFFAOYSA-N
Show more names
COR 3224. Pipoxazole5-(4-Phenylpiperazinomethyl)-2-oxazoline-2-amine5-[(1-Phenylpiperazin-4-yl)methyl]-2-amino-2-oxazoline1-[(2-Amino-4,5-dihydrooxazole-5-yl)methyl]-4-phenylpiperazine
2-Amino-5-(4-phenyl-1-piperazinylmethyl)-2-oxazolinecor3224orb1699625CHEMBL4741106SCHEMBL31175757DTXSID00919643COR-32-24AKOS040749213
Database identifiers
- CAS
91595-86-7- PubChem CID
- 93499
- DTXSID
DTXSID00919643- ChEMBL
CHEMBL4741106- Nikkaji
- J282.525B
Properties
Computed structural properties
- XLogP
- 0.9
- Topological polar surface area
- 54.1 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 3
- Heavy atoms
- 19
- Formal charge
- 0
- Complexity
- 319
Experimental & physicochemical properties
LogP0.85
Chemistry & industry
Applications
DescriptionPipoxazole, also known as COR-32-24 amd COR3224, is an adrenergic receptor antagonist potentially for the treatment of depression.
UsesCOR 32-24 is a compound that enters the brain through the purine transport system and has the activity of being transported by this system. The brain uptake index of COR 32-24 in rats decreases with the increase of the concentration of unlabeled compound, and its affinity for purine transporters is higher than that for adenine.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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