Basic information
- CAS
36675-91-9- Standard SMILES
O=c1[nH]c(=O)n([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)cc1O- InChIKey
QXDXBKZJFLRLCM-UAKXSSHOSA-N- Molecular formula
- C9H12N2O7
- Average molar mass
- 260.2 g/mol
- Monoisotopic mass
- 260.06445073
Overview
5-hydroxyuridine is a member of the class of uridines that is uridine in which the hydrogen at position 5 of the uracil ring is substituted by a hydroxy group. It is a member of uridines and an organic hydroxy compound.
Names & identifiers
- Preferred name
- 5-Hydroxyuridine
- IUPAC
- 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxypyrimidine-2,4-dione
- English name
- 5-HYDROXYURIDINE
- Molecular formula
- C9H12N2O7
- Molecular weight
- 260.2
Names & synonyms
5-Hydroxyuridine957-77-7isobarbituridineCHEBI:149645RefChem:102943213-487-1MFCD000105711-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-hydroxypyrimidine-2,4(1H,3H)-dioneUridine, 5-hydroxy-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxypyrimidine-2,4-dioneEINECS 213-487-1SCHEMBL451947
Show more names
5-Hydroxy-uridin5-Hydroxyuridine, isobarbituridine1-beta-D-Ribofuranosylisobarbituric acid1-(β-D-Ribofuranosyl)-5-hydroxypyrimidine-2,4(1H,3H)-dione5-Hydroxyuridine, isobarbituri dine,RNA-modified nucleoside ho5U, anticancer agent1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxy-pyrimidine-2,4-dione
DTXSID60914856C9H12N2O71-(beta-D-ribofuranosyl)-5-hydroxypyrimidine-2,4(1H,3H)-dioneF12676OHUrd1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-hydroxy-pyrimidine-2,4-dione5-Oxouridine5-?Hydroxyuridine
Properties
Computed structural properties
- XLogP
- -2.1
- Topological polar surface area
- 140 Ų
- Hydrogen bond donors
- 5
- Hydrogen bond acceptors
- 7
- Rotatable bonds
- 2
- Heavy atoms
- 18
- Formal charge
- 0
- Complexity
- 410
Physicochemical properties
- Melting point
- 240 °C · >240°C (dec.)
- Density
- 1.848 · 1.848±0.06 g/cm3(Predicted)
- storage temp.
- -20 °C · Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- Water (Slightly, Heated, Sonicated)
- form
- Solid
- pka
- 8 · 8+-.0.20(Predicted)
- color
- White to Off-White
- InChI
- InChI=1S/C9H12N2O7/c12-2-4-5(14)6(15)8(18-4)11-1-3(13)7(16)10-9(11)17/h1,4-6,8,12-15H,2H2,(H,10,16,17)/t4-,5-,6-,8-/m1/s1
- InChIKey
- QXDXBKZJFLRLCM-UAKXSSHOSA-N
- SMILES
- OC[C@H]1O[C@@H](N2C=C(O)C(=O)NC2=O)[C@H](O)[C@@H]1O
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319
- Precautionary statements
- 501 · P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H315-H319
- Precautionary statements
- P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330
Chemistry & industry
Applications
Uses5-Hydroxyuridine is a uridine (U829910), a nucleoside; widely distributed in nature. Uridine is one of the four basic components of ribonucleic acid (RNA).
Upstream & downstream products
Downstream products
Suppliers54 total
北京华美互利生物化工010-56205725 · [email protected]
广州佳途科技股份有限公司81960175-877 18933936954 · [email protected]
杭州品高化工有限公司0571-87658025 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
上海遐瑞医药科技有限公司+86-021-61551413 · [email protected]
T&W GROUP021-61551611 13296011611 · [email protected]
Aladdin Scientific[email protected]
宁波亿诺化学品有限公司86-574-27787657 · [email protected]
攀纳燊（河南）医药科学技术有限公司0371-65325800 13700860222 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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