Basic information
- CAS
27871-49-4- Standard SMILES
COC(=O)[C@H](C)O- InChIKey
LPEKGGXMPWTOCB-VKHMYHEASA-N- Molecular formula
- C4H8O3
- Average molar mass
- 104.1 g/mol
- Monoisotopic mass
- 104.04734411
Names & identifiers
- Preferred name
- methyl (S)-lactate
- IUPAC
- methyl (2S)-2-hydroxypropanoate
- English name
- Methyl (S)-(-)-lactate
- Molecular formula
- C4H8O3
- Molecular weight
- 104.1
Names & synonyms
27871-49-4Methyl (S)-(-)-lactateMethyl L-lactate(S)-Methyl lactate(-)-Methyl lactateMethyl (S)-2-hydroxypropionate(S)-Lactic acid methyl estermethyl (S)-lactateMethyl (S)-2-hydroxypropanoateMethyl lactate, L-Propanoic acid, 2-hydroxy-, methyl ester, (2S)-(-)-Lactic acid methyl ester
Show more names
L-Lactate(-)-METHYL L-LACTATE(-)-Methyl L-lactate(S)-Methyl 2-hydroxypropanoateMETHYL-(S)-LACTATEMETHYL L-(-)-LACTATE(2S)-2-Hydroxypropionic acid methyl ester
L-Methyl LactateL-lactic acid methyl ester(S)-(-)-methyl lactatemethyl (2S)-lactate(-)-2-Hydroxypropionic acid methyl esterLactic acid, methyl ester, L-L-lactate methyl esterEINECS 248-704-9
Database identifiers
- CAS
27871-49-4- PubChem CID
- 94386
- DTXSID
DTXSID9074359- ChEBI
CHEBI:83222- UNII
- 0379G9C44S
- EC Number
- 248-704-9
- Nikkaji
- J183.056B
Properties
Computed structural properties
- XLogP
- -0.1
- Topological polar surface area
- 46.5 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 2
- Heavy atoms
- 7
- Formal charge
- 0
- Complexity
- 69
Physicochemical properties
- Melting point
- -66 °C · -66°C
- alpha
- -8.5 · -8.5 º (neat)
- Boiling point
- 145 °C · 145 °C(lit.)
- Density
- 1.092 g/mL · 1.092 g/mL at 20 °C(lit.)
- refractive index
- 20 · n20/D 1.414
- FLAVIS Number
- 9.644 · 09.644 | (S)-Methyl lactate
- Flash point
- 121 °F · 121 °F
- storage temp.
- -20 °C · Sealed in dry,Store in freezer, under -20°C
- form
- Liquid
- pka
- 13.07 · 13.07±0.20(Predicted)
- color
- Clear
- optical activity
- 18 · [α]18/D 8.1°, neat
- explosive limit
- 2.2 % · 2.2%(V)
- Water Solubility
- miscible, hydrolyses
- Sensitive
- Moisture Sensitive
- BRN
- 1720587 · 1720587
- Cosmetics Ingredients Functions
- SOLVENTFLAVOURINGPERFUMING
- InChI
- 1S/C4H8O3/c1-3(5)4(6)7-2/h3,5H,1-2H3/t3-/m0/s1
- InChIKey
- LPEKGGXMPWTOCB-VKHMYHEASA-N
- SMILES
- COC(=O)[C@H](C)O
- LogP
- -0.549 · -0.549 (est)
- CAS DataBase Reference
- 27871 · 27871-49-4(CAS DataBase Reference)
- FDA UNII
- 379 G9C44S · 0379G9C44S
- EPA Substance Registry System
- 2 · Propanoic acid, 2-hydroxy-, methyl ester, (2S)- (27871-49-4)
- UNSPSC Code
- 12352108 · 12352108
- NACRES
- 22 · NA.22
- Symbol(GHS)
- 2 · GHS02,GHS07
- Signal word
- Warning
- Hazard statements
- 226 · H226-H319-H335
- Precautionary statements
- 210 · P210-P305+P351+P338
- target organs
- Respiratory system
- PPE
- Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
- Hazard Codes
- Xi
- Risk Statements
- 10 · 10-36/37
- Safety Statements
- 24 · 24
- RIDADR
- 3272 · UN 3272 3/PG 3
- WGK Germany
- 1 · 1
- F
- 21 · 21
- TSCA
- TSCA listed
- HazardClass
- 3 · 3
- PackingGroup
- III
- HS Code
- 29181100 · 29181100
- Storage Class
- 3 · 3 - Flammable liquids
- Hazard Classifications
- 2 Flam · Eye Irrit. 2Flam. Liq. 3STOT SE 3
- REACH Registrations
- Active
- Limited Quantities
- 5 L · 5.0 L (1.3 gallons) (liquid)
- Excepted Quantities
- Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
Safety & regulation
GHS classification
GHS Classification
Warning
H226: Flammable liquid and vapor [Warning Flammable liquids]；H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
P210, P233, P240, P241, P242, P243, P261, P264+P265, P271, P280, P303+P361+P353, P304+P340, P305+P351+P338, P319, P337+P317, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)
Warning
Hazard information
Regulatory Information
Chemical: Propanoic acid, 2-hydroxy-, methyl ester, (S)-
Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)
PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.
Status: Active Update: 30-03-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/5576
(S)-(-)-Methyl lactate: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and Categories
Flam. Liq. 3 (100%)；Eye Irrit. 2A (98.9%)；STOT SE 3 (100%)
Flammable liquid - category 3；Eye irritation - category 2；Specific target organ toxicity (single exposure) - category 3
Flam. Liq. 3；STOT SE 3；Eye Irrit. 2
Regulatory information
Regulatory Information
Chemical: Propanoic acid, 2-hydroxy-, methyl ester, (S)-
Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)
PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.
Status: Active Update: 30-03-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/5576
(S)-(-)-Methyl lactate: Does not have an individual approval but may be used under an appropriate group standard
Safety data
- F
- 21
- PPE
- Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
- wgk
- 1
- tsca
- TSCA listed
- ridadr
- UN 3272 3/PG 3
- hs_code
- 29181100
- risk_code
- 10-36/37
- Signal word
- Warning
- Symbol(GHS)
- GHS02,GHS07
- hazard_code
- Xi
- safety_code
- 24
- hazard_class
- 3
- Storage Class
- 3 - Flammable liquids
- packing_group
- III
- target organs
- Respiratory system
- Hazard statements
- H226-H319-H335
- Limited Quantities
- 5.0 L (1.3 gallons) (liquid)
- Excepted Quantities
- Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
- REACH Registrations
- Active
- Hazard Classifications
- Eye Irrit. 2Flam. Liq. 3STOT SE 3
- Precautionary statements
- P210-P305+P351+P338
Chemistry & industry
Uses & manufacturing
General Manufacturing InformationPropanoic acid, 2-hydroxy-, methyl ester, (2S)-: ACTIVE
Applications
UsesMethyl (S)-(-)-lactate is a methyl ester of L-Lactic acid.Methyl (S)-(-)-lactate is used in the synthesis of retinyl L-lactate by lipase-catalyzed transesterification .
UsesIt is used in pharmaceutical industry, agricultural fields and is also used as a solvent.
General DescriptionThis compound has benign qualities and is biodegradable, water miscible, and functions as a versatile solvent for CA membrane preparation. This is also used as an intermediate for the production of other chemicals, polymers, and derivatives. Thus this product has been enhanced for Safer solvents and auxiliaries.
Upstream & downstream products
Upstream raw materials
Downstream products
Suppliers100 total
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
衢州润东化工有限公司0570-8789886 18892685668 · [email protected]
Shandong chuangyingchemical Co., Ltd.18853181302 · [email protected]
温州共赢化学有限公司+86-0086-577-64498589 +86-15355981851 · [email protected]
河北创海生物科技有限公司+86-86-13131129325 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
韶远科技（上海）有限公司021-50795510 4000665055 · [email protected]
科瑞迪化学400-821-5857 021-64326257 · [email protected]
Syntechem Co.,Ltd[email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
北京华威锐科化工有限公司0757-86329057 18934348241 · [email protected]
阿法埃莎（中国）化学有限公司400-6106006 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
北京绿百草科技发展有限公司010-61136123 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
上海景颜化工科技有限公司13817811078 · [email protected]
嘉兴市艾森化工有限公司0573-85285100 18627885956 · [email protected]
上海隆盛化工有限公司58099637 13585536065 · [email protected]
孝感深远化工有限公司15527621225; 15527621225 · [email protected]
山东西亚化学有限公司13355009207 13355009207 · [email protected]
四川库利南科技有限公司400-1166-196 18981987031 · [email protected]
天津希恩思生化科技有限公司400 638 7771 · [email protected]
Xiamen AmoyChem Co., Ltd+86-86-5926051114 · [email protected]
南京化学试剂股份有限公司025-58369808 17895012682 · [email protected]
河南多贝化工有限公司0370-2785118 17550508557 · [email protected]
赛默飞世尔科技（中国）有限公司800-810-5118 · [email protected]
北京伊诺凯科技有限公司400-810-7969 010-59572699 · [email protected]
上海特伯化学科技有限公司+86-21-60341587 · [email protected]
上海健超生物科技有限公司150-2103-5486 18017383231 · [email protected]
TCI AMERICA800-4238616 · [email protected]
TOKYO CHEMICAL INDUSTRY CO., LTD.03-36680489 · [email protected]
TCI Europe320-37350700 · [email protected]
上海贤鼎生物科技有限公司4009209199 · [email protected]
上海将来实业股份有限公司021-61552785 · [email protected]
日照力德士化工有限公司010-51268198 · [email protected]
美岚实业（上海）有限公司021-58958189 · [email protected]
上海爱蝶实业有限公司021-58957966 18930537195 · [email protected]
广拓化学（上海）有限公司021-60899189-8001 18918189673 · [email protected]
上海馨远医药科技有限公司021-24206007 13764915196 · [email protected]
上海麦克林生化科技股份有限公司15221275939 15221275939 · [email protected]
杭州杰恒化工有限公司0571-87396432 · [email protected]
北京欣赛维化学科技有限公司010-56218822 13717722232 · [email protected]
江苏艾康生物医药研发有限公司025-66028182 17714375163 · [email protected]
上海凯赛化工有限公司021-33516722 13701817765 · [email protected]
北京华扬致成科技有限公司13716033033 · [email protected]
上海容立化学科技有限公司021-69992220 13701886816 · [email protected]
湖北巨胜科技有限公司027-59599241 18871490274 · [email protected]
池州凯隆进出口贸易有限公司[email protected]
Sigma-Aldrich西格玛奥德里奇(上海)贸易有限公司021-61415566 800-8193336 · [email protected]
Additional notes
DefinitionChEBI: A methyl 2-hydroxypropionate that has S configuration.
Related reactions
42 records
Compound notes
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