1-(2-Pyridyl)piperazine

HCID 94459
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Basic information

CAS
34803-66-2
Standard SMILES
c1ccc(N2CCNCC2)nc1
InChIKey
GZRKXKUVVPSREJ-UHFFFAOYSA-N
Molecular formula
C9H13N3
Average molar mass
163.22 g/mol
Monoisotopic mass
163.11094742

Overview

Stibavirin is a member of the class of cinnamic acids that is trans-cinnamic acid substituted by a dihydroxy(oxo)-5-stibanyl group at position 3 of the phenyl ring. It has a role as an anti-HIV-1 agent. It is a member of cinnamic acids and an antimony oxoacid.

Names & identifiers

Preferred name
1-(2-Pyridyl)piperazine
IUPAC
1-pyridin-2-ylpiperazine
English name
1-(2-Pyridyl)piperazine
Molecular formula
C9H13N3
Molecular weight
163.22

Names & synonyms

1-(2-Pyridyl)piperazine34803-66-21-(2-Pyridinyl)piperazine5IO1HZP7ZNNSC-137781DTXSID90188341NSC-26624RefChem:74210DTXCID20110832252-220-31-(pyridin-2-yl)piperazine1-Pyridin-2-yl-piperazine
Show more names
NSC13778NSC 26624NSC 137781AKOS BBS-00003613BUTTPARK 82\08-03RARECHEM AH CK 0193TIMTEC-BB SBB0064452-pyridyl piperazineLABOTEST-BB LTBB000605
1-pyridin-2-ylpiperazine2-PiperazinopyridinePiperazine, 1-(2-pyridinyl)-2-pyridylpiperazineMFCD000062162-(1-Piperazinyl)pyridine2-(Piperazin-1-yl)pyridineN-(2-pyridyl)piperazine

Database identifiers

CAS
34803-66-2
PubChem CID
94459
DTXSID
DTXSID90188341
ChEMBL
CHEMBL18094
ChEBI
CHEBI:231728
UNII
5IO1HZP7ZN
EC Number
252-220-3
Nikkaji
J208.913K

Properties

Computed structural properties

XLogP
0.7
Topological polar surface area
28.2 Ų
Hydrogen bond donors
1
Hydrogen bond acceptors
3
Rotatable bonds
1
Heavy atoms
12

Experimental & physicochemical properties

LogP0.74
Dissociation Constants8.9

Physicochemical properties

Melting point
92 · 92-94
Boiling point
120 · 120-122 °C/2 mmHg (lit.)
Density
1.072 g/mL · 1.072 g/mL at 25 °C (lit.)
refractive index
20 · n20/D 1.595(lit.)
Flash point
230 °F · >230 °F
storage temp.
Keep in dark place,Inert atmosphere,Room temperature

Safety & regulation

GHS classification

GHS Classification · 4 items

Danger

H314 (13.7%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P260, P261, P264, P264+P265, P271, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P319, P321, P332+P317, P337+P317, P362+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 51 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Hazard Classes and CategoriesSkin Corr. 1B (13.7%)

Safety data

F
10-34
PPE
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
wgk
3
ridadr
2735
hs_code
29339900
risk_code
36/37/38

Chemistry & industry

Applications · 3 items

Uses1-(2-Pyridyl)piperazine is a compound that belongs to a class of selective α2-adrenoceptor antagonists. 1-(2-Pyridyl)piperazine shows sympatholytic activity. 1-(2-Pyridyl)piperazine is also a metaboli te of Azaperone (A802200).

Uses1-(2-Pyridyl)piperazine was used to determine the aliphatic and aromatic isocyanates in air.

General Description1-(2-Pyridyl)piperazine is a piperazine derivative.

Upstream & downstream products

Suppliers100 total

国药集团化学试剂有限公司86-21-63210123 · [email protected]
常州帝通化工有限公司+86-0519-88298848 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
河北汤武科技有限公司15632360893 · [email protected]

Related reactions

407 records
New reaction record

Compound notes

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