Basic information
- CAS
26636-32-8- Standard SMILES
CCCCCCCCc1ccc(OCCO)cc1- InChIKey
BHNQPLPANNDEGL-UHFFFAOYSA-N- Molecular formula
- C16H26O2
- Average molar mass
- 250.38 g/mol
Overview
Nonidet P-40 is a poly(ether) macromolecule that is polyethylene glycol in which one of the terminal hydroxy groups has been converted to the corresponding p-octylphenyl ether. A nonionic, non-denaturing detergent, it is used for solubilising membrane proteins during isolation of membrane-protein complexes. n 8. It has a role as a detergent. It is a poly(ethylene glycol) derivative, an aromatic ether and a hydroxypolyether. It is functionally related to a 4-octylphenol.
Names & identifiers
- Preferred name
- Polyethylene glycol mono(octylphenyl) ether
- IUPAC
- 2-(4-octylphenoxy)ethanol
- English name
- POLYETHYLENE GLYCOL TERT-OCTYLPHENYL ETHER
- Molecular formula
- (C2H4O)nC14H22O
- Molecular weight
- 514.69
Names & synonyms
4-Octylphenol MonoethoxylateNonidet P40Octoxynol1Emulsifier OPSynperonic OPAlkasurf OPCharger EEthylan CPOctoxynol16Octoxynol20Octoxynol30Ethylan CPX
Show more names
OCTYLPHENOXYPOLYETHOXYETHANOLIGEPAL(R) CA-630NONIDET P40 SUBSTITUTEmono30DMT-SIOIGEPAL CA-210igepal ca-720Emulsifier 405TRITON(R) X-45
Alkasurf OP 5Alkasurf OP 8Cemulsol P 9Neutronyx 622Neutronyx 675Alkasurf OP 10Alkasurf OP 12Alkasurf OP 40
Database identifiers
- CAS
26636-32-8、51437-89-9、9036-19-5- PubChem CID
- 94543
- DTXSID
DTXSID20865310- ChEBI
CHEBI:78708- EC Number
- 257-203-4
- Nikkaji
- J261.723D
Properties
Computed structural properties
- XLogP
- 5
- Topological polar surface area
- 29.5 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 10
- Heavy atoms
- 18
- Formal charge
- 0
- Complexity
- 174
Experimental & physicochemical properties
PolymersOther Classes -> Polyoxyethylenes
Endocrine DisruptorsPotential endocrine disrupting compound
DecompositionWhen heated to decomposition it emits acrid smoke and fumes.
Physical DescriptionClear colorless or pale yellow liquid (n < 15); Hygroscopic (n >= 5); (n = avg # moles of ethylene oxide); [CHEMINFO] Clear pale yellow viscous liquid; [MSDSonline]
Physicochemical properties
- Melting point
- 48 · 48-50 °C(lit.)
- Density
- 1.1 g/mL · 1.10 g/mL at 20 °C
- refractive index
- 20 · n20/D 1.500
- Flash point
- 230 °F · >230 °F
- storage temp.
- 0 · 0-6°C
- Concentration
- 1 mCi/ml · 1 mCi/ml
- Solvent
- Sterile water
- Specific Activity
Safety & regulation
Hazard information
Hazards SummaryAn irritant; May cause serious eye injury; [MSDSonline]
FDA RequirementsOctylphenoxyethanols may be safely used as a component of articles intended for use in packaging, transporting, or holding food in accordance with prescribed conditions. /Octylphenoxyethanols/
Shipment Methods and Regulations
No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./
Safety & protection
Protective Action Criteria (PAC)
12 [mg/m3]
130 [mg/m3]
790 [mg/m3]
13 [mg/m3]
140 [mg/m3]
830 [mg/m3]
Regulatory information
FDA RequirementsOctylphenoxyethanols may be safely used as a component of articles intended for use in packaging, transporting, or holding food in accordance with prescribed conditions. /Octylphenoxyethanols/
Safety data
- F
- 3-8-10-23
- wgk
- 3
- rtecs
- YM0616666
- ridadr
- UN 3082 9/PG 3
- risk_code
- 41-36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07, GHS09
Chemistry & industry
Uses & manufacturing
Uses
Used as non-ionic detergent; [ChemIDplus] A nonionic surfactant polymer similar to octoxynol that has been used as a spermicide; [REPROTOX] Polyethylene glycol octylphenyl ether is a mixture of polymers with varying chain lengths. The polymeric content is generally greater than 98%. [CHEMINFO]
Household ProductsInformation on 74 consumer products that contain Octylphenoxypoly(ethoxyethanol) in the following categories is provided:
Applications
UsesPolyethylene glycol tert-octyl phenyl ether is formed by the polycondensation of octylphenol and ethylene oxide in the presence of an alkali catalyst. It is mainly used as liquid detergent, dye color improver or emulsifier in the textile industry.
Upstream & downstream products
Upstream raw materials
Suppliers9 total
艾吉析科技（上海）有限公司17717235263 · [email protected]
山东利腾生物科技有限公司+86-18663721413 +86-15552573001 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
凯试(上海)科技有限公司021-50135380 · [email protected]
南京佰瑞利康生物科技有限公司
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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