Basic information
- CAS
4546-70-7- Standard SMILES
Nc1nc(N)c2ncn([C@H]3C[C@H](O)[C@@H](CO)O3)c2n1- InChIKey
NOLHIMIFXOBLFF-KVQBGUIXSA-N- Molecular formula
- C10H14N6O3
- Average molar mass
- 266.26 g/mol
- Monoisotopic mass
- 266.11273833
Names & identifiers
- Preferred name
- 2-Amino-2'-deoxyadenosine
- IUPAC
- (2R,3S,5R)-5-(2,6-diaminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
- English name
- 2,6-Diaminopurine 2'-deoxyriboside
- Molecular formula
- C10H14N6O3
- Molecular weight
- 266.26
Names & synonyms
2-Amino-2'-deoxyadenosine4546-70-72,6-Diaminopurine-2'-deoxyribosideAdenosine, 2-amino-2'-deoxy-2,6-Diaminopurinedeoxyriboside4ZPH2F1JHRNSC 1043032,6-diaminopurine deoxyribosideUNII-4ZPH2F1JHR9H-Purine, 9-(2-deoxy-beta-D-erythro-pentofuranosyl)-2,6-diamino-NSC-1043032,6-DIAMINOPURINE-2'-DEOXYRIBOSIDE [USP IMPURITY]
Show more names
9-(2-Deoxy-β-D-erythro-pentofuranosyl)-9H-purin-2,6-diamineCladribine EP Impurity A(2R,3S,5R)-5-(2,6-diamino-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-olNsc1043032-NH2-2'-dAKraqubin impurity 12.6 2’-Deoxyguanosine2-NH2-2'-deoxyadenosine2-NH2-2"-deaxyadenosine
2,6-DIAMINO-9-(2'-DEOXY-.BETA.-D-RIBOFURANOSYL)PURINECLADRIBINE IMPURITY A [EP IMPURITY]2,6-DIAMINO-9-(2-DEOXY-.BETA.-D-ERYTHRO-PENTOFURANOSYL)PURINE9H-PURINE, 2,6-DIAMINO-9-(2-DEOXY-.BETA.-D-ERYTHRO-PENTOFURANOSYL)-CLADRIBINE IMPURITY A (EP IMPURITY)2,6-DIAMINOPURINE-2'-DEOXYRIBOSIDE (USP IMPURITY)RefChem:1976622,6-DIAMINO-9-(2'-DEOXY-BETA-D-RIBOFURANOSYL)PURINE
Properties
Computed structural properties
- XLogP
- -0.5
- Topological polar surface area
- 145 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 8
- Rotatable bonds
- 2
- Heavy atoms
- 19
- Formal charge
- 0
- Complexity
- 334
Experimental & physicochemical properties
LogP-0.52
Physicochemical properties
- Melting point
- 144 °C · 144°C
- Boiling point
- 748.4 · 748.4±70.0 °C(Predicted)
- Density
- 2.08 · 2.08±0.1 g/cm3(Predicted)
- storage temp.
- 2 · Keep in dark place,Inert atmosphere,2-8°C
- solubility
- DMSO (Slightly, Heated), Methanol (slightly, Heated), Water (Slightly, Sonicated)
- pka
- 13.79 · 13.79±0.60(Predicted)
- form
- Powder
- color
- White to Off-white
- Major Application
- pharmaceutical small molecule
- InChI
- InChI=1S/C10H14N6O3/c11-8-7-9(15-10(12)14-8)16(3-13-7)6-1-4(18)5(2-17)19-6/h3-6,17-18H,1-2H2,(H4,11,12,14,15)/t4-,5+,6+/m0/s1
- InChIKey
- NOLHIMIFXOBLFF-KVQBGUIXSA-N
- SMILES
- OC[C@H]1O[C@@H](N2C3C(=C(N=C(N)N=3)N)N=C2)C[C@@H]1O
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- wgk
- 3
- rtecs
- UO7523300
- hs_code
- 29389090
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
Chemistry & industry
Applications
Uses2,6-Diaminopurine-2’-deoxyriboside is a nucleoside analogs synthesized to interfere with DNA metabolism. A derivative of 2,6-Diaminopurine (D416580), which can be used as analyte for biological and analytical studies of incorporation of unnatural nucleotides into mutant tRNA and proteins.
Suppliers100 total
山东玖玥生物科技有限公司15553333686 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
湖北永阔科技有限公司027-59223108 15972152991 · [email protected]
南通飞宇生物科技有限公司0513-68819626 15152877458 · [email protected]
上海康朗生物科技有限公司021-61998208 18217752821 · [email protected]
武汉敬康恩生物医药科技有限公司13720134139 086-15871494362 13720134139 · [email protected]
艾吉析科技（上海）有限公司17717235263 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
广州隽沐生物科技股份有限公司020-36607679; 13502246435 · [email protected]
广州佳途科技股份有限公司81960175-877 18933936954 · [email protected]
河南闰霖化工有限公司+86-18738066252; +86-18738066252 · [email protected]
Related reactions
3 records
Compound notes
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