Basic information
- CAS
13794-65-5- Standard SMILES
Nc1nc(N)c2cc(NCc3ccc(Cl)c(Cl)c3)ccc2n1- InChIKey
LTSQDQVTNREIAO-UHFFFAOYSA-N- Molecular formula
- C15H13Cl2N5
- Average molar mass
- 334.2 g/mol
- Monoisotopic mass
- 333.0548008
Names & identifiers
- Preferred name
- Pam 1392
- IUPAC
- 6-N-[(3,4-dichlorophenyl)methyl]quinazoline-2,4,6-triamine
- English name
- 2,4,6-Quinazolinetriamine, N6-[(3,4-dichlorophenyl)methyl]-
- Molecular formula
- C15H13Cl2N5
- Molecular weight
- 334.2
Names & synonyms
Pam 139213794-65-5Pam-1392NSC-1297895G7XW6J5HWDTXSID501604062,4,6-Quinazolinetriamine, N6-((3,4-dichlorophenyl)methyl)-N6-((3,4-Dichlorophenyl)methyl)-2,4,6-quinazolinetriamineN6-[(3,4-Dichlorophenyl)methyl]-2,4,6-quinazolinetriamine2,4,6-Quinazolinetriamine, N6-[(3,4-dichlorophenyl)methyl]-RefChem:169805DTXCID7082897
Show more names
AI352841AI3 52841N(6)-(3,4-dichlorobenzyl)-2,4,6-quinazolinetriamine
2,4-Diamino-6-(3,4-dichlorobenzylamino)quinazolineCHEMBL4140176-N-[(3,4-dichlorophenyl)methyl]quinazoline-2,4,6-triamineNSC 129789AI3-52841orb1695760BDBM50404676N6-[(3,4-DICHLOROPHENYL)METHYL]QUINAZOLINE-2,4,6-TRIAMINE
Database identifiers
- CAS
13794-65-5- PubChem CID
- 97523
- DTXSID
DTXSID50160406- ChEMBL
CHEMBL414017- UNII
- 5G7XW6J5HW
Properties
Computed structural properties
- XLogP
- 3.6
- Topological polar surface area
- 89.9 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 3
- Heavy atoms
- 22
- Formal charge
- 0
- Complexity
- 372
Experimental & physicochemical properties
LogP2.53
Chemistry & industry
Applications
DescriptionPam 1392 is a chemotherapeutic agent.
UsesPAM 1392 is active orally against Plasmodium berghei in mice, P. cynofologi and P. knowlesi in monkeys and Trypanosoma cruzi in tissue cultures of mice, and hemolytic streptococci in vitro. PAM 1392 has antimalarial and antitrypanosomal activities, which is proming for rasearch of drug-resistant malaria[1][2].
Suppliers3 total
上海陶术生物科技股份有限公司13564774135 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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