Basic information
- CAS
23740-25-2- Standard SMILES
COc1ccc2c(c1)C(=O)c1nccc3cc4c(c-2c13)OCO4- InChIKey
WLXLLQQGGGHOMA-UHFFFAOYSA-N- Molecular formula
- C18H11NO4
- Average molar mass
- 305.3 g/mol
- Monoisotopic mass
- 305.06880783
Overview
lanuginosine has been reported in Magnolia compressa, Fissistigma oldhamii, and other organisms with data available.
Names & identifiers
- Preferred name
- Lanuginosine
- IUPAC
- 16-methoxy-3,5-dioxa-11-azapentacyclo[10.7.1.02,6.08,20.014,19]icosa-1(20),2(6),7,9,11,14(19),15,17-octaen-13-one
- English name
- 9-Methoxy-1,2-methylenedioxy-7-oxaporphine
- Molecular formula
- C18H11NO4
- Molecular weight
- 305.28
Names & synonyms
LanuginosineOxoxylopine23740-25-2OxoxylopinL7DSM4NF0PCCRIS 3814UNII-L7DSM4NF0PNSC 137553NSC-137553BRN 06241238H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinolin-8-one, 10-methoxy-Noraporphin-7-one, 4,5,6,6a-tetradehydro-9-methoxy-1,2-(methylenedioxy)-
Show more names
NSC1375539-Methoxy-1,2-methylenedioxy-7-oxaporphine10-Methoxy-8H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinolin-8-one8H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinolin-8-one, 10-methoxy-
16-methoxy-3,5-dioxa-11-azapentacyclo[10.7.1.02,6.08,20.014,19]icosa-1(20),2(6),7,9,11,14(19),15,17-octaen-13-one16-methoxy-3,5-dioxa-11-azapentacyclo(10.7.1.02,6.08,20.014,19)icosa-1(20),2(6),7,9,11,14(19),15,17-octaen-13-oneRefChem:1523408H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinolin-8-one, 10-methoxy-(9CI)CHEMBL389400orb1696614SCHEMBL6687528SCHEMBL30723114
Database identifiers
- CAS
23740-25-2- PubChem CID
Properties
Computed structural properties
- XLogP
- 3.4
- Topological polar surface area
- 57.7 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 1
- Heavy atoms
- 23
- Formal charge
- 0
- Complexity
- 497
Physicochemical properties
- Melting point
- 302 · 302-3°C (dec.).
- form
- Solid
- color
- Yellow to brown
- FDA UNII
- 7 DSM4NF0P · L7DSM4NF0P
Chemistry & industry
Applications
DescriptionAn oxoaporphine alkaloid which has been isolated from the eHCl3 extract of the trunk bark of Michelia lanuginosa Wall., the structure has been established from the ultraviolet, infrared, NMR and mass spectra. All attempts to reduce the alka_x0002_loid, either with NaBH4 or catalytic hydrogenation with Pt02, have failed due to the ready oxidation of the reduction product in solution.
UsesLanuginosine (Compound 12) is an AChE inhibitor (IC50: 10.9 μM). Lanuginosine inhibits Aβ aggregation. Lanuginosine can be used for research of Alzheimer’s disease[1].
Suppliers4 total
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
上海梅凯科技有限公司021-68689288 15300790979 · [email protected]
山东钥熠材料科技有限公司18173438764 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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