(2S,4S)-4-(tert-butoxy)-1-[(9H-fluoren-9-ylmethoxy)carbonyl]pyrrolidine-2-carboxylic acid
Basic information
- CAS
464193-92-8- Standard SMILES
CC(C)(C)O[C@H]1C[C@@H](C(=O)O)N(C(=O)OCC2c3ccccc3-c3ccccc32)C1- InChIKey
WPBXBYOKQUEIDW-BTYIYWSLSA-N- Molecular formula
- C24H27NO5
- Average molar mass
- 409.5 g/mol
- Monoisotopic mass
- 409.18892296
Names & identifiers
- Preferred name
- (2S,4S)-4-(tert-butoxy)-1-[(9H-fluoren-9-ylmethoxy)carbonyl]pyrrolidine-2-carboxylic acid
- IUPAC
- (2S,4S)-1-(9H-fluoren-9-ylmethoxycarbonyl)-4-[(2-methylpropan-2-yl)oxy]pyrrolidine-2-carboxylic acid
- English name
- Fmoc-D-Hyp(tBu)-OH
- Molecular formula
- C24H27NO5
- Molecular weight
- 409.48
Names & synonyms
464193-92-8Fmoc-D-Hyp(tBu)-OHFmoc-cis-Hyp(tBu)-OH(2S,4S)-4-(tert-butoxy)-1-[(9H-fluoren-9-ylmethoxy)carbonyl]pyrrolidine-2-carboxylic acidfmoc-cis-4-tert-butoxy-l-proline(2S,4S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-(tert-butoxy)pyrrolidine-2-carboxylic acidMFCD22415192(2S,4S)-4-tert-butoxy-1-(9H-fluoren-9-ylmethoxycarbonyl)pyrrolidine-2-carboxylic acid(2S,4S)-1-(9H-fluoren-9-ylmethoxycarbonyl)-4-[(2-methylpropan-2-yl)oxy]pyrrolidine-2-carboxylic acidfmoc-cis-4-t-butoxy-l-prolineSCHEMBL8131557AKOS025146821
Show more names
Fmoc-cis-L-hyp(tbu)-ohFMOC-D-HYP(TBU)-OH USP/EP/BPFMOC-D-HYDROXYPROLINE(TBU)-OHFMOC-O-T-BUTYL-D-4-HYDROXYPROLINEN-Fmoc-(4S)-4-tert-butoxy-L-prolineFmoc-O-tert-butyl-D-4-hydroxyprolineFMOC-O-T-BUTYL-D-TRANS-4-HYDROXYPROLINEFmoc-trans-4-hydroxy-D-proline tert-butyl ester
AS-34117SY098540CS-0053412P15686F548267(2S,4S)-4-(tert-Butoxy)-1-Fmoc-pyrrolidine-2-carboxylic Acid(2S,4S)-4-(1,1-Dimethylethoxy)-1-(9H-fluoren-9-ylmethyl)-1,2-pyrrolidinedicarboxylic acid ester
Properties
Computed structural properties
- XLogP
- 3.9
- Topological polar surface area
- 76.1 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 6
- Heavy atoms
- 30
- Formal charge
- 0
- Complexity
- 622
Physicochemical properties
- Boiling point
- 578.6 · 578.6±50.0 °C(Predicted)
- Density
- 1.28 · 1.28±0.1 g/cm3(Predicted)
- storage temp.
- 2 · Sealed in dry,2-8°C
- pka
- 3.71 · 3.71±0.40(Predicted)
- Appearance
- White to off-white Solid
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 317 · H317-H319
- Precautionary statements
- 280 · P280-P305+P351+P338
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H317-H319
- Precautionary statements
- P280-P305+P351+P338
Chemistry & industry
Applications
UsesFmoc-D-Hyp(tBu)-OH is a key intermediate in the synthesis of new collagen model peptides containing 4-hydroxyproline and 4-fluoroproline.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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