Basic information
- CAS
122996-47-8- Standard SMILES
CC(C)(C)O[C@@H]1C[C@@H](C(=O)O)N(C(=O)OCC2c3ccccc3-c3ccccc32)C1- InChIKey
WPBXBYOKQUEIDW-VFNWGFHPSA-N- Molecular formula
- C24H27NO5
- Average molar mass
- 409.5 g/mol
- Monoisotopic mass
- 409.18892296
Names & identifiers
- Preferred name
- (2S,4R)-4-(tert-butoxy)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}pyrrolidine-2-carboxylic acid
- IUPAC
- (2S,4R)-1-(9H-fluoren-9-ylmethoxycarbonyl)-4-[(2-methylpropan-2-yl)oxy]pyrrolidine-2-carboxylic acid
- English name
- Fmoc-Hyp(tBu)-OH
- Molecular formula
- C24H27NO5
- Molecular weight
- 409.48
Names & synonyms
(2S,4R)-4-(tert-butoxy)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}pyrrolidine-2-carboxylic acid(2S,4R)-4-(tert-butoxy)-1-(((9H-fluoren-9-yl)methoxy)carbonyl)pyrrolidine-2-carboxylic acidRefChem:398939857-376-1Fmoc-Hyp(tBu)-OH122996-47-8fmoc-4-tert-butoxy-l-prolineFmoc-L-Hyp(tBu)-OHMFCD00151930(2S,4R)-1-(9H-fluoren-9-ylmethoxycarbonyl)-4-[(2-methylpropan-2-yl)oxy]pyrrolidine-2-carboxylic acidSCHEMBL118220Fmoc-O-tert-butyl-L-trans-4-hydroxyproline
Show more names
Fmoc-Hyp(OtBu)-OHFmoc-Hyp(tBu)FMOC-HYP(BUT)-OHtrans-N-Fmoc-4-tert-butoxy-L-proline(2S)-1-(((9H-FLUOREN-9-YL)METHOXY)CARBONYL)-4-(TERT-BUTOXY)PYRROLIDINE-2-CARBOXYLIC ACIDFmoc-Hyp(tBu)-OH 97%
(2S,4R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-(tert-butoxy)pyrrolidine-2-carboxylic acidFmoc-O-tert-butyl-L-hydroxyprolineTrans-N-Fmoc-4-(tert-butoxy)-L-prolineFmoc-D-Hyp(tBu)-OHN-alpha-Fmoc-O-tert-butyl-L-trans-4-hydroxyprolineN-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-trans-(tert-butoxy)-L-prolineFmoc-(2S,4R)-(-)-4-t-butoxypyrrolidine-2-carboxylic acid1,2-Pyrrolidinedicarboxylic acid, 4-(1,1-dimethylethoxy)-, 1-(9H-fluoren-9-ylmethyl) ester, (2S,4R)-
Properties
Computed structural properties
- XLogP
- 3.9
- Topological polar surface area
- 76.1 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 6
- Heavy atoms
- 30
- Formal charge
- 0
- Complexity
- 622
Physicochemical properties
- Melting point
- 63 °C · ~63 °C
- Boiling point
- 578.6 · 578.6±50.0 °C(Predicted)
- Density
- 1.28 · 1.28±0.1 g/cm3(Predicted)
- storage temp.
- 2 · 2-8°C
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- pka
- 3.71 · 3.71±0.40(Predicted)
- color
- White
- optical activity
- 20 · [α]20/D 25±2.5°, c = 1% in methanol
- BRN
- 6161467 · 6161467
- Major Application
- peptide synthesis
- InChIKey
- WPBXBYOKQUEIDW-VFNWGFHPSA-N
- SMILES
- N1(C(OCC2C3=C(C=CC=C3)C3=C2C=CC=C3)=O)C[C@H](OC(C)(C)C)C[C@H]1C(O)=O
- CAS DataBase Reference
- 122996 · 122996-47-8(CAS DataBase Reference)
- UNSPSC Code
- 12352209 · 12352209
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Safety data
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 3
- hs_code
- 2933 99 80
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- safety_code
- 22-24/25
- hazard_class
- IRRITANT
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P271-P261
Chemistry & industry
Applications
UsesFmoc-Hyp(tBu)-OH, is an amino acid derivative, used in chemical synthesis and peptide chemistry.
Suppliers100 total
北京华美互利生物化工010-56205725 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
江苏吉泰肽业科技有限公司18936337900 18936337900 · [email protected]
上海策嵘生物科技有限公司[email protected]
温州共赢化学有限公司+86-0086-577-64498589 +86-15355981851 · [email protected]
Hangzhou Go Top Peptide Biotech0571-88211921 · [email protected]
上海嘉莱多生物技术有限责任公司021-61732478 19946252459 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
韶远科技（上海）有限公司4000665055 · [email protected]
Ark Pharm, Inc.847-367-3680 · [email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
北京华威锐科化工有限公司0757-86329057 18934348241 · [email protected]
Related reactions
1 records
Compound notes
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