NVP-DPP-728 dihydrochloride
Basic information
- CAS
207556-62-5- Standard SMILES
Cl.Cl.N#Cc1ccc(NCCNCC(=O)N2CCC[C@H]2C#N)nc1- InChIKey
VNACOBVZDCLAEV-GXKRWWSZSA-N- Molecular formula
- C15H20Cl2N6O
- Average molar mass
- 371.3 g/mol
- Monoisotopic mass
- 370.1075647
Names & identifiers
- Preferred name
- NVP-DPP-728 dihydrochloride
- IUPAC
- 6-[2-[[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]amino]ethylamino]pyridine-3-carbonitrile;dihydrochloride
- English name
- DPP 728
- Molecular formula
- C15H20Cl2N6O
- Molecular weight
- 371.2649
Names & synonyms
207556-62-5PWKTKAMJURNVP-DPP-728 dihydrochloridedpp-728UNII-PWKTKAMJUR1-(2-((5-Cyano-2-pyridinyl)amino)ethylamino)acetyl-2-pyrrolidinecarbonitrile dihydrochloride, (2S)-2-Pyrrolidinecarbonitrile, 1-(((2-((5-cyano-2-pyridinyl)amino)ethyl)amino)acetyl)-, dihydrochloride, (2S)-RefChem:202335NVP DPP 728 DIHYDROCHLORIDENVP-DPP728 dihydrochlorideNVP-DPP728 (dihydrochloride)(S)-6-((2-((2-(2-cyanopyrrolidin-1-yl)-2-oxoethyl)amino)ethyl)amino)nicotinonitrile dihydrochloride
Show more names
6-[2-[[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]amino]ethylamino]pyridine-3-carbonitrile:dihydrochloride
NVP-DPP 728DPP 728NVP 728SCHEMBL356225orb1691277EX-A10428AAKOS0244576486-[2-[[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]amino]ethylamino]pyridine-3-carbonitrile;dihydrochloride
Database identifiers
- CAS
207556-62-5- PubChem CID
- 9799555
- UNII
- PWKTKAMJUR
Properties
Computed structural properties
- Topological polar surface area
- 105 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 6
- Heavy atoms
- 24
- Formal charge
- 0
- Complexity
- 475
Physicochemical properties
- FDA UNII
- PWKTKAMJUR
Chemistry & industry
Applications
UsesNVP DPP 728 Dihydrochloride is a new potent DPP-IV inhibitor class with excellent oral bioavailability and potent antihyperglycemic activity.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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