Basic information
- CAS
342026-92-0- Standard SMILES
CCOc1nn(Cc2ccc(OCc3csc(-c4ccccc4)n3)cc2)cc1CCC(=O)O- InChIKey
SRFCAWATPLCLMG-UHFFFAOYSA-N- Molecular formula
- C25H25N3O4S
- Average molar mass
- 463.6 g/mol
- Monoisotopic mass
- 463.15657746
Names & identifiers
- Preferred name
- Sipoglitazar
- IUPAC
- 3-[3-ethoxy-1-[[4-[(2-phenyl-1,3-thiazol-4-yl)methoxy]phenyl]methyl]pyrazol-4-yl]propanoic acid
- English name
- Sipoglitazar
- Molecular formula
- C25H25N3O4S
- Molecular weight
- 463.5487
Names & synonyms
Sipoglitazar342026-92-040O898CJZBTAK-6543-(3-Ethoxy-1-(4-((2-phenyl-1,3-thiazol-4-yl)methoxy)benzyl)-1H-pyrazol-4-yl)propanoic acidDTXSID508703313-[3-ethoxy-1-[[4-[(2-phenyl-1,3-thiazol-4-yl)methoxy]phenyl]methyl]pyrazol-4-yl]propanoic Acid3-(3-ethoxy-1-((4-((2-phenyl-1,3-thiazol-4-yl)methoxy)phenyl)methyl)pyrazol-4-yl)propanoic acidsipoglitazarum3-(3-Ethoxy-1-{4-[(2-phenyl-1,3-thiazol-4-yl)methoxy]benzyl}-1H-pyrazol-4-yl)propanoic acidRefChem:183229DTXCID50818076
Show more names
TAK654TAK 654CS-15683-[3-Ethoxy-1-[4-(2-phenyl-4-thiazolylMethoxy)benzyl]-1H-pyrazol-4-yl]propionic Acid3-[3-Ethoxy-1-[4-[(2-phenyl-1,3-thiazol-4-yl)Methoxy]benzyl]-1H-pyrazol-4-yl]propionic Acid1H-Pyrazole-4-propanoic acid, 3-ethoxy-1-[[4-[(2-phenyl-4-thiazolyl)methoxy]phenyl]methyl]-
Sipoglitazar [INN]UNII-40O898CJZB3-Ethoxy-1-[[4-[(2-phenyl-4-thiazolyl)methoxy]phenyl]methyl]-1H-pyrazole-4-propanoic acid3-[3-ethoxy-1-({4-[(2-phenyl-1,3-thiazol-4-yl)methoxy]phenyl}methyl)-1H-pyrazol-4-yl]propanoic acidorb1699299SCHEMBL5380746CHEMBL3526439SRFCAWATPLCLMG-UHFFFAOYSA-N
Database identifiers
- CAS
342026-92-0- PubChem CID
- 9825652
- DTXSID
DTXSID50870331- ChEMBL
CHEMBL3526439- UNII
- 40O898CJZB
- Nikkaji
- J3.083.755J
Properties
Computed structural properties
- XLogP
- 4.5
- Topological polar surface area
- 115 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 7
- Rotatable bonds
- 11
- Heavy atoms
- 33
- Formal charge
- 0
- Complexity
- 598
Physicochemical properties
- Melting point
- 111 · 111-112oC
- storage temp.
- -20 °C · -20°C Freezer
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White
- FDA UNII
- 40 O898CJZB · 40O898CJZB
Chemistry & industry
Applications
UsesSipoglitazar is a novel antidiabetic agent. Sipoglitazar displays triple agonistic activities on the human peroxisome proliferator-activated receptors, hPPAR-γ, -α, and -δ.
Suppliers27 total
江苏艾康生物医药研发有限公司025-58851090 19370895928 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
凯试(上海)科技有限公司021-50135380 · [email protected]
武汉丰泰威远科技有限公司+86-27-8746-5837 +86-18627785180 · [email protected]
武汉丰泰威远科技有限公司027-87465837 19945049750 · [email protected]
杭州宇昊化工科技有限公司0571-82693216 · [email protected]
上海楼岚生物科技有限公司021-52996696，15000506266 15000506266
苏州克瑞斯特医药科技有限公司0512-62910395 17751098781 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
HANGZHOU LEAP CHEM CO., LTD.+86-571-87711850 +86-15355479329 · [email protected]
上海德轩医药科技有限公司[email protected] · [email protected]
苏州美石生物科技有限公司1173954148q · [email protected]
艾吉析科技（上海）有限公司17721401538;17717235263 17721401538 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
安泰精细化工技术有限公司18503026267 · [email protected]
Cckinase, Inc.+1 (732)236-3202 · [email protected]
成都诺维尔生物医药有限公司028-85255396 18302801538 · [email protected]
Suzhou Laing Biotechnology Co.,Ltd+86-13004516015 +86-18149392822 · [email protected]
爱必信（上海）生物科技有限公司13761418683 · [email protected]
深圳聚合生化科技有限公司+86-400-002-6226 · [email protected]
苏州诺行贸易有限公司0512-65816829 18662214788 · [email protected]
郑州汇聚化工有限公司037155153829 18003835034 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
ChemeGen 中国18818260767 · [email protected]
上海相辉医药科技有限公司13611835272 13611835272 · [email protected]
北京百灵威科技有限公司18210857532 18210857532 · [email protected]
上海弘渠生物医药科技有限公司88888888888 · [email protected]
Related reactions
1 records
Compound notes
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