Basic information
- CAS
406-90-6- Standard SMILES
C=COCC(F)(F)F- InChIKey
DLEGDLSLRSOURQ-UHFFFAOYSA-N- Molecular formula
- CF3CH2OCH=CH2
- Average molar mass
- 126.08 g/mol
- Monoisotopic mass
- 126.02924926
Overview
Volatile Liquid. Bp: 43 °C. Density: 1.14 g cm-3. Formerly used as an inhalation anesthetic.
Names & identifiers
- Preferred name
- Fluroxene
- IUPAC
- 2-ethenoxy-1,1,1-trifluoroethane
- English name
- 2,2,2-Trifluoroethyl vinyl ether
- Molecular formula
- C4H5F3O
- Molecular weight
- 126.08
Names & synonyms
FLUROXENE406-90-62,2,2-Trifluoroethyl vinyl etherFluoromarEthene, (2,2,2-trifluoroethoxy)-FlurosseneFO7JHA3G03NSC-760364fluoroxene2,2,2-TrifluoroethoxyetheneRefChem:599468206-977-1
Show more names
Fluroxenfluorxenefloroxenefluooxenetrifluoroethylvinylether2,2,2-trifluoroethoxyethylene
(2,2,2-Trifluoroethoxy)ethene2-ethenoxy-1,1,1-trifluoroethaneFluroxenoMFCD00864407Fluroxene (USAN)FLUROXENE [USAN]Flurossene [DCIT]Fluroxenum
Database identifiers
- CAS
406-90-6- PubChem CID
- 9844
- DTXSID
DTXSID5059957- ChEMBL
CHEMBL141446- ChEBI
CHEBI:134757- UNII
- FO7JHA3G03
- EC Number
- 206-977-1
- Nikkaji
- J1.530J
Properties
Computed structural properties
- XLogP
- 1.9
- Topological polar surface area
- 9.2 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 2
- Heavy atoms
- 8
- Formal charge
- 0
- Complexity
- 75.8
Experimental & physicochemical properties
Chemical ClassesOther Uses -> Waste Anesthetic Gases
SpringerMaterials PropertiesBoiling point
Density
1.14 (NIOSH, 2024) - Denser than water; will sink
1.14
Boiling Point
109 °F at 760 mmHg (NIOSH, 2024)
109 °F
Vapor Pressure
286 mmHg (NIOSH, 2024)
286.0 [mmHg]
286 mmHg
Physical Description
Volatile Liquid. Bp: 43 °C. Density: 1.14 g cm-3. Formerly used as an inhalation anesthetic.
Liquid. (inhalation anesthetic); Note: A gas above 109 degrees F; [NIOSH]
Liquid. [inhalation anesthetic] [Note: A gas above 109 °F.]
Physicochemical properties
- Boiling point
- 42 · 42-43°C
- Density
- 1 · 1,135 g/cm3
- refractive index
- 1.3192 · 1.3192
- Flash point
- -30 °C · -30°C
- storage temp.
- 2 · 2-8°C
- form
- A liquid
- Water Solubility
- 4 mg/L · 4mg/L(temperature not stated)
- Merck
- 14 · 14,4202
- BRN
- 1745876 · 1745876
- Henry's Law Constant
- 5.4 · 5.4×10-4 mol/(m3Pa) at 25℃, Fogg and Sangster (2003)
- Exposure limits
- 2 ppm · NIOSH: Ceiling 2 ppm(10.3 mg/m3)
- InChI
- InChI=1S/C4H5F3O/c1-2-8-3-4(5,6)7/h2H,1,3H2
- InChIKey
- DLEGDLSLRSOURQ-UHFFFAOYSA-N
- SMILES
- C=COCC(F)(F)F
- CAS DataBase Reference
- 406 · 406-90-6(CAS DataBase Reference)
- FDA UNII
- 7 JHA3G03 · FO7JHA3G03
- EPA Substance Registry System
- Ethene, (2,2,2-trifluoroethoxy)- (406-90-6)
- Symbol(GHS)
- 2 · GHS02,GHS05,GHS08
- Signal word
- Danger
- Hazard statements
- 225 · H225-H318-H341
- Precautionary statements
- 210 · P210-P260-P280-P308+P313
- Hazard Codes
- F,Xi
- Risk Statements
- 11 · 11-41-10
- Safety Statements
- 16 · 16-36-39-26
- RIDADR
- 1993 · 1993
- OEL
- 2 ppm · Ceiling: 2 ppm (10.3 mg/m3) [60-minute] [*Note: REL for exposure to waste anesthetic gas.]
- RTECS
- 4250000 · KO4250000
- Hazard Note
- Flammable
- TSCA
- TSCA listed
- HazardClass
- 3 · 3
- PackingGroup
- II
- HS Code
- 2909199090 · 2909199090
- Toxicity
- 3 pph/2H · mmo-sat 3 pph/2H MUREAV 58,183,78
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]
P203, P210, P233, P240, P241, P242, P243, P264+P265, P280, P303+P361+P353, P305+P354+P338, P317, P318, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 44 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
DOT LabelCombustible Liquid
Fire HazardsExcerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]:
Health HazardsExcerpt from NIOSH Pocket Guide for Fluoroxene:
Hazards SummarySee WASTE ANESTHETIC GASES
Reactive GroupEthers
Reactivity ProfileFLUOROXENE is non-flammable but combustible. Can form explosive mixtures with air. Reacts with strong oxidizing agents.
Flammable LimitsCombustible Liquid [potentially EXPLOSIVE!]
Air and Water ReactionsNo rapid reaction with air. No rapid reaction with water.
Hazard Classes and CategoriesFlam. Liq. 2 (100%)
Hazardous Reactivities and IncompatibilitiesNone reported
Safety & protection
Fire FightingExcerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]:
First Aid
Excerpt from NIOSH Pocket Guide for Fluoroxene:
(General first aid procedures)
Nonfire Spill ResponseExcerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]:
Isolation and EvacuationExcerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]:
Respirator RecommendationsImportant additional information about respirator selection
Permissible Exposure Limit (PEL)none
Recommended Exposure Limit (REL)C 2 ppm (10.3 mg/m3) [60-minute] [*Note: REL for exposure to waste anesthetic gas.]
Personal Protective Equipment (PPE)Excerpt from NIOSH Pocket Guide for Fluoroxene:
Immediately Dangerous to Life or Health (IDLH)N.D.
Toxicology
Target OrgansEyes, central nervous system
Adverse EffectsNeurotoxin - Acute solvent syndrome
Exposure Routesinhalation, ingestion, skin and/or eye contact
Signs and Symptomsirritation eyes; central nervous system depression, analgesia, anesthesia, convulsions, resp depression
Safety data
- OEL
- Ceiling: 2 ppm (10.3 mg/m3) [60-minute] [*Note: REL for exposure to waste anesthetic gas.]
- tsca
- TSCA listed
- rtecs
- KO4250000
- ridadr
- 1993
- hs_code
- 2909199090
- Toxicity
- mmo-sat 3 pph/2H MUREAV 58,183,78
- risk_code
- 11-41-10
- Signal word
- Danger
- Symbol(GHS)
- GHS02,GHS05,GHS08
- hazard_code
- F,Xi
- hazard_note
- Flammable
- safety_code
- 16-36-39-26
- hazard_class
- 3
- packing_group
- II
- Hazard statements
- H225-H318-H341
- Precautionary statements
- P210-P260-P280-P308+P313
Chemistry & industry
Uses & manufacturing
UsesFormerly used as a general anesthetic; [CAMEO]
General Manufacturing InformationEthene, (2,2,2-trifluoroethoxy)-: ACTIVE
Applications
DescriptionFluroxene , 2,2,2-trifluoro-1- vinyloxyethane, is a colorless liquid with a pungent odor. It is inflammable and, at concentrations above 4 %, explosive in air. Fluroxene (MAC3.4) generally is used in a mixture with oxygen and nitrous oxide. Several cases of liver damage have been observed.
UsesCa channel blocker, coronary vasodilator
General DescriptionVolatile Liquid. Bp: 43°C. Density: 1.14 g cm-3 . Formerly used as an inhalation anesthetic.
Upstream & downstream products
Upstream raw materials
Suppliers21 total
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
阿法埃莎（中国）化学有限公司400-6106006 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
MedChemexpress LLC021-58955995 · [email protected]
广东谦进化学试剂有限公司0751-2818792 13435114148 · [email protected]
BOC Sciences16314854226; +8616314854226 · [email protected]
HANGZHOU LEAP CHEM CO., LTD.+86-571-87711850 +86-15355479329 · [email protected]
广东翁江化学试剂有限公司0751-2886766 13927870850 · [email protected]
广东翁江化学试剂有限公司0751-2886750 13927877953 · [email protected]
广州市金华大化学试剂有限公司020-84383047 · [email protected]
Musechem+1-800-259-7612 · [email protected]
厦门盈融达化工有限公司+86-0592-6210733 · [email protected]
湖北摆渡化学有限公司027-59106051 13627137652 · [email protected]
山东氟晟达新材料科技有限责任公司15253121228 · [email protected]
陕西缔都医药化工有限公司029-029-029-81148696 18161915376 · [email protected]
湖北信康医药化工有限公司027-027-59308705 18871579363 · [email protected]
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.+8618950047208 · [email protected]
北京百灵威科技有限公司18210857532 18210857532 · [email protected]
上海皓元医药股份有限公司021-58950125 · [email protected]
河南威梯希化工科技有限公司0371-55135753 18003832934 · [email protected]
Additional notes
DefinitionChEBI: Fluroxene is an organofluorine compound.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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