Naphthoquine phosphate
Basic information
- CAS
173531-58-3- Standard SMILES
CC(C)(C)NCc1cc(Nc2ccnc3cc(Cl)ccc23)c2c(c1O)CCCC2.O=P(O)(O)O.O=P(O)(O)O- InChIKey
QTYPWHKJEDCDNH-UHFFFAOYSA-N- Molecular formula
- C24H34ClN3O9P2
- Average molar mass
- 605.9 g/mol
- Monoisotopic mass
- 605.1458814
Names & identifiers
- Preferred name
- Naphthoquine phosphate
- IUPAC
- 2-[(tert-butylamino)methyl]-4-[(7-chloroquinolin-4-yl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol;phosphoric acid
- English name
- NAPHTHOQUINE PHOSPHATE
- Molecular formula
- C24H31ClN3O5P
- Molecular weight
- 507.95
Names & synonyms
Naphthoquine phosphate173531-58-3M6M6AP4KAHDTXSID704317664-(7-Chloro-4-aminoquinoline)-2-tert-butylaminomethyl-5,6,7,8-4hydro-1-naphthol diphosphate1-Naphthalenol, 4-((7-chloro-4-quinolinyl)amino)-2-(((1,1-dimethylethyl)amino)methyl)-5,6,7,8-tetrahydro-, phosphate (1:2) (salt)RefChem:164763DTXCID60382596Naphthoquine (phosphate)Naphthoquine phosphate [WHO-DD]2-[(tert-butylamino)methyl]-4-[(7-chloroquinolin-4-yl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol;phosphoric acid2-((tert-Butylamino)methyl)-4-((7-chloroquinolin-4-yl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol bis(phosphate)
Show more names
Naphathoquine PhosphateNAPHTHOQUINE PHOSPHATE USP/EP/BPNaphthalene phosphoric acid phenol quinoline4-[(7-Chloro-4-quinolinyl)amino]-2-[[(tert-butyl)amino]methyl]-5,6,7,8-tetrahydro-1-naphthalenol phosphate1-Naphthalenol, 4-[(7-chloro-4-quinolinyl)amino]-2-[[(1,1-dimethylethyl)amino]methyl]-5,6,7,8-tetrahydro-, phosphate (1:2) (salt)
UNII-M6M6AP4KAHorb611920C24H34ClN3O9P2orb1709054SCHEMBL30684966MFCD25541748CS-0739DA-75989
Database identifiers
- CAS
173531-58-3- PubChem CID
- 9851774
- DTXSID
DTXSID70431766- UNII
- M6M6AP4KAH
Properties
Computed structural properties
- Topological polar surface area
- 213 Ų
- Hydrogen bond donors
- 9
- Hydrogen bond acceptors
- 12
- Rotatable bonds
- 5
- Heavy atoms
- 39
- Formal charge
- 0
- Complexity
- 588
Physicochemical properties
- storage temp.
- 2 · under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- Soluble in DMSO
- form
- Powder
- color
- Light yellow to yellow
- FDA UNII
- 6 M6AP4KAH · M6M6AP4KAH
Chemistry & industry
Applications
UsesNaphthoquine phosphate is a potent and orally active antimalarial agent. Naphthoquine phosphate has thorough killing function for various schizonts of plasmodia, including resistance of P. falciparum to Chloroquine[1][2].
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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