Basic information
- CAS
193273-69-7- Standard SMILES
CN1N=C2CCN(C(=O)[C@@H](COCc3ccccc3)NC(=O)C(C)(C)N)C[C@@]2(Cc2ccccc2)C1=O.O=C(O)[C@H](O)[C@@H](O)C(=O)O- InChIKey
MJGRJCMGMFLOET-MYPSAZMDSA-N- Molecular formula
- C32H41N5O10
- Average molar mass
- 655.7 g/mol
- Monoisotopic mass
- 655.28534252
Overview
See also: Capromorelin (has active moiety).
Names & identifiers
- Preferred name
- Capromorelin Tartrate
- IUPAC
- N-[(2R)-1-[(3aR)-3a-benzyl-2-methyl-3-oxo-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]-1-oxo-3-phenylmethoxypropan-2-yl]-2-amino-2-methylpropanamide;(2R,3R)-2,3-dihydroxybutanedioic acid
- English name
- CaproMorelin Tartrate
- Molecular formula
- C32H41N5O10
- Molecular weight
- 655.71
Names & synonyms
Capromorelin tartrate193273-69-7Capimorelin tartrateUNII-4150VMF5EPCP 424391-18CP-424,391-184150VMF5EPCP-424391-182-Amino-N-((1R)-1-(((3aR)-3a-benzyl-2,3,3a,4,6,7-hexahydro-2-methyl-3-oxo-5H-pyrazolo(4,3-c)pyridin-5-yl)carbonyl)-2-(benzyloxy)ethyl)-2-methylpropionamide L-(+)-tartrate (1:1)PROPANAMIDE, 2-AMINO-N-(2-(2,3,3A,4,6,7-HEXAHYDRO-2-METHYL-3-OXO-3A-(PHENYLMETHYL)-5H-PYRAZOLO(4,3-C)PYRIDIN-5-YL)-2-OXO-1-((PHENYLMETHOXY)METHYL)ETHYL)-2-METHYL-, (R-(R*,R*))-, (R-(R*,R*))-2,3-DIHYDROXYBUTANEDIOATE (1:1)RefChem:57559Capromorelin (Tartrate)
Show more names
CS-2136CP-424391 tartrateCaproorelin tartrateCapromorelin L-TartrateCP-424391 TARTRATECapromorelin tartrate (CP-424,391)Capromorelin Tartrate, 10 mM in DMSOInhibitor,Growth hormone secretagogue receptor,GHSR,Capromorelin,inhibit,Capromorelin Tartrate
Capromorelin tartrate [USAN]Capromorelin tartrate (USAN)N-[(2R)-1-[(3aR)-3a-benzyl-2-methyl-3-oxo-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]-1-oxo-3-phenylmethoxypropan-2-yl]-2-amino-2-methylpropanamide;(2R,3R)-2,3-dihydroxybutanedioic acid193273-69-7 (tartrate)Capromorelin?Propanamide, 2-Amino-N-[(1R)-2-[(3aR)-2,3,3a,4,6,7-hexahydro-2-methyl-3-oxo-3a-(phenylmethyl)-5H-pyrazolo[4,3-c]pyridin-5-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methyl-, (2R,3R)-2,3-dihydroxybutanedioate; CP-424391-18MFCD25977748orb1218538
Properties
Computed structural properties
- Topological polar surface area
- 232 Ų
- Hydrogen bond donors
- 6
- Hydrogen bond acceptors
- 12
- Rotatable bonds
- 12
- Heavy atoms
- 47
- Formal charge
- 0
- Complexity
- 1,010
Experimental & physicochemical properties
Animal DrugsEMA approved medicines: Veterinary medicine
Physicochemical properties
- Melting point
- 150 oC · >150oC (dec.)
- storage temp.
- -20 °C · Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Light Yellow
- Water Solubility
- 2 O: · H2O: 20mg/mL, clear
- Stability
- Hygroscopic
- InChIKey
- MJGRJCMGMFLOET-GTNBBHPYNA-N
- SMILES
- [C@H](O)(C(=O)O)[C@@H](O)C(=O)O.C(C1C=CC=CC=1)[C@]12C(N(C)N=C1CCN(C(=O)[C@H](NC(=O)C(N)(C)C)COCC1C=CC=CC=1)C2)=O |&1:0,5,17,28,r|
- FDA UNII
- 4150 VMF5EP · 4150VMF5EP
- UNSPSC Code
- 51111800 · 51111800
- NACRES
- 77 · NA.77
- Symbol(GHS)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Safety data
- wgk
- WGK 3
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Storage Class
- 11 - Combustible Solids
- target organs
- Respiratory system
- Hazard statements
- H315-H319-H335
- Hazard Classifications
- Eye Irrit. 2Skin Irrit. 2STOT SE 3
- Precautionary statements
- P261-P264-P271-P280-P302+P352-P305+P351+P338
Chemistry & industry
Applications
UsesTreatment and prevention of frailty; treatment of congestive heart failure; treatment of catabolic illness (growth hormone secretagogue).
UsesCapromorelin Tartrate acts as a reagent used in the preparation of pyrazolopyridine amide growth hormone secretagogues for treatment of fibromyalgia
Suppliers59 total
北京华美互利生物化工010-56205725 · [email protected]
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
成都超九八生物科技有限公司13348960310 13348960310 · [email protected]
武汉敬康恩生物医药科技有限公司13720134139 086-15871494362 13720134139 · [email protected]
咸宁深蓝生物医药研发有限公司18171815831 · [email protected]
杭州品高化工有限公司0571-87658025 · [email protected]
南京林叶化学试剂有限公司13376084917 13376082704 · [email protected]
陕西缔都化学有限公司029-029-81123119 17391733320 · [email protected]
湖北科乐精细化工有限公司027-59101668 19945030958 · [email protected]
上海波以尔化工有限公司[email protected]
欧利希（湖北）医药科技有限公司17316404525 17316404525 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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