Basic information
- CAS
12069-68-0- Standard SMILES
O.O.O=C(O)O.[Co].[Co]- InChIKey
SNLQNWHKVIOALT-UHFFFAOYSA-N- Molecular formula
- CH6Co2O5
- Average molar mass
- 215.92 g/mol
- Monoisotopic mass
- 215.88791
Overview
Cobalt(II) carbonate hydroxide (1:1) is a chemical compound of cobalt. Cobalt is a metallic element with the atomic number 27. It is found naturally in rocks, soil, water, plants, and animals. In small amounts cobalt is an essential element for life, as it is part of vitamin B12. However, excess exposure is known to exhibit toxic effects. (L29, L30)
Names & identifiers
- Preferred name
- Cobalt(II) carbonate hydroxide (1:1)
- IUPAC
- carbonic acid;cobalt;dihydrate
Names & synonyms
(Carbonato)dihydroxydicobaltCobalt(II) carbonate hydroxide (1:1)RefChem:1082072CARBONIC ACID DICOBALT DIHYDRATECobalt, (carbonato)dihydroxydi-(mu-(Carbonato(2-)-O:O'))dihydroxydicobaltEINECS 235-112-0Cobalt carbonate hydroxide (Co2CO3(OH)2)Cobalt, (mu-(carbonato(2-)-O:O'))dihydroxydi-
Database identifiers
- CAS
12069-68-0- PubChem CID
- 98531
Properties
Computed structural properties
- Topological polar surface area
- 59.5 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 0
- Heavy atoms
- 8
- Formal charge
- 0
- Complexity
- 33.4
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety & protection
Minimum Risk LevelChronic Inhalation: 0.0001 mg/m3 (L134)
Intermediate Oral: 0.01 mg/kg/day (L134)
Toxicology
TreatmentTreatment of cobalt poisoning is symptomatic. (L29)
Health EffectsExposure to high amount of cobalt can cause heart, lung, kidney, and liver damage. Skin contact is known to result in contact dermatitis. Cobalt may also have mutagenic and carcinogenic effects. (L29, L30)
Exposure RoutesInhalation (L29) ; oral (L29) ; dermal (L29)
Toxicity Summary
Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, causing increased lipid peroxidation, DNA damage, and inducing certain enzymes that lead to cell apoptosis. Cobalt has also been shown to block inorganic calcium channels, possibly impairing neurotransmission. Cobalt can also chelate lipoic acids, impairing oxidation of pyruvate or fatty acids. In addition, cobalt may inhibit DNA repair by interacting with zinc finger DNA repair proteins, and has also been shown to inhibit heme synthesis and glucose metabolism. Cobalt may activate specific helper T-lymphocyte cells and interact directly with immunologic proteins, such as antibodies (IgA and IgE) or Fc receptors, resulting in immunosensitization. (L29)
Signs and SymptomsCobalt inhalation can cause asthma-like breathing problems. Skin contact is known to result in contact dermatitis, which is characterized by irritation and rashes. Ingesting large amounts of cobalt may cause nausea and vomiting. (L2090)
Carcinogen Classification2B, possibly carcinogenic to humans. (L135)
Chemistry & industry
Pharmacology
Metabolism/Metabolites
Cobalt is absorbed though the lungs, gastrointestinal tract, and skin. Since it is a component of the vitamin B12 (cyanocobalamin), it is distributed to most tissues of the body. It is transported in the blood, often bound to albumin, with the highest levels being found in the liver and kidney. Cobalt is excreted mainly in the urine and faeces. (L29)
Related reactions
0 records
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Compound notes
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