Tetrazolium blue
Basic information
- CAS
1871-22-3- Standard SMILES
COc1cc(-c2ccc(-[n+]3nc(-c4ccccc4)nn3-c3ccccc3)c(OC)c2)ccc1-[n+]1nc(-c2ccccc2)nn1-c1ccccc1.[Cl-].[Cl-]- InChIKey
MUUHXGOJWVMBDY-UHFFFAOYSA-L- Molecular formula
- C40H32N8O2.2Cl
- Average molar mass
- 727.6 g/mol
- Monoisotopic mass
- 726.2025277
Overview
Tetrazolium blue is an organic chloride salt having tetrazolium blue(1+) as the counterion. It has a role as a dye. It contains a tetrazolium blue(2+).
Names & identifiers
- Preferred name
- Tetrazolium blue
- IUPAC
- 2-[4-[4-(3,5-diphenyltetrazol-2-ium-2-yl)-3-methoxyphenyl]-2-methoxyphenyl]-3,5-diphenyltetrazol-2-ium dichloride
- English name
- Tetrazolium Blue Chloride
- Molecular formula
- C40H32Cl2N8O2
- Molecular weight
- 727.64
Names & synonyms
1871-22-3Tetrazolium blueBlue tetrazoliumBlue tetrazolium chlorideDitetrazolium chlorideDimethoxy neotetrazolium4-Anisyltetrazolium bluep-anisyltetrazolium blueEINECS 217-488-83,3'-Dianisolebis(4,4'-(3,5-diphenyl)tetrazolium chloride)NSC 276230468TBH014
Show more names
BTCBTTZBTVBTMFTurexBT(dye)/BTC/BT
3,3'-(3,3'-Dimethoxy-4,4'-biphenylene)bis(2,5-diphenyl-2H-tetrazolium) chlorideTETRAZOLIUM BLUE [MI]AI3-50892CHEBI:75198DTXSID70889369NSC-276233,3'-Dianisolebis(4,4'-(3,5-diphenyl)tetrazoliumchloride)2H-Tetrazolium, 2,2'-(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis[3,5-diphenyl-, dichloride
Database identifiers
- CAS
1871-22-3- PubChem CID
- 9853362
- DTXSID
DTXSID70889369
Properties
Computed structural properties
- Topological polar surface area
- 87.6 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 8
- Rotatable bonds
- 9
- Heavy atoms
- 52
- Formal charge
- 0
- Complexity
- 951
Physicochemical properties
- Melting point
- 255 °C · 255 °C (dec.)(lit.)
- Density
- 1.9137 · 1.9137 (rough estimate)
- refractive index
- 1.6 · 1.6000 (estimate)
- storage temp.
- room temp
- solubility
- Soluble in water;freely soluble ethanol, methanol, chloroform; insoluble in acetone, ether, ethyl acetate
- form
- crystals or powder
- color
- Lemon yellow
- Odor
- Odorless
- biological source
- bovine nose
- Water Solubility
- Soluble in hot water (5 mg/ml), methanol (50 mg/ml), ethanol, and chloroform. Insoluble in acetone.
- λmax
- 253 nm · 253 nm
- Merck
- 14 · 14,9244
- BRN
- 3894077 · 3894077
- Stability
- Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
- Major Application
- microbiology
- Biological Applications
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H350 (100%): May cause cancer [Danger Carcinogenicity]
P203, P280, P318, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 43 reports by companies from 3 notifications to the ECHA C&L Inventory.
Hazard information
Regulatory Information
Chemical: 2H-Tetrazolium, 3,3'-(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis[2,5-diphenyl-, dichloride
Hazard Traits - Bioaccumulation; Environmental Persistence
4-Anisyltetrazolium blue: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and CategoriesCarc. 1B (100%)
Safety data
- F
- 3-8-10
- PPE
- Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
- wgk
- 3
- tsca
- TSCA listed
- rtecs
- XF8050000
- hs_code
- 29339990
- risk_code
- 45-36/37/38
- Signal word
- Danger
- Symbol(GHS)
- GHS08
- hazard_code
- T,Xi
- safety_code
- 53-45-36-26-24/25
- Storage Class
- 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects
Chemistry & industry
Uses & manufacturing
General Manufacturing Information2H-Tetrazolium, 2,2'-(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis[3,5-diphenyl-, chloride (1:2): ACTIVE
Applications
UsesTetrazolium Blue Chloride is used for its anti-plasmodium activity. Also used in the study of inhibition of diphenyltetrazolium bromide (MTT) reduction by β-amyloid peptides resulting in neurodegenerative manifestations. Dyes and metabolites.
UsesFor research in seed germination, as stain for bacteria and molds, in histochemical studies, to demonstrate oxidation-reduction enzymes in normal and cancerous tissues. See also Triphenyltetrazolium Chloride.
Additional notes
DefinitionChEBI: An organic chloride salt having tetrazolium blue(1+) as the counterion.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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