Basic information
- CAS
135239-65-5- Standard SMILES
CCCCCCCCCCOc1ccc(C(=O)Nc2cc(C(=O)NCCCC)ccc2SC)cc1- InChIKey
OZMWNRSILHTVFV-UHFFFAOYSA-N- Molecular formula
- C29H42N2O3S
- Average molar mass
- 498.7 g/mol
- Monoisotopic mass
- 498.29161438
Overview
structure in first source
Names & identifiers
- Preferred name
- RP-64477
- IUPAC
- N-butyl-3-[(4-decoxybenzoyl)amino]-4-methylsulfanylbenzamide
- English name
- RP-64477
- Molecular formula
- C29H42N2O3S
- Molecular weight
- 498.72
Names & synonyms
RP-64477135239-65-5n-Butyl-3-(4-decyloxybenzamido)-4-(methylthio)benzamideK10EML8B3SN'-Butyl-4-(decyloxy)-4'-(methylthio)-N,3'-bibenzamideRP 64477Benzamide, n-butyl-3-((4-(decyloxy)benzoyl)amino)-4-(methylthio)-N-butyl-3-(p-decyloxybenzamido)-4-(methylthio)benzamideRefChem:180024N-butyl-3-(4-(decyloxy)benzamido)-4-(methylthio)benzamideCHEMBL5542126N-butyl-3-[(4-decoxybenzoyl)amino]-4-methylsulfanylbenzamide
Show more names
RP-64477, 10 mM in DMSOBenzamide, N-butyl-3-[[4-(decyloxy)benzoyl]amino]-4-(methylthio)-RP-64477,Diglyceride acyltransferase,RP 64477,inhibit,mono- acylglycerol acyltransferase,Acyltransferase,Inhibitor,acyl-CoA:cholesterol acyltransferase,Diacylglycerol acyltransferase
rp64477UNII-K10EML8B3Sorb1299045SCHEMBL6940849C29H42N2O3SKFA23965N-butyl-3-[(4-decoxybenzoyl)amino]-4-methylsulfanyl-benzamideBDBM50637888
Properties
Computed structural properties
- XLogP
- 8.3
- Topological polar surface area
- 92.7 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 17
- Heavy atoms
- 35
- Formal charge
- 0
- Complexity
- 580
Experimental & physicochemical properties
LogP5.2
Physicochemical properties
- storage temp.
- -20 °C · Store at -20°C
- solubility
- 8.33 mg/mL · DMSO: 8.33 mg/mL (16.70 mM)
- form
- Solid
- color
- White to off-white
- FDA UNII
- 10 EML8B3S · K10EML8B3S
Chemistry & industry
Applications
UsesRP-64477 is a potent inhibitor of the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT).
Suppliers30 total
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
United Life Science020-82099279 18988941402 · [email protected]
銳迪國際科技有限公司18024082417 · [email protected]
MedChemexpress LLC021-58955995 · [email protected]
湖北魏氏化学试剂股份有限公司17771898297 13125137661 · [email protected]
四川省维克奇生物科技有限公司028-81700200 18116577057 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
斯派螺（武汉）药物研发有限公司[email protected]
苏州美石生物科技有限公司1173954148q · [email protected]
晶墨(厦门)生物科技有限公司13621943973; 13621943973 · [email protected]
上海阿拉丁生化科技股份有限公司6206333 13167063860 · [email protected]
上海源叶生物科技有限公司13636370518 · [email protected]
Related reactions
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No reaction records under the current filter.
Compound notes
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