Basic information
- CAS
83535-74-4- Standard SMILES
CC(=O)Nc1ccc(O)cc1.CC(=O)Oc1ccccc1C(=O)O.Cn1c(=O)c2c(ncn2C)n(C)c1=O- InChIKey
BKMBGNWZSQNIKU-UHFFFAOYSA-N- Molecular formula
- C25H27N5O8
- Average molar mass
- 525.5 g/mol
Overview
Acetaminophen/Aspirin/Caffeine is a commercial combination preparation by Novartis containing acetaminophen, aspirin, and caffeine with analgesic activity. Acetaminophen exerts antipyretic and analgesic activities by inhibiting prostaglandin synthesis while aspirin, a salicylate, inhibits cyclooxygenases (COX) with anti-inflammatory, antipyretic and analgesic properties. Caffeine is a central nervous system stimulant and causes constriction of dilated cerebral blood vessels. Excedrin is used for the relief and treatment of migraine and tension headaches.
Names & identifiers
- Preferred name
- Acetaminophen; Aspirin; Caffeine
- IUPAC
- 2-acetyloxybenzoic acid;N-(4-hydroxyphenyl)acetamide;1,3,7-trimethylpurine-2,6-dione
Names & synonyms
Acetaminophen / aspirin / caffeineSeedalmerkArthritenExtraprinArthritenMaxExcedrinMigrainemigraine formulaDolex ForteHeadache FormulaExcedrin MigraineXpect Pain AwayPain Free Plus
Show more names
Medique Pain OffPain Reliever 2ConRx pain RelieverHeadache, Circle KCove Migraine ReliefDOLODOLSohMed Pain RelieverExcedrinExtra Strength
Database identifiers
- CAS
83535-74-4- PubChem CID
- 9871508
Properties
Computed structural properties
- Topological polar surface area
- 171 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 9
- Rotatable bonds
- 4
- Heavy atoms
- 38
- Formal charge
- 0
- Complexity
- 644
Experimental & physicochemical properties
Human DrugsFDA approved drugs -> Active ingredient
Safety & regulation
Toxicology
Adverse EffectsCaffeine
Toxicity SummaryCaffeine
Related reactions
1 records
Compound notes
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