Basic information
- CAS
375345-95-2- Standard SMILES
CC(C)S(=O)(=O)NC[C@H](C)c1ccc(-c2ccc(CCNS(C)(=O)=O)cc2)cc1- InChIKey
ULRDYYKSPCRXAJ-KRWDZBQOSA-N- Molecular formula
- C21H30N2O4S2
- Average molar mass
- 438.6 g/mol
- Monoisotopic mass
- 438.16469979
Overview
Mibampator has been used in trials studying the treatment of Alzheimer's Disease.
Names & identifiers
- Preferred name
- Mibampator
- IUPAC
- N-[(2R)-2-[4-[4-[2-(methanesulfonamido)ethyl]phenyl]phenyl]propyl]propane-2-sulfonamide
- English name
- MibaMpator
- Molecular formula
- C21H30N2O4S2
- Molecular weight
- 438.6
Names & synonyms
MIBAMPATOR375345-95-2LY451395LY 451395LY-451395A9V5BW73UUDTXSID20190977N-((2R)-2-(4'-(2-((Methylsulfonyl)amino)ethyl)biphenyl-4-yl)propyl)propane-2-sulfonamide2-Propanesulfonamide, N-((2R)-2-(4'-(2-((methylsulfonyl)amino)ethyl)(1,1'-biphenyl)-4-yl)propyl)-2-PROPANESULFONAMIDE, N-[(2R)-2-[4'-[2-[(METHYLSULFONYL)AMINO]ETHYL][1,1'-BIPHENYL]-4-YL]PROPYL]-mibampatorumRefChem:925842
Show more names
CS-1234Mibampator?(LY451395)Mibampator, 10 mM in DMSO[(2R)-2-[4-[4-[2-[(Methylsulfonyl)amino]ethyl]phenyl]phenyl]propyl][(1-methylethyl)sulfonyl]amine
DTXCID60113468N-((2R)-2-(4'-(2-methanesulfonamidoethyl)-(1,1'-biphenyl)-4-yl)propyl)propane-2-sulfonamide(R)-N-(2-(4'-(2-(Methylsulfonamido)ethyl)-[1,1'-biphenyl]-4-yl)propyl)propane-2-sulfonamideN-[(2R)-2-[4-[4-[2-(methanesulfonamido)ethyl]phenyl]phenyl]propyl]propane-2-sulfonamideCHEMBL1277001MFCD18251566UNII-A9V5BW73UUN-[(2R)-2-[4-[4-[2-(methylsulfonylamino)ethyl]phenyl]phenyl]propyl]propane-2-sulfonamide
Properties
Computed structural properties
- XLogP
- 3.4
- Topological polar surface area
- 109 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 10
- Heavy atoms
- 29
- Formal charge
- 0
- Complexity
- 679
Experimental & physicochemical properties
DrugsPharmaceuticals -> Listed in ZINC15
Physicochemical properties
- Boiling point
- 609.4 · 609.4±65.0 °C(Predicted)
- Density
- 1.205 · 1.205±0.06 g/cm3(Predicted)
- storage temp.
- -20 °C · Store at -20°C
- solubility
- Soluble in DMSO
- form
- Powder
- pka
- 11.05 · 11.05±0.40(Predicted)
- color
- White to off-white
- FDA UNII
- 9 V5BW73UU · A9V5BW73UU
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H312-H332
- Precautionary statements
- 261 · P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H312-H332
- Precautionary statements
- P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501
Chemistry & industry
Applications
UsesMibampator (LY451395) is a potent and highly selective potentiator of the AMPA receptors.
Suppliers29 total
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
上海冬洋生物科技有限公司0512-13601744364 13601744364 · [email protected]
江苏艾康生物医药研发有限公司025-5885952 15955137747 · [email protected]
MedBio脉铂医药021-69568360 18916172912 · [email protected]
銳迪國際科技有限公司18024082417 · [email protected]
上海毕得医药科技股份有限公司400-164-7117 18317119277 · [email protected]
四川省维克奇生物科技有限公司028-81700200 18116577057 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
上海楼岚生物科技有限公司021-52996696，15000506266 15000506266
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
斯派螺（武汉）药物研发有限公司[email protected]
广州市齐云生物技术有限公司020-61288194 61288195 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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