Basic information
- CAS
434-07-1- Standard SMILES
C[C@]12CC(=CO)C(=O)C[C@@H]1CC[C@@H]1[C@@H]2CC[C@@]2(C)[C@H]1CC[C@]2(C)O- InChIKey
ICMWWNHDUZJFDW-IYRCEVNGSA-N- Molecular formula
- C21H32O3
- Average molar mass
- 332.5 g/mol
- Monoisotopic mass
- 332.23514488
Names & identifiers
- Preferred name
- (5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-2-(hydroxymethylene)-10,13,17-trimethyl-1,4,5,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
- IUPAC
- (5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-2-(hydroxymethylidene)-10,13,17-trimethyl-1,4,5,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
- English name
- Oxymetholone
- Molecular formula
- C21H32O3
- Molecular weight
- 332.48
Names & synonyms
SCHEMBL145160(5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-2-(hydroxymethylene)-10,13,17-trimethyl-1,4,5,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-oneCPD000058877PD00293317ss-Hydroxy-2-hydroxymethylen-17a-methyl-5a-androstan-3-onAndrostan-3-one, 17-hydroxy-2-(hydroxymethylene)-17methyl-, (5.alpha.,17.beta.)OXYCLOZANIDEAnadrolAnapolonOximetolonaOxyMetholonoxymethalone
Show more names
OxyMetholone (Anadrol)anapalonMethabolANASTERONE
Database identifiers
- CAS
434-07-1- PubChem CID
- 9902
Properties
Computed structural properties
- XLogP
- 4.4
- Topological polar surface area
- 57.5 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 0
- Heavy atoms
- 24
- Formal charge
- 0
- Complexity
- 596
Physicochemical properties
- Melting point
- 172 · 172-180°C
- alpha
- 34 · 34 º
- Boiling point
- 409.59 °C · 409.59°C (rough estimate)
- Density
- 1.0834 · 1.0834 (rough estimate)
- refractive index
- 38 ° · 38 ° (C=1, CHCl3)
- storage temp.
- 2 · 2-8°C
- solubility
- 2 O: · H2O: ≤0.5 mg/mL
- pka
- 5.28 · 5.28±0.70(Predicted)
- form
- solid
- color
- white to light yellow
- Water Solubility
- 0.1 g/100 · <0.1 g/100 mL at 23 ºC
- Merck
- 6967 · 6967
- Henry's Law Constant
- 6.6 · 6.6×103 mol/(m3Pa) at 25℃, HSDB (2015)
- Stability
- Stability May be light sensitive. Combustible. Incompatible with strong oxidizing agents.
- Major Application
- pharmaceutical
- InChI
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- wgk
- 3
- rtecs
- BV8060000
- hs_code
- 29372900
- Toxicity
- TDLo orl-hmn: 46 mg/kg/14W-I:LIV JAMAAP 240,243,78
- risk_code
- 40-63
- Signal word
- Warning
- Symbol(GHS)
- GHS08
- hazard_code
- T,Xn
- safety_code
- 53-22-26-36/37/39-36
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H351-H361
- Hazard Classifications
- Carc. 2Repr. 2
- Precautionary statements
- P201-P308+P313
- Hazardous Substances Data
- 434-07-1(Hazardous Substances Data)
Chemistry & industry
Applications
DescriptionOxymetholone is a synthetic, orally active anabolic-androgenic steroid (AAS) and 17α-methylated derivative of dihydrotestosterone (DHT). It is mainly used for the treatment of osteroporosis and anemia (low red blood cell count). It can also stimulate the muscle growth in malnourished or underdeveloped patients. It also has the potential to treat the HIV wasting syndrome. Oxymetholone can also lead to an even buildup in strength, which is its secondary characteristics, making it an excellent steroid to be coupled with other anabolic steroids to yield synergetic effect.
UsesOxymetholone is used in treatment of myelofibrosis and myelosuppression. This drug can provoke bone marrow cells and rise the blood cells in the peripheral blood vessels. It has been approved by the US Food and Drug Administration for the treatment of anemia caused by deficient red cell production. It is effective in catabolic states, replacement of male sex steroids in men who have androgen deficiency, and in eugonadal male and female patients with acquired immunodeficiency syndrome-associated wasting.
General DescriptionOxymetholone is an odorless white to creamy white crystalline powder. It is approved for the treatment of various anemias.
Upstream & downstream products
Upstream raw materials
Suppliers100 total
国药集团化学试剂有限公司86-21-63210123 · [email protected]
Shanghai Biolang Biotechnology Co., Ltd.+86-15970428662 +86-13397199602 · [email protected]
艾吉析科技（上海）有限公司17717235263 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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