Basic information
- Standard SMILES
O=C(O)C1CSCN1- InChIKey
DZLNHFMRPBPULJ-UHFFFAOYSA-N- Molecular formula
- C4H7NO2S
- Average molar mass
- 133.17 g/mol
Overview
Thioproline is a sulfur-containing amino acid that is proline in which the methylene group at position 4 is replaced by a sulfur atom. It has a role as an antioxidant, an antidote and a hepatoprotective agent. It is a sulfur-containing amino acid, a thiazolidinemonocarboxylic acid and a non-proteinogenic alpha-amino acid. It is a tautomer of a thioproline zwitterion.
Names & identifiers
- Preferred name
- Timonacic
- IUPAC
- 1,3-thiazolidine-4-carboxylic acid
Names & synonyms
TimonacicThiazolidine-4-carboxylic acid444-27-94-THIAZOLIDINECARBOXYLIC ACID1,3-Thiazolidine-4-carboxylic acidDetoxepaHepalidineThioprolineThiaprolineTiazolidinNorgamemDL-Thiaproline
Show more names
4-CarboxythiazolidineNorgamenTimonacicoHeparegenTimonacicumNSC-25855HepacomDL-Thiazolidinecarboxylic acid
Database identifiers
- CAS
444-27-9- PubChem CID
- 9934
- ChEMBL
CHEMBL1235440、CHEMBL358722- ChEBI
CHEBI:64564- UNII
- E5913T3IBL
- EC Number
- 207-146-6
- Nikkaji
- J5.746K
Properties
Computed structural properties
- XLogP
- -2.3
- Topological polar surface area
- 74.6 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 1
- Heavy atoms
- 8
- Formal charge
- 0
- Complexity
- 106
Safety & regulation
GHS classification
GHS Classification
Warning
H302 (97.7%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P264+P265, P270, P280, P301+P317, P305+P351+P338, P330, P337+P317, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 44 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (97.7%)
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
Agents counteracting or neutralizing the action of POISONS.
Substances that inhibit or prevent the proliferation of NEOPLASMS.
Naturally occurring or synthetic substances that inhibit or retard oxidation reactions. They counteract the damaging effects of oxidation in animal tissues.
Uses & manufacturing
Household ProductsInformation on 1 consumer products that contain Timonacic in the following categories is provided:
General Manufacturing Information4-Thiazolidinecarboxylic acid: INACTIVE
Related reactions
159 records
Linked notes
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