Mometasone Furoate EP Impurity E
Basic information
- CAS
1370190-33-2- Standard SMILES
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](OC(=O)c3ccco3)C[C@]2(C)[C@@]1(OC(=O)c1ccco1)C(=O)CCl- InChIKey
MJDGUHJEIVTMQZ-VYYCQGSCSA-N- Molecular formula
- C32H32Cl2O8
- Average molar mass
- 615.5 g/mol
- Monoisotopic mass
- 614.1474234
Names & identifiers
- Preferred name
- Mometasone Furoate EP Impurity E
- IUPAC
- [(8S,9R,10S,11S,13S,14S,16R,17R)-9-chloro-17-(2-chloroacetyl)-17-(furan-2-carbonyloxy)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-11-yl] furan-2-carboxylate
- English name
- 11,17-Difuroate MoMetasone Furoate
- Molecular formula
- C32H32Cl2O8
- Molecular weight
- 615.5
Names & synonyms
1370190-33-2Mometasone Furoate EP Impurity E11,17-Difuroate Mometasone FuroatePM5X8N7NWYMometasone-11,17-difuroate11,17-Difuroate Mometasone FuroateMometasone Furoate Impurity E(8S,9R,10S,11S,13S,14S,16R,17R)-9-chloro-17-(2-chloroacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-11,17-diyl bis(furan-2-carboxylate)[(8S,9R,10S,11S,13S,14S,16R,17R)-9-Chloro-17-(2-chloroacetyl)-17-(furan-2-carbonyloxy)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-11-yl] furan-2-carboxylate(11beta,16alpha)-9,21-Dichloro-11,17-bis[(2-furanylcarbonyl)oxy]-16-methylpregna-1,4-diene-3,20-dione(11beta,16alpha)-9,21-Dichloro-11,17-bis((2-furanylcarbonyl)oxy)-16-methylpregna-1,4-diene-3,20-dione(11beta,16alpha)-9,21-Dichloro-11,17-bis[(2-furanylcarbonyl)oxy]-16-methylpregna-1,4-diene-3,20-dione; 9,21-Dichloro-16alpha-methyl-3,20-dioxopregna-1,4-diene-11beta,17-diyl bis(furan-2-carboxylate); Mometasone Furoate Impurity E9,21-Dichloro-16alpha-methyl-3,20-dioxopregna-1,4-diene-11beta,17-diyl Bis(furan-2-carboxylate)
Properties
Computed structural properties
- XLogP
- 5.5
- Topological polar surface area
- 113 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 8
- Rotatable bonds
- 8
- Heavy atoms
- 42
- Formal charge
- 0
- Complexity
- 1,250
Physicochemical properties
- Melting point
- 237 · 237-247°C (dec.)
- storage temp.
- Refrigerator, Under Inert Atmosphere
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly, Sonicated, Heated)
- form
- Solid
- color
- White to Pale Yellow
- Major Application
- pharmaceutical
- FDA UNII
- 5 X8N7NWY · PM5X8N7NWY
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 280 · P280-P305+P351+P338
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P280-P305+P351+P338
Chemistry & industry
Applications
Uses11,17-Difuroate Mometasone Furoate (Mometasone EP Impurity E) is an impurity of Mometasone Furoate, a topical corticosteroid used as an anti-inflammatory.
Uses11,17-Difuroate Mometasone Furoate is the impurity of Mometasone Furoate, a topical corticosteroid used as an anti-inflammatory.
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Compound notes
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