Basic information
- CAS
3918-84-1- Standard SMILES
N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)O- InChIKey
FYYSIASRLDJUNP-WHFBIAKZSA-N- Molecular formula
- C9H14N2O7
- Average molar mass
- 262.22 g/mol
- Monoisotopic mass
- 262.08010079
Overview
Glu-Asp is a dipeptide composed of L-glutamic acid and L-aspartic acid joined by a peptide linkage. It has a role as a metabolite. It is functionally related to a L-glutamic acid and a L-aspartic acid.
Names & identifiers
- Preferred name
- L-alpha-Glutamyl-L-aspartic acid
- IUPAC
- (2S)-2-[[(2S)-2-amino-4-carboxybutanoyl]amino]butanedioic acid
- English name
- H-Glu-Asp-OH
- Molecular formula
- C9H14N2O7
- Molecular weight
- 262.22
Names & synonyms
3918-84-1alpha-Glutamylaspartic acidalpha-Glu-aspL-alpha-Glutamyl-L-aspartic acid(2S)-2-[[(2S)-2-amino-4-carboxybutanoyl]amino]butanedioic acid(2S)-2-(((2S)-2-amino-4-carboxybutanoyl)amino)butanedioic acidRefChem:924386H-GLU-ASP-OHGlu-Asp-OHGlu-Aspglutamylaspartic acidMFCD00037308
Show more names
VesiluteL-ALPHA-GLU-L-ASPVesilute (Glu-Asp)Glu-Asp-OH≥ 98% (TLC)L-A-GLUTAMYL-L-ASPARTIC ACIDL-α-Glutamyl-L-aspartic acid
(S)-2-((S)-2-Amino-4-carboxybutanamido)succinic acidL-Glutamyl-L-aspartic acid38Y324JU2XC9H14N2O7alpha-L-Glu-L-AspED dipeptideE-D DipeptideNSC-186905
Database identifiers
- CAS
3918-84-1- PubChem CID
- 99716
- ChEBI
CHEBI:73503- UNII
- 38Y324JU2X
Properties
Computed structural properties
- XLogP
- -4.6
- Topological polar surface area
- 167 Ų
- Hydrogen bond donors
- 5
- Hydrogen bond acceptors
- 8
- Rotatable bonds
- 8
- Heavy atoms
- 18
- Formal charge
- 0
- Complexity
- 355
Experimental & physicochemical properties
LogP-4.64
Physical DescriptionSolid
Physicochemical properties
- Melting point
- 150 · 150-153 °C (decomp)
- Boiling point
- 608.2 · 608.2±55.0 °C(Predicted)
- Density
- 1.53 · 1.530±0.06 g/cm3(Predicted)
- storage temp.
- -15 °C · -15°C
- pka
- 2.87 · 2.87±0.10(Predicted)
- FDA UNII
- 38 Y324JU2X · 38Y324JU2X
Chemistry & industry
Applications
DescriptionH-GLU-ASP-OH is a dipeptide synthesised from two amino acids (glutamic acid and aspartic acid). It is present in the blood of patients with Gaucher disease and can be used as a diagnostic indicator of the disease. It is also an intermediate in the synthesis of glycoproteins and proteoglycans, which are important components of connective tissue. It has been found to be hydrophobic and acidic and therefore can be used in reversed-phase high-performance liquid chromatography (RP-HPLC) analysis. It is also important for the production of interleukins, which may play a role in Gaucher disease.
UsesGlu-Asp-OH is a useful research chemical used in the synthesis of amino acid- or dipeptide-functionalized bis(arylmethylene)piperidinones as proteasome inhibitors for treatment of cervical cancer.
Suppliers52 total
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
江苏吉泰肽业科技有限公司18936337900 18936337900 · [email protected]
深圳市迈思立生物科技有限公司15977887120 15977887120 · [email protected]
Shandong Hanjiang Chemical Co., Ltd+86-0533-2066820 +8618369939125 · [email protected]
浙江华军药业有限公司0571-17315361885 17315361885 · [email protected]
上海鸿肽生物科技有限公司15318089928 · [email protected]
中科华药(江苏)生物科技有限公司18020125070 · [email protected]
梯希爱（上海）化工贸易有限公司021-61109150 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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