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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1003Generated: October 25, 2026

1,4-Dioxaspiro[4.5]decan-8-ol, 8-(4-methylbenzenesulfonate) → 4-[O-Benzyl-N-(1,4-dioxaspiro[4.5]dec-8-yl)hydroxylamino]-3-methoxy-2-methylpyridine

https://huagongshe.com/reaction/1003

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-Dioxaspiro[4.5]decan-8-ol, 8-(4-methylbenzenesulfonate)HCID 567489—
Reactant4-(O-Benzylhydroxylamino)-3-methoxy-2-methylpyridineHCID 15279358—
Product4-[O-Benzyl-N-(1,4-dioxaspiro[4.5]dec-8-yl)hydroxylamino]-3-methoxy-2-methylpyridineHCID 1969402870%

Reaction Steps

Prepared analogously to Example 5 from 4-(O-benzylhydroxylamino)-3-methoxy-2-methylpyridine and 8-tosyloxy-1,4-dioxaspiro[4.5]decane. Yield: 70%

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05723450
Source datasetuspto-grants-1998_03
ORD IDord-d2942481069b43c48c9121e0d8415d47
Source noteuspto-grants-1998_03