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Palmitoyl chloride → HCID 136341911, compound

HRID 1005368
Notes
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Reaction equation

HRID 1005368 reaction equation
[C:1]([C@@:18]1([N:26]2[C:36]3[N:35]=[C:33]([NH2:34])[NH:32][C:30](=[O:31])[C:29]=3[N:28]=[CH:27]2)[O:25][C@H:22]([CH2:23][OH:24])[C@@H:20]([OH:21])[CH2:19]1)(=[O:17])[CH2:2][CH2:3][CH2:4]CCCCCCCCCCCC.C(Cl)(=O)CCC.C(Cl)(=O)CCCCCCCCCCCCCCC>>[C:1]([C@@:18]1([N:26]2[C:36]3[N:35]=[C:33]([NH2:34])[NH:32][C:30](=[O:31])[C:29]=3[N:28]=[CH:27]2)[O:25][C@H:22]([CH2:23][OH:24])[C@@H:20]([OH:21])[CH2:19]1)(=[O:17])[CH2:2][CH2:3][CH3:4]
ParticipantsProcedureWorkupSources & evidenceReaction notes

Participants

4

Reactant 3

HCID 8206Palmitoyl chlorideHCID 8855Butyryl chlorideHCID 136333583HCID 136333583, compound

Product 1

HCID 136341911HCID 136341911, compound

Procedure

This compound was prepared using the procedure for palmitoyl-2'-deoxyguanosine, substituting the appropriate amount of butyryl chloride for palmitoyl chloride, and isolating as follows: evaporating the solvent after 72 hours, triturating the resulting material in 1:1 diethyl ether-ethyl acetate, and recovering the product by filtration.

Workup

  1. customThis compound was prepared
  • customisolating
  • customevaporating the solvent after 72 hours
  • customtriturating the resulting material in 1:1 diethyl ether-ethyl acetate
  • customrecovering the product
  • filtrationby filtration
  • Sources & evidence

    ORD record
    ord-b9862e1aa70848fc931ed667f8702093
    Source dataset
    uspto-grants-2000_04
    DOI
    10.6084/m9.figshare.5104873.v1
    Patent number
    US06054441

    Reaction notes

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    On this pageParticipantsProcedureWorkupSources & evidenceReaction notes