HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 4-[4-(O-Benzyloximino)cyclohexylamino]-3-methoxy-2-methylpyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | O-Benzylhydroxylamine | HCID 102313 | — |
| Reactant | 4-(4-Oxocyclohexylamino)-3-methoxy-2-methylpyridine | HCID 19693951 | — |
| Reactant | Ethylacetate methanol | HCID 21584119 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 4-[4-(O-Benzyloximino)cyclohexylamino]-3-methoxy-2-methylpyridine | HCID 19693973 | — |
Reaction Steps
2 g of 4-(4-oxocyclohexylamino)-3-methoxy-2-methylpyridine and 1.2 g O-benzylhydroxylamine are boiled in toluene in a water separator until liberation of water has ended. The product is isolated by column chromatography (ethyl acetate/methanol 9:1; silica gel). 1.8 g=53%
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05723450 |
| Source dataset | uspto-grants-1998_03 |
| ORD ID | ord-7b74a27dcc2940b5b3a704ddbd2de98d |
| Source note | uspto-grants-1998_03 |