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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1007184Generated: October 25, 2026

4-Ethoxy-2-nitroaniline → 6-Chloro-N-(4-ethoxy-2-nitrophenyl)-3-pyridinecarboxamide

https://huagongshe.com/reaction/1007184

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Ethoxy-2-nitroanilineHCID 69229—
Reactant6-Chloronicotinoyl ChlorideHCID 2782165—
Product6-Chloro-N-(4-ethoxy-2-nitrophenyl)-3-pyridinecarboxamideHCID 9840127—

Reaction Steps

The title compound was prepared from 6-chloronicotinoyl chloride and 4-ethoxy-2-nitroaniline and was obtained as a yellow solid as described in Example 1. 1H NMR (CDCl3): 11.13 (s, 1H), 9.01 (d, J=2.4, 1H), 8.82 (d, J=9.3, 1H), 8.24-8.20 (m, 1H), 7.74 (d, J=3.0, 1H), 7.51 (d, J=7.8, 1H), 7.34-7.30(m, 1H), 4.11 (q, J=6.9, 2H), 1.47 (t, J=6.9, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06794397B2
Source datasetuspto-grants-2004_09
ORD IDord-49b35d11275d4122a82d2d99e7daf1dd
Source noteuspto-grants-2004_09